(Q36033174)

11 August 2017

Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement (English)

1 reference

11 August 2017

3

Scott X Atwood

1 reference

11 August 2017

Chiharu Graybill

1

1 reference

11 August 2017

Brett Wee

series ordinal

2

1 reference

11 August 2017

Kenneth E Prehoda

series ordinal

4

1 reference

11 August 2017

language of work or name

English

0 references

publication date

27 April 2012

1 reference

11 August 2017

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

11 August 2017

287

1 reference

11 August 2017

21003-21011

1 reference

11 August 2017

25

1 reference

describes a project that uses

11 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3375524/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3375524/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Regulation of protein kinases by lipids

1 reference

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Allosteric regulation of protein kinase PKCζ by the N-terminal C1 domain and small compounds to the PIF-pocket

2 October 2017

1 reference

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Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Elaborating polarity: PAR proteins and the cytoskeleton

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Crystal Structure and Allosteric Activation of Protein Kinase C βII

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Asymmetric cell division: recent developments and their implications for tumour biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

PKC and the control of localized signal dynamics.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Polarization of Drosophila neuroblasts during asymmetric division

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Protein kinase C: poised to signal

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

The PAR proteins: fundamental players in animal cell polarization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Interdomain interactions in the tumor suppressor discs large regulate binding to the synaptic protein GukHolder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Cell signaling and function organized by PB1 domain interactions.

2 October 2017

1 reference

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C1 domains exposed: from diacylglycerol binding to protein-protein interactions

2 October 2017

1 reference

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The PAR-aPKC system: lessons in polarity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Increased membrane affinity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Structure of a cell polarity regulator, a complex between atypical PKC and Par6 PB1 domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Determination of the specific substrate sequence motifs of protein kinase C isozymes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Dual role of pseudosubstrate in the coordinated regulation of protein kinase C by phosphorylation and diacylglycerol

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Protein kinase C zeta isoform is critical for mitogenic signal transduction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3375524

The influence of basic residues on the substrate specificity of protein kinase C

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22544755

12 December 2020

inferred from PubMed ID database lookup

Assay of protein kinases using radiolabeled ATP: a protocol

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22544755

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M112.360495

1 reference

release_veuy3h5xdrdgbacpquh5uax7hy

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/veuy3h5xdrdgbacpquh5uax7hy

24 November 2022

mapped directly with Wikidata item

1 reference

11 August 2017

1 reference