(Q40591759)

21 September 2017

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils (English)

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21 September 2017

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David A Hildeman

2

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Philippa Marrack

object named as

Philippa Marrack

7

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author name string

Shyra J Gardai

1

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21 September 2017

Steve K Frankel

3

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21 September 2017

Ben B Whitlock

4

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21 September 2017

S Courtney Frasch

5

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21 September 2017

Niels Borregaard

6

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21 September 2017

Donna L Bratton

8

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21 September 2017

Peter M Henson

9

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21 September 2017

language of work or name

English

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publication date

6 February 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

21085-21095

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21 September 2017

20

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To die or not to die: an overview of apoptosis and its role in disease.

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Granulocyte apoptosis and its role in the resolution and control of lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

21 January 2018

The Bcl-2 protein family

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https://api.crossref.org/works/10.1074%2FJBC.M400063200

Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Relative level of expression of Bax and Bcl-XL determines the cellular fate of apoptosis/necrosis induced by the overexpression of Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Purification and biochemical properties of soluble recombinant human Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

CREB is a regulatory target for the protein kinase Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Heterogeneity in the phosphorylation of human death receptors by p42(mapk/erk2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Differential roles for alpha(M)beta(2) integrin clustering or activation in the control of apoptosis via regulation of akt and ERK survival mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Subcellular fractionation of human neutrophils on Percoll density gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Inhibition of TNF-alpha-induced neutrophil apoptosis by crystals of calcium pyrophosphate dihydrate is mediated by the extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways up-stream of caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Molecular control of neutrophil apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400063200

21 January 2018

Identifiers

DOI

10.1074/JBC.M400063200

1 reference

21 September 2017

1 reference