(Q36045952)

11 August 2017

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title

Clinical experience with monoclonal antibodies to epidermal growth factor receptor (English)

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11 August 2017

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Emiliano Calvo

1

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11 August 2017

Eric K Rowinsky

series ordinal

2

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11 August 2017

publication date

1 March 2005

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11 August 2017

published in

Current Oncology Reports

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11 August 2017

volume

7

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11 August 2017

issue

2

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11 August 2017

page(s)

96-103

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Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia

11 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11912-005-0034-9

Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells.

21 January 2018

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12 December 2020

The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors

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12 December 2020

Epithelial growth factor receptor interacting agents

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12 December 2020

The EGF receptor family as targets for cancer therapy

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12 December 2020

Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy

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12 December 2020

Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion

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12 December 2020

Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer

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12 December 2020

Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

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12 December 2020

ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells

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12 December 2020

Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation

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12 December 2020

Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts

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12 December 2020

Targeting the epidermal growth factor receptor

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12 December 2020

Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72 000 in patients with advanced squamous cell carcinoma of the larynx and hypopharynx

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12 December 2020

High levels of HER-2 expression alter the ability of epidermal growth factor receptor (EGFR) family tyrosine kinase inhibitors to inhibit EGFR phosphorylation in vivo

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12 December 2020

Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element

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12 December 2020

Therapeutic potential of ABX-EGF: a fully human anti-epidermal growth factor receptor monoclonal antibody for cancer treatment

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12 December 2020

Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients

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12 December 2020

Influence of unrecognized molecular heterogeneity on randomized clinical trials

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12 December 2020

The erbB family: targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors

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12 December 2020

Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer

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12 December 2020

Anti-(epidermal growth factor) receptor monoclonal antibodies for the induction of antibody-dependent cell-mediated cytotoxicity against squamous cell carcinoma lines of the head and neck

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12 December 2020

Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).

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12 December 2020

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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12 December 2020

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model

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12 December 2020

Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells

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12 December 2020

Targeting HER1/EGFR: a molecular approach to cancer therapy

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12 December 2020

Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody

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12 December 2020

Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor.

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12 December 2020

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

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12 December 2020

Why the epidermal growth factor receptor? The rationale for cancer therapy

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12 December 2020

Biodistribution of 99mTc-labeled anti-human epidermal growth factor receptor (EGF-R) humanized monoclonal antibody h-R3 in a xenograft model of human lung adenocarcinoma

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12 December 2020

Phase I study of the humanized antiepidermal growth factor receptor monoclonal antibody EMD72000 in patients with advanced solid tumors that express the epidermal growth factor receptor

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12 December 2020

Targeting the epidermal growth factor receptor for cancer therapy

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12 December 2020

Erlotinib: preclinical investigations

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12 December 2020

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

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12 December 2020

Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo

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12 December 2020

Pharmacokinetic and pharmacodynamic properties of EGFR inhibitors under clinical investigation.

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12 December 2020

The EGFR as a target for anticancer therapy--focus on cetuximab

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12 December 2020

Targeting the epidermal growth factor receptor: an important incremental step in the battle against colorectal cancer

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12 December 2020

Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor.

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12 December 2020

HER1/EGFR targeting: refining the strategy

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12 December 2020

10.1007/S11912-005-0034-9

Identifiers

DOI

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11 August 2017

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