(Q36053982)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Jason M. White

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

A A Somogyi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

K R Dyer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

F Bochner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 November 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Clinical Pharmacology

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

427-440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

A MEDICAL TREATMENT FOR DIACETYLMORPHINE (HEROIN) ADDICTION. A CLINICAL TRIAL WITH METHADONE HYDROCHLORIDE.

1 November 2019

cites work

1 reference

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Population pharmacokinetics of methadone in opiate users: characterization of time-dependent changes

2 October 2017

1 reference

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Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

2 October 2017

1 reference

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The pharmacokinetics of methadone in healthy subjects and opiate users

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Comparing methods of measurements

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Methadone maintenance treatment in opiate dependence: a review.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Methadone binding to orosomucoid (alpha 1-acid glycoprotein): determinant of free fraction in plasma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Fitting straight lines to experimental data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Methadone maintenance: Effect of urinary pH on renal clearance in chronic high and low doses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Binding of disopyramide, methadone, dipyridamole, chlorpromazine, lignocaine and progesterone to the two main genetic variants of human alpha 1-acid glycoprotein: evidence for drug-binding differences between the variants and for the presence of two

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Stereoselective pharmacokinetics of methadone in chronic pain patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Urinary metabolites of DL-methadone in maintenance subjects

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Influence of plasma pH on quinidine uptake by erythrocytes: estimation of free drug fraction in plasma from blood/and erythrocyte/plasma concentration ratios

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Methadone concentrations in plasma and their relationship to drug dosage.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Methadone in man: Pharmacokinetic and excretion studies in acute and chronic treatment

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Stereoselective disposition of methadone in man.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Physical dependence liability of drugs of the methadon series and of 6-methyldihydromorphine.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Pharmacologic comparison of the optical isomers of methadon.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Stereoselective quantification of methadone and its major oxidative metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, in human urine using high-performance liquid chromatography.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

In vitro comparison of cytochrome P450-mediated metabolic activities in human, dog, cat, and horse.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Ultrafiltration using the Amicon MPS-1 for assessing methadone plasma protein binding

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Interaction of methadone with substrates of human hepatic cytochrome P450 3A4.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Steady-state pharmacokinetics of methadone in opioid addicts

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

The erythromycin breath test predicts the clearance of midazolam.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphine

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014413

Replacement of (R)-methadone by a double dose of (R, S)-methadone in addicts: interindividual variability of the (R)/(S) ratios and evidence of adaptive changes in methadone pharmacokinetics

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00272.X

Steady-state pharmacokinetics and pharmacodynamics in methadone maintenance patients: Comparison of those who do and do not experience withdrawal and concentration-effect relationships

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00272.X

Sensitive high-performance liquid chromatographic assay with ultraviolet detection of methadone enantiomers in plasma

21 January 2018

1 reference

12 December 2020

Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes

1 reference

12 December 2020

The efficacy of L-methadone and racemic methadone in substitution treatment for opiate addicts--a double-blind comparison

1 reference

12 December 2020

Enantioselective high-performance liquid chromatography determination of methadone enantiomers and its major metabolite in human biological fluids using a new derivatized cyclodextrin-bonded phase

1 reference

12 December 2020

Disposition of methadone in methadone maintenance

1 reference

12 December 2020

Binding of codeine, morphine, and methadone to human serum proteins

1 reference

12 December 2020

Effects of liver disease on urinary excretion of methadone and metabolites in maintenance patients: quantitation by direct probe chemical ionization mass spectrometry

1 reference

12 December 2020

Quantitation of methadone enantiomers in humans using stable isotope-labeled [2H3]-, [2H5]-, and [2H8]Methadone

1 reference

12 December 2020

Effect of urinary pH on the disposition of methadone in man

1 reference

12 December 2020

Methadone plasma protein binding: alterations in cancer and displacement from alpha 1-acid glycoprotein

1 reference

12 December 2020

Effects of liver disease on fecal excretion of methadone and its unconjugated metabolites in maintenance patients. Quantitation by direct probe chemical ionization mass spectrometry

1 reference

12 December 2020

Altered methadone pharmacokinetics in methadone-maintained pregnant women

1 reference

12 December 2020

Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein

1 reference

12 December 2020

Binding of d-methadone, l-methadone, and dl-methadone to proteins in plasma of healthy volunteers: role of the variants of alpha 1-acid glycoprotein

1 reference

12 December 2020

Chiral analysis of methadone in plasma by high-performance liquid chromatography

1 reference

12 December 2020

Chiral stationary phases in HPLC for the stereoselective determination of methadone

1 reference

12 December 2020

10.1046/J.1365-2125.2000.00272.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11069437%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

11069437

1 reference