(Q36024071)

11 August 2017

A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin (English)

1 reference

11 August 2017

Chunmei Yang

1

1 reference

11 August 2017

Jinong Feng

2

1 reference

11 August 2017

Wenjia Song

3

1 reference

11 August 2017

Jicheng Wang

4

1 reference

11 August 2017

Becky Tsai

5

1 reference

11 August 2017

Yunwu Zhang

6

1 reference

11 August 2017

William A Scaringe

7

1 reference

11 August 2017

Kathleen A Hill

8

1 reference

11 August 2017

Paris Margaritis

9

1 reference

11 August 2017

Katherine A High

10

1 reference

11 August 2017

Steve S Sommer

11

1 reference

11 August 2017

language of work or name

English

0 references

publication date

19 September 2007

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

104

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11 August 2017

39

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11 August 2017

15394-15399

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PTC124 targets genetic disorders caused by nonsense mutations

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Enhanced production of functional proteins from defective genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Gentamicin-Induced Correction of CFTR Function in Patients with Cystic Fibrosis andCFTRStop Mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Comparison of cytotoxicity of aminoglycoside antibiotics using a panel cellular biotest system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Three, four or more: the translational stop signal at length

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Complementary Oligonucleotide Binding to the Anticodon Loop of fMet-transfer RNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Mistranslation in a eucaryotic organism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Nonsense mutations: running the red light

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Skin and mucous membrane ulceration in beagle dogs following oral dosing with an experimental aminoglycoside antibiotic

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Molecular cloning of a cDNA encoding canine factor IX.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000501

Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Aminoglycoside pretreatment partially restores the function of truncated V(2) vasopressin receptors found in patients with nephrogenic diabetes insipidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Aminoglycoside suppression of nonsense mutations in severe hemophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Posttranslational modifications of recombinant myotube-synthesized human factor IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Megalin Deficiency Offers Protection from Renal Aminoglycoside Accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0610878104

Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy

21 January 2018

1 reference

12 December 2020

Misreading of RNA codewords induced by aminoglycoside antibiotics

1 reference

12 December 2020

Aminoglycoside antibiotics and eukaryotic protein synthesis: stimulation of errors in the translation of natural messengers in extracts of cultured human cells

1 reference

12 December 2020

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

1 reference

12 December 2020

The influence of 5' codon context on translation termination in Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0610878104

1 reference

11 August 2017

0 references

1 reference

11 August 2017

1 reference