(Q36052709)

11 August 2017

1 reference

title

Apoptosis in cerebral ischemia: executional and regulatory signaling mechanisms (English)

1 reference

11 August 2017

1 reference

1 reference

Feng Zhang

1

1 reference

PubMed ID

15727267

11 August 2017

Wei Yin

series ordinal

2

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PubMed ID

15727267

11 August 2017

Jun Chen

series ordinal

3

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11 August 2017

1 December 2004

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11 August 2017

Neurological Research

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11 August 2017

26

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11 August 2017

835-845

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11 August 2017

8

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Programmed cell death in cerebral ischemia

11 August 2017

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Intracellular signal transduction pathways activated by ceramide and its metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

The inhibitors of apoptosis: there is more to life than Bcl2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Inhibition of Daxx-mediated apoptosis by heat shock protein 27

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cytosolic heat shock protein 60, hypoxia, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

PI3K/Akt and apoptosis: size matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Regulation of PTEN transcription by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Phosphatases in apoptosis: to be or not to be, PP2A is in the heart of the question

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

GH prevents apoptosis in cardiomyocytes cultured in vitro through a calcineurin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Mitochondria: releasing power for life and unleashing the machineries of death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Regulation of apoptosis by endoplasmic reticulum pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

A critical role of neural-specific JNK3 for ischemic apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Control of apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Molecular and biochemical features of poly (ADP-ribose) metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

GD3 ganglioside and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Apoptosis and brain ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Prospects for antiapoptotic drug therapy of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Intracellular Bax translocation after transient cerebral ischemia: implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Comparison of calpain and caspase activities in the adult rat brain after transient forebrain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cathepsin B and middle cerebral artery occlusion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Focal cerebral ischemia causes two temporal waves of Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Role of mitogen- and stress-activated kinases in ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Cooperative expression of survival p-ERK and p-Akt signals in rat brain neurons after transient MCAO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Survival- and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome C and Activation of caspase-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Enhanced phosphorylation of PTEN in rat brain after transient middle cerebral artery occlusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Activities of calcineurin and phosphatase 2A in the hippocampus after transient forebrain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Oxidative Damage to the Endoplasmic Reticulum is Implicated in Ischemic Neuronal Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Up-regulation of the Ire1-mediated signaling molecule, Bip, in ischemic rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Ischemic tolerance and endogenous neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

Neuron-specific transgene expression of Bcl-XL but not Bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1179%2F016164104X3824

21 January 2018

Identifiers

DOI

10.1179/016164104X3824

1 reference

11 August 2017

1 reference

PubMed ID

15727267