(Q36061994)

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Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities

scientific article published on March 1, 1992

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Europe PubMed Central

11 August 2017

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Europe PubMed Central

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Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities (English)

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Europe PubMed Central

11 August 2017

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Greengard P

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Europe PubMed Central

11 August 2017

S. Gandy

1

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Europe PubMed Central

PubMed ID

1574806

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1574806

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10 October 2022

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English

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National Center for Biotechnology Information

PubMed ID

1574806

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1574806

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10 October 2022

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1 March 1992

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Europe PubMed Central

11 August 2017

Trends in Pharmacological Sciences

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Europe PubMed Central

11 August 2017

13

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Europe PubMed Central

11 August 2017

108-113

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Europe PubMed Central

11 August 2017

3

1 reference

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Europe PubMed Central

11 August 2017

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

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Hereditary cerebral hemorrhage with amyloidosis — Dutch type: its importance for Alzheimer research

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Activation of chloride channels in normal and cystic fibrosis airway epithelial cells by multifunctional calcium/calmodulin-dependent protein kinase

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

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Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

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Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

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Amyloid beta protein enhances the survival of hippocampal neurons in vitro

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Deciphering Alzheimer's disease: the amyloid precursor protein yields new clues

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Phosphorylation fails to activate chloride channels from cystic fibrosis airway cells

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

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Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

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Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

1 reference

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RETRACTED ARTICLE: Amyloid plaques, neurofibrillary tangles and neuronal loss in brains of transgenic mice overexpressing a C-terminal fragment of human amyloid precursor protein

1 reference

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Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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Formation of beta-amyloid protein deposits in brains of transgenic mice

1 reference

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Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia

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Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

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Cl- channels in CF: lack of activation by protein kinase C and cAMP-dependent protein kinase

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Alzheimer's mutation.

1 reference

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Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice

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Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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Alzheimer plaques and tangles: advances on both fronts

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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains

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Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease

1 reference

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The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

1 reference

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Familial Alzheimer's disease

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups.

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Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

1 reference

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Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium

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Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

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Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates.

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Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms

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Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

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10.1016/0165-6147(92)90039-9

1 reference

stated in

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

PubMed ID

1574806

retrieved

11 August 2017

(Q36061994)

Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities

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