(Q34003720)

30 July 2017

PTC124 targets genetic disorders caused by nonsense mutations (English)

1 reference

30 July 2017

Ellen M Welch

1

1 reference

30 July 2017

Elisabeth R Barton

2

1 reference

30 July 2017

Jin Zhuo

3

1 reference

30 July 2017

Yuki Tomizawa

4

1 reference

30 July 2017

Westley J Friesen

5

1 reference

30 July 2017

Panayiota Trifillis

6

1 reference

30 July 2017

Sergey Paushkin

7

1 reference

30 July 2017

Meenal Patel

8

1 reference

30 July 2017

Christopher R Trotta

9

1 reference

30 July 2017

Seongwoo Hwang

10

1 reference

30 July 2017

Richard G Wilde

11

1 reference

30 July 2017

Gary Karp

12

1 reference

30 July 2017

James Takasugi

13

1 reference

30 July 2017

Guangming Chen

14

1 reference

30 July 2017

Stephen Jones

15

1 reference

30 July 2017

Hongyu Ren

16

1 reference

30 July 2017

Young-Choon Moon

17

1 reference

30 July 2017

Donald Corson

18

1 reference

30 July 2017

Anthony A Turpoff

19

1 reference

30 July 2017

Jeffrey A Campbell

20

1 reference

30 July 2017

M Morgan Conn

21

1 reference

30 July 2017

Atiyya Khan

22

1 reference

30 July 2017

Neil G Almstead

23

1 reference

30 July 2017

Jean Hedrick

24

1 reference

30 July 2017

Anna Mollin

25

1 reference

30 July 2017

Nicole Risher

26

1 reference

30 July 2017

Marla Weetall

27

1 reference

30 July 2017

Shirley Yeh

28

1 reference

30 July 2017

Arthur A Branstrom

29

1 reference

30 July 2017

Joseph M Colacino

30

1 reference

30 July 2017

John Babiak

31

1 reference

30 July 2017

William D Ju

32

1 reference

30 July 2017

Samit Hirawat

33

1 reference

30 July 2017

Valerie J Northcutt

34

1 reference

30 July 2017

Langdon L Miller

35

1 reference

30 July 2017

Phyllis Spatrick

36

1 reference

30 July 2017

Feng He

37

1 reference

30 July 2017

Masataka Kawana

38

1 reference

30 July 2017

Huisheng Feng

39

1 reference

30 July 2017

Allan Jacobson

40

1 reference

30 July 2017

Stuart W Peltz

41

1 reference

30 July 2017

H Lee Sweeney

42

1 reference

30 July 2017

language of work or name

English

0 references

publication date

22 April 2007

1 reference

30 July 2017

1 reference

30 July 2017

447

1 reference

30 July 2017

87-91

1 reference

30 July 2017

7140

1 reference

https://scigraph.springernature.com/pub.10.1038/nature05756

30 July 2017

0 references

cites work

When the message goes awry: disease-producing mutations that influence mRNA content and performance.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Pharmacologic therapy for stop mutations: how much CFTR activity is enough?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Five Percent of Normal Cystic Fibrosis Transmembrane Conductance Regulator mRNA Ameliorates the Severity of Pulmonary Disease in Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Early nonsense: mRNA decay solves a translational problem

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Gentamicin-Induced Correction of CFTR Function in Patients with Cystic Fibrosis andCFTRStop Mutations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Translational termination efficiency in mammals is influenced by the base following the stop codon.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Dystrophin protects the sarcolemma from stresses developed during muscle contraction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Safety, tolerability, and pharmacokinetics of PTC124, a nonaminoglycoside nonsense mutation suppressor, following single- and multiple-dose administration to healthy male and female adult volunteers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

RefSeq and LocusLink: NCBI gene-centered resources

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

An mRNA surveillance mechanism that eliminates transcripts lacking termination codons

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05756

7 January 2021

Identifiers

DOI

10.1038/NATURE05756

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference