(Q36025616)

11 August 2017

1 reference

title

Resistance to cytostatic drugs at the cellular level (English)

1 reference

11 August 2017

C. P. Vendrik

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1568284

9 October 2022

J. J. Bergers

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1568284

9 October 2022

W. H. De Jong

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1568284

9 October 2022

P. A. Steerenberg

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1568284

9 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1568284

9 October 2022

publication date

1 January 1992

1 reference

Cancer Chemotherapy and Pharmacology

11 August 2017

published in

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11 August 2017

volume

29

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11 August 2017

issue

6

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11 August 2017

page(s)

413-429

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Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines

11 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Protection against the toxicity of alkylating agents by thiols: The mechanism of protection and its relevance to cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Increased dihydrofolate reductase activity in methotrexate-resistant human promyelocytic-leukaemia (HL-60) cells. Lack of correlation between increased activity and overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Simultaneous expression of two P-glycoprotein genes in drug-sensitive Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Drug resistance and membrane alteration in mutants of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Increased sensitivity of chronic lymphocytic leukemia lymphocytes to alkylating agents due to a deficient DNA repair mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Changes of molecular properties associated with the development of resistance against methotrexate in human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Co-Amplification of Double Minute Chromosomes, Multiple Drug Resistance, and Cell Surface P-Glycoprotein in DNA-Mediated Transformants of Mouse Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Thymidylate Synthetase Overproduction in 5-Fluorodeoxyuridine-Resistant Mouse Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Chromosomal and extrachromosomal localization of amplified dihydrofolate reductase genes in cultured mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

The metabolism of cytosine arabinoside as a predictive test for clinical response to the drug in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00684841

Extent of the requirement for folate transport by L1210 cells for growth and leukemogenesis in vivo.

21 January 2018

1 reference

12 December 2020

Restored in vitro sensitivity of adriamycin- and vincristine-resistant P388 leukemia with reserpine

1 reference

12 December 2020

Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance.

1 reference

12 December 2020

Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers.

1 reference

12 December 2020

Dominance of colchicine resistance in hybrid CHO cells

1 reference

12 December 2020

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

1 reference

12 December 2020

Active efflux of daunorubicin and adriamycin in sensitive and resistant sublines of P388 leukemia

1 reference

12 December 2020

Development of methotrexate resistance in a human squamous cell carcinoma of the head and neck in culture

1 reference

12 December 2020

Membrane alterations associated with progressive adriamycin resistance.

1 reference

12 December 2020

Mechanism of cross-resistance between vincristine and daunorubicin in Ehrlich ascites tumor cells

1 reference

12 December 2020

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients

1 reference

12 December 2020

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis

1 reference

12 December 2020

Biochemical characterization of fluoropyrimidine-resistant murine leukemic cell lines.

1 reference

12 December 2020

Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts

1 reference

12 December 2020

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

1 reference

12 December 2020

Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma

1 reference

12 December 2020

Alkaline phosphatase activities of 6-thiopurine-sensitive and -resistant sublines of Sarcoma 180

1 reference

12 December 2020

Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues

1 reference

12 December 2020

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

1 reference

12 December 2020

A phosphoglycoprotein associated with taxol resistance in J774.2 cells.

1 reference

12 December 2020

Multidrug-resistance phenotype in Chinese hamster ovary cells

1 reference

12 December 2020

Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers.

1 reference

12 December 2020

Dechlorination of L-phenylalanine mustard by sensitive and resistant tumor cells and its relationship to intracellular glutathione content.

1 reference

12 December 2020

Differential oxygen radical susceptibility of adriamycin-sensitive and -resistant MCF-7 human breast tumor cells

1 reference

12 December 2020

Metallothionein gene expression and resistance to cisplatin in human ovarian cancer

1 reference

12 December 2020

Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line

1 reference

12 December 2020

Mutants of Chinese hamster ovary (CHO) cells with altered colcemid-binding affinity.

1 reference

12 December 2020

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1 reference

12 December 2020

Cross-resistance to intercalating agents in an epipodophyllotoxin-resistant Chinese hamster ovary cell line: evidence for a common intracellular target

1 reference

12 December 2020

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1 reference

12 December 2020

P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high-dose verapamil

1 reference

12 December 2020

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1 reference

12 December 2020

Effects of sulfhydryl inhibitors upon transport of folate compounds into L1210 cells

1 reference

12 December 2020

Cytidine deaminase and the development of resistance to arabinosyl cytosine.

1 reference

12 December 2020

Lack of drug-induced DNA cross-links in chlorambucil-resistant Chinese hamster ovary cells.

1 reference

12 December 2020

Unstable Methotrexate Resistance in Human Small-Cell Carcinoma Associated with Double Minute Chromosomes

1 reference

12 December 2020

Protective role of the glutathione redox cycle against adriamycin-mediated toxicity in isolated hepatocytes

1 reference

12 December 2020

The role of membranes in the mechanism of action of the antineoplastic agent adriamycin. Spin-labeling studies with chronically hypoxic and drug-resistant tumor cells.

1 reference

12 December 2020

Mechanisms of resistance to cisplatin and alkylating agents.

1 reference

12 December 2020

Quenching of DNA:platinum(II) monoadducts as a possible mechanism of resistance to cis-diamminedichloroplatinum(II) in L1210 cells.

1 reference

12 December 2020

Promotion by verapamil of vincristine responsiveness in tumor cell lines inherently resistant to the drug

1 reference

12 December 2020

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

1 reference

12 December 2020

Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells

1 reference

12 December 2020

Dihydrofolate reductase gene amplification and possible rearrangement in estrogen-responsive methotrexate-resistant human breast cancer cells.

1 reference

12 December 2020

Folate requirements of methotrexate-resistant human acute lymphoblastic leukemia cell lines.

1 reference

12 December 2020

Transport of Nitrogen Mustard on the Transport-Carrier for Choline in L5178Y Lymphoblasts

1 reference

12 December 2020

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling

1 reference

12 December 2020

Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells

1 reference

12 December 2020

Expression of a multidrug resistance gene in human cancers

1 reference

12 December 2020

Enhancement of doxorubicin and vinblastine sensitivity in anthracycline-resistant P388 cells

1 reference

12 December 2020

Drug-binding macromolecular lipids from L1210 leukemia tumors

1 reference

12 December 2020

Expression of the multidrug transporter, P-glycoprotein, in acute leukemia cells and correlation to clinical drug resistance.

1 reference

12 December 2020

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

1 reference

12 December 2020

Multidrug resistance in ovarian cancer

1 reference

12 December 2020

Mechanism of the Cytotoxic Action of Alkylating Agents in Mammalian Cells and Evidence for the Removal of Alkylated Groups from Deoxyribonucleic Acid

1 reference

12 December 2020

Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells

1 reference

12 December 2020

Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16

1 reference

12 December 2020

Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability

1 reference

12 December 2020

Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines.

1 reference

12 December 2020

Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo

1 reference

12 December 2020

Resistance of in vitro grown IgM immunocytoma cells to cis-diamminedichloroplatinum (II) (cis-DDP) and cross-resistance to other DNA interacting drugs

1 reference

12 December 2020

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes

1 reference

12 December 2020

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

1 reference

12 December 2020

Gene amplification and drug resistance in cultured murine cells.

1 reference

12 December 2020

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate

1 reference

12 December 2020

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

1 reference

12 December 2020

Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents

1 reference

12 December 2020

Methotrexate-resistant human promyelocytic leukemia (HL-60) cells express a dihydrofolate reductase with altered properties associated with increased enzyme activity.

1 reference

12 December 2020

Increased resistance to chlorambucil in cultured cells with a high concentration of cytoplasmic metallothionein.

1 reference

12 December 2020

The human mdr3 gene encodes a novel P-glycoprotein homologue and gives rise to alternatively spliced mRNAs in liver

1 reference

12 December 2020

Resistance to 5-fluorouracil associated with increased cytidine triphosphate levels in V79 Chinese hamster cells

1 reference

12 December 2020

Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance

1 reference

12 December 2020

Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts

1 reference

12 December 2020

Phorbol esters induce multidrug resistance in human breast cancer cells

1 reference

12 December 2020

Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells

1 reference

12 December 2020

Resistance against cis-dichlorodiammineplatinum in cultured cells with a high content of metallothionein.

1 reference

12 December 2020

Studies on 1-beta-D-arabinofuranosyl-cytosine-resistant mutants of Chinese-hamster fibroblasts. A mitochondrial deoxycytidine kinase devoid of activity on arabino-cytosine.

1 reference

12 December 2020

Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine

1 reference

12 December 2020

Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours

1 reference

12 December 2020

Characterization of a human squamous carcinoma cell line resistant to cis-diamminedichloroplatinum(II).

1 reference

12 December 2020

Antifolate-resistant Chinese Hamster Cells. mRNA directed overproduction of multiple dihydrofolate reductases from a series of independently derived sublines containing amplified dihydrofolate reductase genes.

1 reference

12 December 2020

Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action.

1 reference

12 December 2020

Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines

1 reference

12 December 2020

Cell surface-mediated cytotoxicity of polymer-bound Adriamycin against drug-resistant hepatocytes.

1 reference

12 December 2020

Reduction in glutathione content of L-PAM resistant L1210 Cells confers drug sensitivity.

1 reference

12 December 2020

Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.

1 reference

12 December 2020

Methyltetrahydrofolic acid mediates N- and O-methylation of biogenic amines

1 reference

12 December 2020

Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide

1 reference

12 December 2020

Reduced formation of protein-associated DNA strand breaks in Chinese hamster cells resistant to topoisomerase II inhibitors

1 reference

12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

12 December 2020

Mechanisms regulating cell resistance to adriamycin. Evidence that drug accumulation in resistant cells is modulated by phosphorylation of a plasma membrane glycoprotein

1 reference

12 December 2020

Effects of calcium antagonists in multidrug resistant primary human renal cell carcinomas

1 reference

12 December 2020

Leukocyte purine phosphoribosyltransferases in human leukemias sensitive and resistant to 6-thiopurines

1 reference

12 December 2020

Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells

1 reference

12 December 2020

Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis

1 reference

12 December 2020

In situ selection of a human rhabdomyosarcoma resistant to vincristine with altered beta-tubulins.

1 reference

12 December 2020

Mechanisms of resistance of human acute leukaemia cells to cytosine arabinoside.

1 reference

12 December 2020

Repair of DNA interstrand crosslinks after busulphan. A possible mode of resistance.

1 reference

12 December 2020

Glutathione depletion reverses cisplatin resistance in murine L1210 leukemia cells

1 reference

12 December 2020

Increased expression of glutathione S-transferase gene in cis-diamminedichloroplatinum(II)-resistant variants of a Chinese hamster ovary cell line.

1 reference

12 December 2020

Characterization of acquired epipodophyllotoxin resistance in a Chinese hamster ovary cell line: loss of drug-stimulated DNA cleavage activity

1 reference

12 December 2020

Anthracycline resistance in P388 murine leukemia and its circumvention by calcium antagonists

1 reference

12 December 2020

Verapamil Restoration of Daunorubicin Responsiveness in Daunorubicin-resistant Ehrlich Ascites Carcinoma

1 reference

12 December 2020

Immunological studies on alkaline phosphatases of 6-thiopurine-sensitive and -resistant sublines of Sarcoma 180.

1 reference

12 December 2020

Verapamil enhancement of antitumor effect of cis-diamminedichloroplatinum(II) in nude mouse-grown human neuroblastoma

1 reference

12 December 2020

Reversal of multidrug resistance by verapamil and modulation by alpha 1-acid glycoprotein in wild-type and multidrug-resistant Chinese hamster ovary cell lines

1 reference

12 December 2020

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1 reference

12 December 2020

Detection of a multidrug resistant phenotype in acute non-lymphoblastic leukaemia.

1 reference

12 December 2020

Enhanced efflux of actinomycin D, vincristine, and vinblastine in adriamycin-resistant subline of P388 leukemia

1 reference

12 December 2020

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

12 December 2020

Bleomycin hydrolase: molecular cloning, sequencing, and biochemical studies reveal membership in the cysteine proteinase family

1 reference

12 December 2020

Transport and metabolism of methotrexate in normal and resistant cultured rat hepatoma cells

1 reference

12 December 2020

Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells.

1 reference

12 December 2020

Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions

1 reference

12 December 2020

Combined modalities of resistance in etoposide-resistant human KB cell lines.

1 reference

12 December 2020

Isolation and expression of a complementary DNA that confers multidrug resistance

1 reference

12 December 2020

Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus

1 reference

12 December 2020

Metaphase chromosome anomaly: association with drug resistance and cell-specific products

1 reference

12 December 2020

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide

1 reference

12 December 2020

A Kinetic Analysis of the Uptake of Cytosine-beta-d-Arabinoside by Rat-B77 Cells. Differentiation between Transport and Phosphorylation

1 reference

12 December 2020

Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts

1 reference

12 December 2020

Resistance to methotrexate due to gene amplification in a patient with acute leukemia

1 reference

12 December 2020

Reduction in cellular glutathione by buthionine sulfoximine and sensitization of murine tumor cells resistant to L-phenylalanine mustard.

1 reference

12 December 2020

Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines.

1 reference

12 December 2020

Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants

1 reference

12 December 2020

Mechanism of multidrug resistance

1 reference

12 December 2020

Effects of tunicamycin on anthracycline resistance in P388 murine leukemia cells

1 reference

12 December 2020

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

12 December 2020

Characterization of dihydrofolate reductase-related DNA and RNA from human KB cell subclones containing different amounts of enzyme

1 reference

12 December 2020

Platinum concentrations and DNA adduct levels in tumors and organs of cisplatin-treated LOU/M rats inoculated with cisplatin-sensitive or -resistant immunoglobulin M immunocytoma.

1 reference

12 December 2020

Heterogeneous DNA damage and repair in the mammalian genome

1 reference

12 December 2020

Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards

1 reference

12 December 2020

Plasma membrane lipid structural order in doxorubicin-sensitive and -resistant P388 cells

1 reference

12 December 2020

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells

1 reference

12 December 2020

Isolation and characterization of the multiple forms of dihydrofolate reductase from methotrexate-resistant hamster cells.

1 reference

12 December 2020

Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.

1 reference

12 December 2020

Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines

1 reference

12 December 2020

Metabolic inactivation: a mechanism of human tumor resistance to bleomycin.

1 reference

12 December 2020

Identification of a multidrug resistance associated antigen (P-glycoprotein) in normal human tissues

1 reference

12 December 2020

Defective removal of DNA cross-links in a repair-deficient mutant of Chinese hamster cells.

1 reference

12 December 2020

STUDIES ON TUMOR RESISTANCE TO 5-FLUOROURACIL

1 reference

12 December 2020

Resistance and cross-resistance of the IgM immunocytoma in the LOU/M Wsl rat for cisplatin, carboplatin, and iproplatin.

1 reference

12 December 2020

Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion.

1 reference

12 December 2020

Mixed-function oxidase enzymes in adriamycin-sensitive and resistant sublines of P-388 leukemia.

1 reference

12 December 2020

Thymidine kinase as a determinant of the response to 5-fluoro-2'-deoxyuridine in transplantable murine leukemias

1 reference

12 December 2020

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

1 reference

12 December 2020

The anticancer agent adriamycin can be actively cytotoxic without entering cells

1 reference

12 December 2020

MECHANISMS OF RESISTANCE TO ANTICANCER AGENTS.

1 reference

12 December 2020

Transport of melphalan by sensitive and resistant L1210 cells

1 reference

12 December 2020

Characterization of the methotrexate transport defect in a resistant L 1210 lymphoma cell line.

1 reference

12 December 2020

Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate

1 reference

12 December 2020

Establishment of a human leukemia subline resistant to the growth-inhibitory effect of 12-o-tetradecanoylphorbol 13-acetate (TPA) and showing non-P-glycoprotein-mediated multi-drug resistance

1 reference

12 December 2020

Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein

1 reference

12 December 2020

Gene amplification in a leukemic patient treated with methotrexate

1 reference

12 December 2020

Cross-resistance and glutathione-S-transferase-pi levels among four human melanoma cell lines selected for alkylating agent resistance

1 reference

12 December 2020

Continued expression of vinca alkaloid resistance by CCRF-CEM cells after treatment with tunicamycin or pronase.

1 reference

12 December 2020

Formation and repair of cisplatin-induced adducts to DNA in cultured normal and repair-deficient human fibroblasts.

1 reference

12 December 2020

Enhancement of antineoplastic effects of cisplatin by calmodulin antagonists in nude mice bearing human ovarian carcinoma

1 reference

12 December 2020

Transfectant CHO cells expressing O6-alkylguanine-DNA-alkyltransferase display increased resistance to DNA damage other than O6-guanine alkylation

1 reference

12 December 2020

Functions of metallothionein

1 reference

12 December 2020

Overproduction of two antigenically distinct forms of dihydrofolate reductase in a highly methotrexate-resistant mouse leukemia cell line

1 reference

12 December 2020

Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

1 reference

12 December 2020

Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin

1 reference

12 December 2020

Characteristics of transport of 4-amino antifolates and folate compounds by two lines of L5178Y lymphoblasts, one with impaired transport of methotrexate

1 reference

12 December 2020

Increased activity of alkaline phosphatase in leukemic cells from patients resistant to thiopurines

1 reference

12 December 2020

Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer

1 reference

12 December 2020

Podophyllotoxin-resistant mutants of Chinese hamster ovary cells. Alteration in a microtubule-associated protein.

1 reference

12 December 2020

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

12 December 2020

The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus

1 reference

12 December 2020

Active efflux common to vincristine and daunorubicin in vincristine-resistant P388 leukemia

1 reference

12 December 2020

Alkylating agents: in vitro studies of cross-resistance patterns in human cell lines.

1 reference

12 December 2020

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

1 reference

12 December 2020

Expression of a multidrug-resistance gene in human tumors and tissues

1 reference

12 December 2020

Bleomycin-resistant cells contain increased bleomycin-hydrolase activities

1 reference

12 December 2020

Mechanisms of resistance to 6-thiopurines in human leukemia

1 reference

12 December 2020

Patterns of Resistance and Therapeutic Synergism among Alkylating Agents1

1 reference

12 December 2020

Evolution of methotrexate resistance of human acute lymphoblastic leukemia cells in vitro.

1 reference

12 December 2020

Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione

1 reference

12 December 2020

A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine

1 reference

12 December 2020

Synthesis of adriamycin-coupled polyglutaraldehyde microspheres and evaluation of their cytostatic activity

1 reference

12 December 2020

Mechanisms of resistance to daunorubicin in Ehrlich ascites tumor cells

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

12 December 2020

Acquired methotrexate resistance in lymphoblasts resulting from altered kinetic properties of dihydrofoltate reductase

1 reference

12 December 2020

Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein

1 reference

12 December 2020

Evidence for a transport carrier of nitrogen mustard in nitrogen mustard-sensitive and -resistant L5178Y lymphoblasts

1 reference

12 December 2020

Experimental chemotherapy of neuroblastoma. II. Increased thymidylate synthetase activity in a 5-fluorodeoxyuridine-resistant variant of mouse neuroblastoma

1 reference

12 December 2020

Characterization of cisplatin-resistant COLO 316 human ovarian carcinoma cells

1 reference

12 December 2020

Repair of alkylated DNA in mammalian cells

1 reference

12 December 2020

Basis for natural variation in sensitivity to 5-fluorouracil in mouse and human cells in culture.

1 reference

12 December 2020

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines

1 reference

12 December 2020

Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line

1 reference

12 December 2020

P-glycoprotein in human sarcoma: evidence for multidrug resistance

1 reference

12 December 2020

PURINE NUCLEOTIDE PYROPHOSPHORYLASES IN 6-MERCAPTOPURINE-SENSITIVE AND -RESISTANT HUMAN LEUKEMIAS

1 reference

12 December 2020

Isolation and characterization of Chinese hamster ovary cell lines sensitive to mitomycin C and bleomycin.

1 reference

12 December 2020

Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine

1 reference

12 December 2020

Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

1 reference

12 December 2020

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1 reference

12 December 2020

Elevated pentose cycle and glucuronyltransferase in daunorubicin-resistant P388 cells.

1 reference

12 December 2020

Studies on 1-?-D-arabinofuranosyl cytosine-resistant mutants of Chinese hamster fibroblasts: III. Joint resistance to arabinofuranosyl cytosine and to excess thymidine?A semidominant manifestation of deoxycytidine triphosphate pool expansion

1 reference

12 December 2020

Tumours from a cell strain with a high content of metallothionein show enhanced resistance against cis-dichlorodiammineplatinum.

1 reference

12 December 2020

CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin

1 reference

12 December 2020

Studies on the resistance of a murine leukemia L1210 cell line cis-diamminedichloroplatinum (II).

1 reference

12 December 2020

Mode of action of calcium antagonists which alter anthracycline resistance.

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12 December 2020

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein

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12 December 2020

Cross resistance between actinomycin-D, adriamycin and vincristine in a murine solid tumour in vivo.

1 reference

12 December 2020

Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links.

1 reference

12 December 2020

Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases

1 reference

12 December 2020

Single cell analysis of daunomycin uptake and efflux in multidrug-resistant and -sensitive KB cells: effects of verapamil and other drugs.

1 reference

12 December 2020

Alterations in cell surface membranes in Chinese hamster lung cell resistant to adriamycin.

1 reference

12 December 2020

Potentiation of etoposide-induced DNA damage by calcium antagonists in L1210 cells in vitro

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12 December 2020

Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance

1 reference

12 December 2020

Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance.

1 reference

12 December 2020

In vitro selection and characterization of a bleomycin-resistant subline of B16 melanoma.

1 reference

12 December 2020

Decreased accumulation as a mechanism of resistance to cis-diamminedichloroplatinum(II) in human non-small cell lung cancer cell lines: relation to DNA damage and repair

1 reference

12 December 2020

Cross-linking of glutathione to DNA by cancer chemotherapeutic platinum coordination complexes

1 reference

12 December 2020

Studies on drug resistance—II. Kinase patterns in P815 neoplasms sensitive and resistant to 1-β-d-arabinofuranosylcytosine

1 reference

12 December 2020

Isolation and Characterization of a Mutant Mouse Lymphoma Cell Sensitive to Methyl Methanesulfonate and X Rays

1 reference

12 December 2020

Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues.

1 reference

12 December 2020

Reversal of Vinca alkaloid resistance but not multiple drug resistance in human leukemic cells by verapamil

1 reference

12 December 2020

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.

1 reference

12 December 2020

Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells.

1 reference

12 December 2020

Studies on resistance against 5-fluorouracil. I. Enzymes of the uracil pathway during development of resistance

1 reference

12 December 2020

Drug resistance in cancer

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12 December 2020

Establishment of dihydrofolate reductase-increased human cell lines and relationship between dihydrofolate reductase levels and gene copy.

1 reference

12 December 2020

Development of resistance to 1-beta-D-arabinofuranosylcytosine after high-dose treatment in childhood lymphoblastic leukemia: analysis of resistance mechanism in established cell lines

1 reference

12 December 2020

Modification of in vivo methotrexate antitumor effect in L1210 leukemia by induced impairment of purine salvage

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00684841

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11 August 2017

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