(Q36053763)

11 August 2017

A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients (English)

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11 August 2017

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3

P Ljungman

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11 August 2017

M Hassan

1

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11 August 2017

U S Svensson

2

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11 August 2017

B Björkstrand

4

1 reference

11 August 2017

H Olsson

5

1 reference

11 August 2017

M Bielenstein

6

1 reference

11 August 2017

M Abdel-Rehim

7

1 reference

11 August 2017

C Nilsson

8

1 reference

11 August 2017

M Johansson

9

1 reference

11 August 2017

M O Karlsson

10

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11 August 2017

language of work or name

English

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publication date

1 November 1999

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British Journal of Clinical Pharmacology

11 August 2017

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11 August 2017

48

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11 August 2017

669-677

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11 August 2017

5

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Population pharmacokinetics of methadone in opiate users: characterization of time-dependent changes

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

2 October 2017

Drug metabolite kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Cloning of DNA complementary to cytochrome P-450 induced by pregnenolone-16 alpha-carbonitrile. Characterization of its mRNA, gene, and induction response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Identification of an inducible form of cytochrome P-450 in human liver

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Phenobarbital induction of cytochrome P-450 gene expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Aldehyde dehydrogenases and their role in carcinogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Alkylating properties of phosphoramide mustard

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Turnover of messenger RNA, apoprotein and haem of cytochrome P-450b + e induced by phenobarbitone in rat liver

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Pharmacokinetics of high-dose cyclophosphamide for bone marrow transplantation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

A pharmacodynamic approach to the estimate of carbamazepine autoinduction.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Clinical pharmacokinetics of cyclophosphamide and metabolites with and without SR-2508.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Fluvoxamine Inhibition and Carbamazepine Induction of the Metabolism of Clozapine

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.1999.00090.X

Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014348

Kinetic models of induction: I. Persistence of the inducing substance

5 December 2018

1 reference

12 December 2020

Cytochrome P-450-mediated N-dechloroethylation of cyclophosphamide and ifosfamide in the rat

1 reference

12 December 2020

Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation

1 reference

12 December 2020

Determination of 4-hydroxycyclophosphamide in plasma, as 2,4-dinitrophenylhydrazone derivative of aldophosphamide, by liquid chromatography

1 reference

12 December 2020

Repeated high-dose cyclophosphamide administration in bone marrow transplantation: exposure to activated metabolites

1 reference

12 December 2020

Rapid development of enhanced clearance after high-dose cyclophosphamide

1 reference

12 December 2020

Clinical pharmacokinetics of cyclophosphamide

1 reference

12 December 2020

The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion

1 reference

12 December 2020

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

1 reference

12 December 2020

Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies

1 reference

12 December 2020

Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies

1 reference

12 December 2020

Cyclophosphamide pharmacokinetics in children

1 reference

12 December 2020

Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans

1 reference

12 December 2020

Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes

1 reference

12 December 2020

Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers

1 reference

12 December 2020

Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174

1 reference

12 December 2020

Pharmacokinetics of cyclophosphamide and its metabolites in bone marrow transplantation patients

1 reference

12 December 2020

Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy

1 reference

12 December 2020

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

12 December 2020

Activation of cyclophosphamide in man and animals

1 reference

12 December 2020

Phenobarbital effects on cyclophosphamide pharmacokinetics in man

1 reference

12 December 2020

Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide

1 reference

12 December 2020

Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humans

1 reference

12 December 2020

Kinetics of a carbamazepine-ethosuximide interaction

1 reference

12 December 2020

Metabolism of 4-hydroxycyclophosphamide/aldophosphamide in vitro

1 reference

12 December 2020

PLasma half-life and urinary excretion of cyclophosphamide in children

1 reference

12 December 2020

Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis

1 reference

12 December 2020

Decreased plasma half-life of cyclophosphamide during repeated high-dose administration

1 reference

12 December 2020

Pharmacokinetics of high-dose cyclophosphamide in patients with metastatic bronchogenic carcinoma

1 reference

12 December 2020

High-performance liquid chromatographic measurement of cyclophosphamide in serum

1 reference

12 December 2020

The kinetics of induction by rifampin of alpha 1-acid glycoprotein and antipyrine clearance in the dog

1 reference

12 December 2020

10.1046/J.1365-2125.1999.00090.X

Identifiers

DOI

1 reference

11 August 2017

1 reference

11 August 2017

1 reference