(Q36060026)

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Exploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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Europe PubMed Central

Exploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Elizabeth M. Gillam

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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Elizabeth M J Gillam

1

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Europe PubMed Central

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11 August 2017

publication date

1 March 2005

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Clinical and Experimental Pharmacology and Physiology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

32

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15743395%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

147-152

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9 January 2020

Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs.

1 reference

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21 January 2018

Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil

1 reference

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Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

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Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties

1 reference

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Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution

1 reference

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Random-priming in vitro recombination: an effective tool for directed evolution

1 reference

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Strategies for the in vitro evolution of protein function: enzyme evolution by random recombination of improved sequences

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Molecular evolution by staggered extension process (StEP) in vitro recombination

1 reference

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High efficiency family shuffling based on multi-step PCR and in vivo DNA recombination in yeast: statistical and functional analysis of a combinatorial library between human cytochrome P450 1A1 and 1A2

1 reference

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21 January 2018

Libraries of hybrid proteins from distantly related sequences

1 reference

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General method for sequence-independent site-directed chimeragenesis

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Rapid evolution of a protein in vitro by DNA shuffling

1 reference

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DNA shuffling of a family of genes from diverse species accelerates directed evolution

1 reference

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Recombination and chimeragenesis by in vitro heteroduplex formation and in vivo repair

1 reference

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Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach

1 reference

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Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products

1 reference

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Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase

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High throughput assay for cytochrome P450 BM3 for screening libraries of substrates and combinatorial mutants

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A direct electrode-driven P450 cycle for biocatalysis

1 reference

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A self-sufficient peroxide-driven hydroxylation biocatalyst

1 reference

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21 January 2018

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

1 reference

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21 January 2018

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