(Q36069228)

12 August 2017

1 reference

title

The elusive function of metallothioneins (English)

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12 August 2017

R D Palmiter

1

1 reference

PMC publication ID

33872

12 August 2017

language of work or name

English

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publication date

1 July 1998

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

95

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12 August 2017

15

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12 August 2017

8428-8430

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Expression of the gene encoding metallothionein-3 in organs of the reproductive system

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Control of zinc transfer between thionein, metallothionein, and zinc proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

The glutathione redox couple modulates zinc transfer from metallothionein to zinc-depleted sorbitol dehydrogenase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Thiolate ligands in metallothionein confer redox activity on zinc clusters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Obesity and hyperleptinemia in metallothionein (-I and -II) null mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Coordination dynamics of biological zinc "clusters" in metallothioneins and in the DNA-binding domain of the transcription factor Gal4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

A murine model of Menkes disease reveals a physiological function of metallothionein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Thinking about genetic redundancy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Constitutive expression of metallothionein-III (MT-III), but not MT-I, inhibits growth when cells become zinc deficient

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Amplification of the metallothionein-I gene in cadmium-resistant mouse cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Molecular biology of metallothionein gene expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Human metallothionein genes: structure of the functional locus at 16q13

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Zinc transfer from transcription factor IIIA fingers to thionein clusters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Metal-regulated transcription in eukaryotes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Glucocorticoid regulation of metallothionein during murine development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Analysis of the detoxification of heavy metal ions by mouse metallothionein.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Endotoxin induction of murine metallothionein gene expression.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Cadmium resistance and content of cadmium-binding protein in two enzyme-deficient mutants of mouse fibroblasts (L-cells)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

Reactivation in vitro of zinc-requiring apo-enzymes by rat liver zinc-thionein

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33872

46 Ligand substitution and sulfhydryl reactivity of metallothionein

23 September 2018

1 reference

12 December 2020

Bioactivity of Metallothionein-3 Correlates with Its Novel .beta. Domain Sequence Rather Than Metal Binding Properties

1 reference

12 December 2020

Transgenic mice that overexpress metallothionein-I resist dietary zinc deficiency

1 reference

12 December 2020

Reversible zinc exchange between metallothionein and the estrogen receptor zinc finger

1 reference

12 December 2020

Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice

1 reference

12 December 2020

Activation of the complete mouse metallothionein gene locus in the maternal deciduum

1 reference

12 December 2020

Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice

1 reference

12 December 2020

A cadmium-resistant variant of the Chinese hamster (CHO) cell with increased metallothionein induction capacity

1 reference

12 December 2020

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

1 reference

12 December 2020

Implications and inferences of metallothionein structure

1 reference

12 December 2020

Induction of hepatic metallothionein by nonmetallic compounds associated with acute-phase response in inflammation

1 reference

12 December 2020

Induction of hepatic metallothionein by paraquat

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.15.8428

1 reference

12 August 2017

0 references

1 reference

PMC publication ID

33872

12 August 2017

PubMed publication ID

9671693

1 reference

PMC publication ID

33872