(Q36043410)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

main subject

gene therapy

0 references

Wiskott-Aldrich syndrome

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Maria Carmina Castiello

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Maria Grazia Roncarolo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Alessandro Aiuti

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Federica Benvenuti

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Anna Villa

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

F Prete

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

M Bosticardo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

E Draghici

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

M Locci

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

22 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

1150-1158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/gt.2011.202

19 January 2020

exact match

0 references

cites work

Stem-cell gene therapy for the Wiskott-Aldrich syndrome

1 reference

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The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets.

2 October 2017

1 reference

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Role of WASP in cell polarity and podosome dynamics of myeloid cells

2 October 2017

1 reference

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Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

2 October 2017

1 reference

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DC subsets in positive and negative regulation of immunity

2 October 2017

1 reference

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WASP: a key immunological multitasker

2 October 2017

1 reference

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Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells

2 October 2017

1 reference

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Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome

2 October 2017

1 reference

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Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models

2 October 2017

1 reference

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WASP and WIP regulate podosomes in migrating leukocytes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

2 October 2017

1 reference

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The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

2 October 2017

1 reference

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Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome

2 October 2017

1 reference

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The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

2 October 2017

The leukocyte podosome

1 reference

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Heterogeneity of thymic dendritic cells

2 October 2017

1 reference

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Close encounters of different kinds: dendritic cells and NK cells take centre stage

2 October 2017

1 reference

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Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

2 October 2017

1 reference

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Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

2 October 2017

1 reference

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In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

2 October 2017

1 reference

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Clinical course of patients with WASP gene mutations

2 October 2017

1 reference

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Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses

2 October 2017

1 reference

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Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

2 October 2017

1 reference

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Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells

2 October 2017

1 reference

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

A 5' regulatory sequence containing two Ets motifs controls the expression of the Wiskott-Aldrich syndrome protein (WASP) gene in human hematopoietic cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells

11 July 2018

1 reference

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Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein

11 July 2018

1 reference

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Mammalian cell expression of dimeric small immune proteins (SIP).

11 July 2018

1 reference

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Results and long-term outcome in 39 patients with Wiskott-Aldrich syndrome transplanted from HLA-matched and -mismatched donors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Expression of Wiskott-Aldrich syndrome protein in dendritic cells regulates synapse formation and activation of naive CD8+ T cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha+ dendritic cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378501

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FGT.2011.202

Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968–99

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FGT.2011.202

Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FGT.2011.202

Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome

21 January 2018

1 reference

12 December 2020

Defective nuclear translocation of nuclear factor of activated T cells and extracellular signal-regulated kinase underlies deficient IL-2 gene expression in Wiskott-Aldrich syndrome

1 reference

12 December 2020

Outcome in patients with Wiskott-Aldrich syndrome following stem cell transplantation: an analysis of 57 patients in Japan

1 reference

12 December 2020

Stem cell transplantation for the Wiskott-Aldrich syndrome: a single-center experience confirms efficacy of matched unrelated donor transplantation

1 reference

12 December 2020

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

1 reference

12 December 2020

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming

1 reference

12 December 2020

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis

1 reference

12 December 2020

Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program

1 reference

12 December 2020

Identifiers

DOI

10.1038/GT.2011.202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22189416%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22189416

1 reference