(Q36040456)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

GATA2 is required for lymphatic vessel valve development and maintenance (English)

1 reference

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20 February 2020

1

1 reference

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20 February 2020

Kelly L Betterman

2

1 reference

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20 February 2020

Chan-Eng Chong

3

1 reference

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20 February 2020

Marjo Salminen

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Jacqueline M Matthews

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Hamish S. Scott

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Natasha Harvey

18

1 reference

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20 February 2020

author name string

Philippa H Stokes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Young K Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Genevieve A Secker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Yan Agalarov

7

1 reference

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20 February 2020

Cansaran Saygili Demir

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

David M Lawrence

9

1 reference

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20 February 2020

Drew L Sutton

10

1 reference

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20 February 2020

Sebastien P Tabruyn

11

1 reference

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20 February 2020

Naoyuki Miura

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Tatiana V Petrova

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Christopher N Hahn

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

27 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

20 February 2020

published in

1 reference

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20 February 2020

volume

125

1 reference

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20 February 2020

issue

8

1 reference

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20 February 2020

page(s)

2979-2994

1 reference

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describes a project that uses

20 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4563742/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Notch signaling functions in lymphatic valve formation

1 reference

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Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation

2 October 2017

1 reference

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Gata2 is required for HSC generation and survival

2 October 2017

1 reference

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Interplay of mechanotransduction, FOXC2, connexins, and calcineurin signaling in lymphatic valve formation

2 October 2017

1 reference

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2 October 2017

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EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance

2 October 2017

1 reference

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Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

2 October 2017

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Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature.

2 October 2017

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Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.

2 October 2017

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DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

2 October 2017

1 reference

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Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

2 October 2017

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Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity

2 October 2017

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Flow control in our vessels: vascular valves make sure there is no way back

2 October 2017

1 reference

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An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation.

2 October 2017

1 reference

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Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

2 October 2017

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Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

2 October 2017

1 reference

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Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves

2 October 2017

1 reference

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Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish

2 October 2017

1 reference

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Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

2 October 2017

1 reference

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Genetic framework for GATA factor function in vascular biology

2 October 2017

1 reference

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Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice

2 October 2017

1 reference

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Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression

2 October 2017

1 reference

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Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

2 October 2017

1 reference

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Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.

2 October 2017

1 reference

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Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space

2 October 2017

1 reference

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Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy

2 October 2017

1 reference

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Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis

2 October 2017

1 reference

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GATA-2 reinforces megakaryocyte development in the absence of GATA-1

2 October 2017

1 reference

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FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

2 October 2017

1 reference

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A mechanosensitive transcriptional mechanism that controls angiogenesis

2 October 2017

1 reference

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Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons

2 October 2017

1 reference

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Sox18 induces development of the lymphatic vasculature in mice

2 October 2017

1 reference

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Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

2 October 2017

1 reference

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Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.

2 October 2017

1 reference

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Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature

2 October 2017

1 reference

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

2 October 2017

1 reference

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Distinct functions of dispersed GATA factor complexes at an endogenous gene locus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

GATA2 is associated with familial early-onset coronary artery disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Development of heart valves requires Gata4 expression in endothelial-derived cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Cross talk between retinoic acid signaling and transcription factor GATA-2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Generalized lacZ expression with the ROSA26 Cre reporter strain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

An early haematopoietic defect in mice lacking the transcription factor GATA-2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Genetic dissection of tie pathway in mouse lymphatic maturation and valve development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Emberger syndrome-Primary lymphedema with myelodysplasia: Report of seven new cases

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563742

Gene polymorphisms associated with susceptibility to coronary artery disease in Han Chinese people

21 October 2018

1 reference

12 December 2020

The early development of the lymphatic system in mouse embryos

1 reference

12 December 2020

A study of the role of GATA2 gene polymorphism in coronary artery disease risk traits

1 reference

12 December 2020

Prox1 function is required for the development of the murine lymphatic system

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI78888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26214525%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

26214525

1 reference