(Q36045330)

11 August 2017

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title

Evidence from biomarkers and surrogate endpoints (English)

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11 August 2017

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Andrew Feigin

1

1 reference

PMC publication ID

534933

11 August 2017

language of work or name

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1 July 2004

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11 August 2017

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11 August 2017

1

1 reference

11 August 2017

3

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11 August 2017

323-330

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Brain magnetic resonance imaging white-matter lesions and cerebrospinal fluid findings in patients with acute intermittent porphyria

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Cerebrospinal fluid oligoclonal bands in the diagnosis of multiple sclerosis. Isoelectric focusing with IgG immunoblotting compared with high-resolution agarose gel electrophoresis and cerebrospinal fluid IgG index

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

How valid is dopamine transporter imaging as a surrogate marker in research trials in Parkinson's disease?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Surrogate endpoints in Parkinson's disease research

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Advances in the development of biomarkers for Alzheimer's disease: from CSF total tau and Abeta(1-42) proteins to phosphorylated tau protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Annual Incidence of First Silent Stroke in the United States: A Preliminary Estimate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Hypothesis: a single clinical trial plus causal evidence of effectiveness is sufficient for drug approval

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Oxidative stress in Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Surrogate markers as a guide to evaluate response to antiretroviral therapy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Brain CT-scan in acute stroke patients: silent infarcts and relation to outcome.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Alzheimer's disease: beta-Amyloid protein and tau.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Magnetic resonance angiography in acute stroke

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

MRI in the diagnosis and management of multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Total and HDL cholesterol and risk of stroke. EUROSTROKE: a collaborative study among research centres in Europe

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Biological markers to confirm diagnosis and monitor the therapy in multiple sclerosis patients.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Silent MRI infarcts and the risk of future stroke: the cardiovascular health study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Drugs to prevent cell death in Parkinson's disease. Neuroprotection against oxidative stress and inflammatory gene expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Surrogate endpoints and newer risk markers in atherosclerosis management.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Ubiquinone (coenzyme q10) and mitochondria in oxidative stress of parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Cholesterol, stroke risk, and stroke prevention

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Oxidative stress and genetics in the pathogenesis of Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Tolcapone and hepatotoxic effects. Tasmar Advisory Panel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

The role of MR angiography in the evaluation of acute stroke

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Antiglutamate therapies in Huntington's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Huntington's disease: confirmation of diagnosis and presymptomatic testing in Spanish families by genetic analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Oxidative stress and the pathogenesis of Parkinson's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

PET studies on the early and differential diagnosis of Parkinson's disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Differential diagnosis of Parkinson's disease, multiple system atrophy, and Steele-Richardson-Olszewski syndrome: discriminant analysis of striatal 18F-dopa PET data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Huntington's disease, energy, and excitotoxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Molecular diagnostic analysis for Huntington's disease: a prospective evaluation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Glutamate and Huntington's Disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Surrogate endpoints in clinical trials: definition and operational criteria

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Differential diagnosis of Parkinson's disease and the parkinsonism plus syndromes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

CSF oligoclonal bands, MRI, and the diagnosis of multiple sclerosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Issues in Huntington's disease testing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Glutamate in Huntington's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Cerebrospinal Fluid Oligoclonal Bands in the Diagnosis of Multiple Sclerosis

27 July 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

[123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Silent infarcts in stroke patients: patient characteristics and effect on 2-year outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Early differential diagnosis of Parkinson's disease with 18F-fluorodeoxyglucose and positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Tc-99m ethylene cysteinate dimer SPECT in the differential diagnosis of parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

The harsh realities facing the use of SPECT imaging in monitoring disease progression in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Cholesterol and the risk of ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

High-density lipoprotein cholesterol and risk of stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Association study of the 5-HT(6) receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.1.3.323

Association Study of the Interleukin-1beta (C-511T) Genetic Polymorphism with Major Depressive Disorder, Associated Symptomatology, and Antidepressant Response

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Differential diagnosis of Parkinson's disease and vascular parkinsonism by (99m)Tc-TRODAT-1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Tracking of Alzheimer's disease progression with cerebrospinal fluid tau protein phosphorylated at threonine 231.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Usefulness of molecular testing in Huntington's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=534933

Correlations between triplet repeat expansion and clinical features in Huntington's disease

23 September 2018

1 reference

12 December 2020

Radiology quiz. MRI in the diagnosis of multiple sclerosis

1 reference

12 December 2020

Low-Density Lipoprotein Cholesterol and the Risk of Dementia With Stroke

1 reference

12 December 2020

Impact of long-term ECG recording on the detection of paroxysmal atrial fibrillation in patients after an acute ischemic stroke

1 reference

12 December 2020

Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points. Evidence-Based Medicine Working Group

1 reference

12 December 2020

Logistic discriminant parametric mapping: a novel method for the pixel-based differential diagnosis of Parkinson's disease

1 reference

12 December 2020

Surrogate endpoints: the debate goes on

1 reference

12 December 2020

Is multiple sclerosis still a clinical diagnosis?

1 reference

12 December 2020

Contribution of MRI to the diagnosis of multiple sclerosis

1 reference

12 December 2020

The role of complete cerebral angiography in the evaluation of patients with prior stroke

1 reference

12 December 2020

DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Parkinson Study Group

1 reference

12 December 2020

FDA approves clozapine for treatment of schizophrenia; careful monitoring required

1 reference

12 December 2020

Clinical neuromythology IX. Pyramid sale in the bucket shop: DATATOP bottoms out

1 reference

12 December 2020

Surrogate markers in AIDS and cancer trials

1 reference

12 December 2020

Identifiers

DOI

10.1602/NEURORX.1.3.323

1 reference

11 August 2017

1 reference

PMC publication ID

534933

11 August 2017

PubMed publication ID

15717034

1 reference

PMC publication ID

534933