(Q35249294)

7 August 2017

title

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia (English)

1 reference

7 August 2017

1 reference

myelodysplastic syndrome

1 reference

Paul G Ekert

14

0 references

Marshall Horwitz

object named as

Marshall S Horwitz

27

0 references

Hamish S. Scott

object named as

Hamish S Scott

28

0 references

author name string

Christopher N Hahn

1

1 reference

7 August 2017

Chan-Eng Chong

2

1 reference

7 August 2017

Catherine L Carmichael

3

1 reference

7 August 2017

Ella J Wilkins

4

1 reference

7 August 2017

Peter J Brautigan

5

1 reference

7 August 2017

Xiao-Chun Li

6

1 reference

7 August 2017

Milena Babic

7

1 reference

7 August 2017

Ming Lin

8

1 reference

7 August 2017

Amandine Carmagnac

9

1 reference

7 August 2017

Young K Lee

10

1 reference

7 August 2017

Chung H Kok

11

1 reference

7 August 2017

Lucia Gagliardi

12

1 reference

7 August 2017

Kathryn L Friend

13

1 reference

7 August 2017

Carolyn M Butcher

15

1 reference

7 August 2017

Anna L Brown

16

1 reference

7 August 2017

Ian D Lewis

17

1 reference

7 August 2017

L Bik To

18

1 reference

7 August 2017

Andrew E Timms

19

1 reference

7 August 2017

Jan Storek

20

1 reference

7 August 2017

Sarah Moore

21

1 reference

7 August 2017

Meryl Altree

22

1 reference

7 August 2017

Robert Escher

23

1 reference

7 August 2017

Peter G Bardy

24

1 reference

7 August 2017

Graeme K Suthers

25

1 reference

7 August 2017

Richard J D'Andrea

26

1 reference

7 August 2017

language of work or name

English

0 references

publication date

4 September 2011

1 reference

7 August 2017

1 reference

7 August 2017

volume

43

1 reference

7 August 2017

issue

10

1 reference

7 August 2017

page(s)

1012-1017

1 reference

Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome.

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Myelodysplastic syndromes: a practical approach to diagnosis and treatment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Dominant negative factors in health and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Integrative analysis of RUNX1 downstream pathways and target genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Familial myelodysplasia and acute myeloid leukaemia--a review

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Optimisation of a multipartite human immunodeficiency virus based vector system; control of virus infectivity and large-scale production

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Mutation of GATA3 in human breast tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Potentiation of GATA-2 activity through interactions with the promyelocytic leukemia protein (PML) and the t(15;17)-generated PML-retinoic acid receptor alpha oncoprotein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

An early haematopoietic defect in mice lacking the transcription factor GATA-2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Dermal necrosis and chromosome Iq abnormality in a man with a familial myeloproliferative disorder

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

CBFA2T3-ZNF652 corepressor complex regulates transcription of the E-box gene HEB.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Molecular heterogeneity in AML/MDS patients with 3q21q26 rearrangements.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3184204

Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A.

26 September 2018

1 reference

Emberger syndrome-Primary lymphedema with myelodysplasia: Report of seven new cases

21 January 2018

1 reference

Familial partial monosomy 7 and myelodysplasia

21 January 2018

1 reference

12 December 2020

GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome

1 reference

12 December 2020

A family inheriting different subtypes of acute myelogenous leukemia

1 reference

12 December 2020

Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy

1 reference

12 December 2020

Poor prognosis in familial acute myeloid leukaemia with combined biallelic CEBPA mutations and downstream events affecting the ATM, FLT3 and CDX2 genes

1 reference

12 December 2020

Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency.

1 reference

7 January 2021

inferred from DOI database lookup

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NG.913

1 reference

7 August 2017

1 reference

7 August 2017

1 reference