(Q36048792)

11 August 2017

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title

Drug-induced block of cardiac HERG potassium channels and development of torsade de pointes arrhythmias: the case of antipsychotics (English)

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11 August 2017

Lara Testai

2

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Vincenzo Calderone

object named as

Vincenzo Calderone

1

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author name string

Enrica Martinotti

3

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11 August 2017

Mario Del Tacca

4

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11 August 2017

Maria Cristina Breschi

5

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11 August 2017

publication date

1 February 2005

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Journal of Pharmacy and Pharmacology

11 August 2017

published in

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11 August 2017

volume

57

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11 August 2017

issue

2

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11 August 2017

page(s)

151-161

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In vitro electrophysiological detection of iatrogenic arrhythmogenicity

11 August 2017

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Droperidol: should the black box be light gray?

21 January 2018

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21 January 2018

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21 January 2018

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Transient Cardiac Pacing Is Insufficiently Used to Treat Arrhythmia Associated with Thioridazine

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Pimozide (Orap) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current in native cardiac myocytes

21 January 2018

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Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation

21 January 2018

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[3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen.

21 January 2018

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Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin

21 January 2018

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Death Associated With Ventricular Arrhythmia and Thioridazine Hydrochloride

21 January 2018

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Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death

21 January 2018

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Risperidone prolongs cardiac action potential through reduction of K+ currents in rabbit myocytes

21 January 2018

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The assessment of potential for QT interval prolongation with new pharmaceuticals: impact on drug development

21 January 2018

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Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc.

21 January 2018

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21 January 2018

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Life-Threatening Ventricular Arrhythmia (Torsades de Pointes) after Haloperidol Overdose

21 January 2018

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21 January 2018

Overdose of ziprasidone

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A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs

21 January 2018

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Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication.

21 January 2018

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21 January 2018

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21 January 2018

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Torsade de pointes resulting from the addition of droperidol to an existing cytochrome P450 drug interaction

21 January 2018

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21 January 2018

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Torsades de pointes secondary to intravenous haloperidol after coronary bypass grafting surgery

21 January 2018

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Quetiapine fumarate overdose: clinical and pharmacokinetic lessons from extreme conditions.

21 January 2018

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Fatal cardiac event following initiation of risperidone therapy

21 January 2018

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Torsades de Pointes associated with intravenous haloperidol in critically ill patients

21 January 2018

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Testosterone-mediated modulation of HERG blockade by proarrhythmic agents

21 January 2018

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Tiapride. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in geriatric agitation

21 January 2018

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Proarrhythmic effects of antidepressants and neuroleptic drugs on isolated, spontaneously beating guinea-pig Purkinje fibers

21 January 2018

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A pilot cross-over design study on QTc interval prolongation associated with sulpiride and haloperidol

21 January 2018

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The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

21 January 2018

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21 January 2018

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Torsadegenic action of the antipsychotic drug sulpiride assessed using in vivo canine models

21 January 2018

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Drug-induced torsade de pointes: from molecular biology to bedside.

21 January 2018

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Assessment of coma and impaired consciousness. A practical scale

21 January 2018

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Side effects of ziprasidone

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

The antipsychotic drug chlorpromazine inhibits HERG potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

Electrophysiological safety of sertindole in dogs with normal and remodeled hearts

21 January 2018

1 reference

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In vivo and in vitro myocardial binding of risperidone and 9-hydroxyrisperidone

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

Post-marketing surveillance of sertindole

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

Electrocardiographic changes in patients receiving neuroleptic medication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

Torsade de pointes associated with the use of intravenous haloperidol

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

Comparative study of mortality rates and cardiac dysrhythmias in post-marketing surveillance studies of sertindole and two other atypical antipsychotic drugs, risperidone and olanzapine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

The association between intravenous haloperidol and Torsades de Pointes. Three cases and a literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055272

21 January 2018

Identifiers

DOI

10.1211/0022357055272

1 reference

11 August 2017

1 reference