(Q36063447)

11 August 2017

Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? (English)

1 reference

11 August 2017

1 reference

2

1 reference

11 August 2017

Paula I Moreira

4

0 references

Xiongwei Zhu

series ordinal

3

object named as

Xiongwei Zhu

1 reference

PMCID

3384908

Siddhartha Mondragón-Rodríguez

11 August 2017

series ordinal

1

object named as

Siddhartha Mondragón-Rodríguez

1 reference

11 August 2017

5

Sylvain Williams

1 reference

11 August 2017

14 June 2012

1 reference

International journal of Alzheimer's disease

11 August 2017

1 reference

11 August 2017

2012

1 reference

11 August 2017

276803

1 reference

Creative Commons Attribution 3.0 Unported

11 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Inhibition of GSK3 by Wnt signalling--two contrasting models

1 reference

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The cell biology of synaptic plasticity.

2 October 2017

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Pharmacological treatment of Alzheimer disease

2 October 2017

1 reference

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Neuroprotective action of lithium in disorders of the central nervous system

2 October 2017

1 reference

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Mechanisms of tau self-aggregation and neurotoxicity.

2 October 2017

1 reference

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Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

2 October 2017

1 reference

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Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

2 October 2017

1 reference

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Long-term depression in the CNS.

2 October 2017

1 reference

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Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis

2 October 2017

1 reference

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GSK3: a multifaceted kinase in Wnt signaling

2 October 2017

1 reference

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Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.

2 October 2017

1 reference

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

2 October 2017

1 reference

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Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Association of GSK3B with Alzheimer disease and frontotemporal dementia

2 October 2017

1 reference

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Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

2 October 2017

1 reference

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Synaptic plasticity in learning and memory: stress effects in the hippocampus.

2 October 2017

1 reference

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Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation

2 October 2017

1 reference

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LTP inhibits LTD in the hippocampus via regulation of GSK3beta

2 October 2017

1 reference

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GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt.

2 October 2017

1 reference

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A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions

2 October 2017

1 reference

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Wnt signaling: complexity at the surface.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Tau phosphorylation in neuronal cell function and dysfunction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Tau protein in normal and Alzheimer's disease brain: an update

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

The GSK3 beta signaling cascade and neurodegenerative disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Mood stabilizers, glycogen synthase kinase-3beta and cell survival

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Molecular cloning and expression of glycogen synthase kinase-3/factor A

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384908

Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta

11 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Pseudo-phosphorylation of tau at Ser202 and Thr205 affects tau filament formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Drugs: a tangled web of targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

LTP in hippocampal neurons is associated with a CaMKII-mediated increase in GluA1 surface expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Association analysis of GSK3B and MAPT polymorphisms with Alzheimer's disease in Han Chinese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

Regulation of GSK3 isoforms by phosphatases PP1 and PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F276803

21 January 2018

Identifiers

DOI

10.1155/2012/276803

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

PMCID

3384908