(Q36035950)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Beverly M Francis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Jimao Yang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Enid Hajderi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Mary E Brown

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Bernadeta Michalski

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Joanne McLaurin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Howard T J Mount

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

11 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

published in

Neuropsychopharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

1934-1944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

28 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3376325/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/npp.2012.40

0 references

cites work

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Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model

2 October 2017

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Beta-endorphin mediates behavioral despair and the effect of ethanol on the tail suspension test in mice

2 October 2017

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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

2 October 2017

1 reference

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Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity

2 October 2017

1 reference

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Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

2 October 2017

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Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function

2 October 2017

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Behavioral models of Parkinson's disease in rodents: a new look at an old problem

2 October 2017

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Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.

2 October 2017

1 reference

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The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice

2 October 2017

1 reference

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Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

2 October 2017

1 reference

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Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model.

2 October 2017

1 reference

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The role of norepinephrine in the behavioral and psychological symptoms of dementia

2 October 2017

1 reference

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Effects of rivastigmine on behavioral and psychological symptoms of dementia in Alzheimer's disease

2 October 2017

1 reference

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Alzheimer's disease: intraneuronal alterations precede insoluble amyloid-beta formation

2 October 2017

1 reference

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Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

2 October 2017

1 reference

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

2 October 2017

1 reference

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Alzheimer's disease: more than a 'cholinergic disorder' - evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementia

2 October 2017

1 reference

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The cholinergic hypothesis of Alzheimer's disease: a review of progress

2 October 2017

1 reference

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The noradrenergic system in Alzheimer and multi-infarct dementias

2 October 2017

1 reference

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Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

2 October 2017

1 reference

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Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

2 October 2017

1 reference

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Dopamine release in vivo from nigrostriatal, mesolimbic, and mesocortical neurons: utility of 3-methoxytyramine measurements

2 October 2017

1 reference

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Neuropathological stageing of Alzheimer-related changes

2 October 2017

1 reference

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Disease-specific patterns of locus coeruleus cell loss

2 October 2017

1 reference

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Levels of biogenic amines and their metabolites in rat whole brain after rapid tissue fixation with microwave irradiation (author's transl)

2 October 2017

1 reference

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Object recognition memory and BDNF expression are reduced in young TgCRND8 mice.

2 October 2017

1 reference

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Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice.

11 July 2018

1 reference

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Protective effects of the alpha 2-adrenoceptor antagonist, dexefaroxan, against degeneration of the basalocortical cholinergic system induced by cortical devascularization in the adult rat.

11 July 2018

1 reference

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Sequence of Abeta-protein deposition in the human medial temporal lobe.

11 July 2018

1 reference

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Alpha2-adrenoceptor modulation of cortical acetylcholine release in vivo

11 July 2018

1 reference

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Alzheimer's disease: in vivo detection of differential vulnerability of brain regions.

11 July 2018

1 reference

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The topography of cell loss from locus caeruleus in Alzheimer's disease

11 July 2018

1 reference

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Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.

11 July 2018

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Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease.

11 July 2018

1 reference

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11 July 2018

1 reference

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Degeneration of the cholinergic innervation of the locus ceruleus in Alzheimer's disease.

11 July 2018

1 reference

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Changes in the brain catecholamines in patients with dementia of Alzheimer type.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Selective loss of central cholinergic neurons in Alzheimer's disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Regionally selective activation and differential regulation of ERK, JNK and p38 MAP kinase signalling pathway by protein kinase C in mood modulation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Chronic nicotine restores normal Aβ levels and prevents short-term memory and E-LTP impairment in Aβ rat model of Alzheimer's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Adrenergic and noradrenergic innervation of the midbrain ventral tegmental area and retrorubral field: prominent inputs from medullary homeostatic centers

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Increase of BDNF serum concentration during donepezil treatment of patients with early Alzheimer's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

The phenotypic differentiation of locus ceruleus noradrenergic neurons mediated by brain-derived neurotrophic factor is enhanced by corticotropin releasing factor through the activation of a cAMP-dependent signaling pathway.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Activation of noradrenergic transmission by alpha2-adrenoceptor antagonists counteracts deafferentation-induced neuronal death and cell proliferation in the adult mouse olfactory bulb

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

The neurotransmitter noradrenaline rescues septal cholinergic neurons in culture from degeneration caused by low-level oxidative stress.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

BDNF is necessary for maintenance of noradrenergic innervations in the aged rat brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Effects of β-amyloid protein on serotoninergic, noradrenergic, and cholinergic markers in neurons of the pontomesencephalic tegmentum in the rat

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Phases of A beta-deposition in the human brain and its relevance for the development of AD.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Noradrenergic changes, aggressive behavior, and cognition in patients with dementia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Changes in cortical noradrenergic axon terminals of locus coeruleus neurons in aged F344 rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Noradrenergic DSP-4 lesions aggravate impairment of working memory produced by hippocampal muscarinic blockade in rats.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Tactile extinction: distinguishing between sensorimotor and motor asymmetries in rats with unilateral nigrostriatal damage.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3376325

The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPP.2012.40

Noradrenergic mechanisms in neurodegenerative diseases: a theory

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPP.2012.40

The Role of Norepinephrine in the Behavioral and Psychological Symptoms of Dementia

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNPP.2012.40

Pharmacological analysis of a cholinergic receptor mediated regulation of brain norepinephrine neurons

21 January 2018

1 reference

12 December 2020

Locus coeruleus cell loss in the aging human brain: a non-random process

1 reference

12 December 2020

The tail suspension test: a new method for screening antidepressants in mice

1 reference

12 December 2020

In vivo assessment of dopamine and norepinephrine release in rat neocortex: gas chromatography-mass spectrometry measurement of 3-methoxytyramine and normetanephrine

1 reference

12 December 2020

Region-specific distribution of β-amyloid peptide and cytokine expression in TgCRND8 mice

1 reference

12 December 2020

Transmitter deficits in Alzheimer's disease

1 reference

12 December 2020

Identifiers

DOI

10.1038/NPP.2012.40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22491352%20AND%20SRC:MED&resulttype=core&format=json