(Q36055351)

English

Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

E Störmer

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

I Roots

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

J Brockmöller

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

1 December 2000

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

50

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

553-561

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Flavin monooxygenase 3 (FMO3) polymorphism in a white population: allele frequencies, mutation linkage, and functional effects on clozapine and caffeine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Two novel mutations of the FMO3 gene in a proband with trimethylaminuria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Recent studies on the structure and function of multisubstrate flavin-containing monooxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Multisubstrate flavin-containing monooxygenases: applications of mechanism to specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Role of hepatic flavin-containing monooxygenase 3 in drug and chemical metabolism in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

The molecular biology of the flavin-containing monooxygenases of man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Flavin-containing monooxygenases: catalytic mechanism and substrate specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

2 October 2017

Differences in enzymatic properties of flavin-containing monooxygenase in brain microsomes of rat, mouse, hamster, guinea pig and rabbit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

27 July 2018

Population-specific polymorphisms of the human FMO3 gene: significance for detoxication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

23 September 2018

Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

23 September 2018

Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

23 September 2018

Pharmacokinetics of benzydamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2015007

23 September 2018

Determination of benzydamine and its N-oxide in biological fluids by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotyping of flavin-containing monooxygenase using caffeine metabolism and genotyping of FMO3 gene in a Korean population

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of flavin-containing monooxygenase activity in intact hepatocyte monolayers of rat, hamster, rabbit, dog and human by using N-oxidation of benzydamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay of flavin-containing monooxygenase activity with benzydamine N-oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPLC determination of benzydamine and its metabolite N-oxide in plasma following oral administration or topical application in man, using fluorimetric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11136294

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2125.2000.00296.X

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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