(Q36051827)

21 June 2018

title

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells (English)

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21 June 2018

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17

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21 June 2018

Xiaoyang Lan

object named as

Xiaoyang Lan

3

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author name string

Sonam Dolma

1

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21 June 2018

Hayden J Selvadurai

2

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21 June 2018

Lilian Lee

4

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21 June 2018

Michelle Kushida

5

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21 June 2018

Veronique Voisin

6

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21 June 2018

Heather Whetstone

7

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21 June 2018

Milly So

8

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21 June 2018

Tzvi Aviv

9

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21 June 2018

Nicole Park

10

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21 June 2018

Xueming Zhu

11

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21 June 2018

ChangJiang Xu

12

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21 June 2018

Renee Head

13

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Katherine J Rowland

14

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21 June 2018

Mark Bernstein

15

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Ian D Clarke

16

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Lea Harrington

18

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John H Brumell

19

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Mike Tyers

20

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Peter B Dirks

21

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21 June 2018

publication date

1 June 2016

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21 June 2018

published in

Cancer Cell

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21 June 2018

volume

29

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21 June 2018

issue

6

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21 June 2018

page(s)

859-873

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21 June 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5968455/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit

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FIP200 is required for maintenance and differentiation of postnatal neural stem cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Amino acid signalling upstream of mTOR

27 July 2018

1 reference

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Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

A restricted cell population propagates glioblastoma growth after chemotherapy

27 July 2018

1 reference

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Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

27 July 2018

1 reference

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Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

27 July 2018

1 reference

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Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity

27 July 2018

1 reference

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Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells

27 July 2018

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The dopamine D4 receptor: biochemical and signalling properties

27 July 2018

1 reference

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Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Neurotransmission and cancer: implications for prevention and therapy

27 July 2018

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Control of cell proliferation by neurotransmitters in the developing vertebrate retina

27 July 2018

1 reference

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

27 July 2018

1 reference

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

27 July 2018

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Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial

27 July 2018

1 reference

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MGMT gene silencing and benefit from temozolomide in glioblastoma

27 July 2018

1 reference

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Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning

27 July 2018

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Dopamine D3 receptor stimulation promotes the proliferation of cells derived from the post-natal subventricular zone

27 July 2018

1 reference

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Identification of human brain tumour initiating cells

27 July 2018

1 reference

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Expression of serotonin receptors and role of serotonin in human prostate cancer tissue and cell lines.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine modulates cell cycle in the lateral ganglionic eminence.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Selective expression of dopamine D3 receptor mRNA in proliferative zones during embryonic development of the rat brain.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Axonal control of the adult neural stem cell niche

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Epigenetic repression of the dopamine receptor D4 in pediatric tumors of the central nervous system

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

The somatic genomic landscape of glioblastoma

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

The role of autophagy in neurodegenerative disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Neurotransmitter-mediated control of neurogenesis in the adult vertebrate brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine D3 receptor activation promotes neural stem/progenitor cell proliferation through AKT and ERK1/2 pathways and expands type-B and -C cells in adult subventricular zone

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Drug combination studies and their synergy quantification using the Chou-Talalay method

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

The dopamine D4 receptor activates intracellular platelet-derived growth factor receptor beta to stimulate ERK1/2.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

New drugs for brain tumors? Insights from chemical probing of neural stem cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Chemical genetics reveals a complex functional ground state of neural stem cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine and adult neurogenesis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Lipid imbalance in the neurological disorder, Niemann-Pick C disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Glutamate as a modulator of embryonic and adult neurogenesis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine depletion impairs precursor cell proliferation in Parkinson disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

Dopamine D(4) and D(2L) Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on trans-Activation of the Platelet-Derived Growth Factor Receptor

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5968455

10.1016/J.CCELL.2016.05.002

23 September 2018

Identifiers

DOI

1 reference

21 June 2018

PMC publication ID

5968455

1 reference

21 June 2018

PubMed publication ID

27300435

1 reference

21 June 2018