(Q36072507)

12 August 2017

Pathological significance of mitochondrial glycation (English)

1 reference

12 August 2017

Pamela Boon Li Pun

1

1 reference

PMC publication ID

3388455

12 August 2017

Michael P Murphy

series ordinal

2

1 reference

12 August 2017

21 June 2012

1 reference

International Journal of Cell Biology

12 August 2017

1 reference

12 August 2017

2012

1 reference

12 August 2017

843505

1 reference

Creative Commons Attribution 3.0 Unported

12 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Glyoxalase in diabetes, obesity and related disorders

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2 October 2017

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Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance

2 October 2017

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Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease?

2 October 2017

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Hyperglycemia alters the schwann cell mitochondrial proteome and decreases coupled respiration in the absence of superoxide production

2 October 2017

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Triosephosphate isomerase deficiency: new insights into an enigmatic disease

2 October 2017

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Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates

2 October 2017

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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

2 October 2017

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Advanced glycation endproduct (AGE) accumulation and AGE receptor (RAGE) up-regulation contribute to the onset of diabetic cardiomyopathy

2 October 2017

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Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice.

2 October 2017

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Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells

2 October 2017

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HbA1c: how do we measure it and what does it mean?

2 October 2017

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Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

2 October 2017

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Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.

2 October 2017

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Mitochondria-targeted antioxidants in the treatment of disease

2 October 2017

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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

2 October 2017

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Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

2 October 2017

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Cancer cell metabolism: Warburg and beyond

2 October 2017

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Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease

2 October 2017

1 reference

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Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications

2 October 2017

1 reference

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Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells

2 October 2017

1 reference

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Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

wasted away, a Drosophila mutation in triosephosphate isomerase, causes paralysis, neurodegeneration, and early death

2 October 2017

1 reference

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Mitochondria and cancer: Warburg addressed

2 October 2017

1 reference

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Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification

2 October 2017

1 reference

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Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers

2 October 2017

1 reference

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Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

2 October 2017

1 reference

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Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

2 October 2017

1 reference

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Mitochondria take center stage in aging and neurodegeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Glycation products as markers and predictors of the progression of diabetic complications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

The discovery of glycated hemoglobin: a major event in the study of nonenzymatic chemistry in biological systems

2 October 2017

1 reference

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Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Quantitative screening of protein biomarkers of early glycation, advanced glycation, oxidation and nitrosation in cellular and extracellular proteins by tandem mass spectrometry multiple reaction monitoring

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Glyoxalase I inhibitors in cancer chemotherapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

2 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

2 October 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

The Maillard hypothesis on aging: time to focus on DNA.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Biochemistry and molecular cell biology of diabetic complications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Protein glycation, diabetes, and aging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Synthetically prepared Aamadori-glycated phosphatidylethanolaminecan trigger lipid peroxidation via free radical reactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Oxidative stress and cardiovascular complications in diabetes: isoprostanes as new markers on an old paradigm.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Negative consequences of glycation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

N(2)-(1-Carboxyethyl)deoxyguanosine, a nonenzymatic glycation adduct of DNA, induces single-strand breaks and increases mutation frequencies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Mitochondria in neurodegeneration: bioenergetic function in cell life and death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Glyoxal, a major product of DNA oxidation, induces mutations at G:C sites on a shuttle vector plasmid replicated in mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Nonenzymatic glycation alters protein structure and stability. A study of two eye lens crystallins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Lipid advanced glycosylation: pathway for lipid oxidation in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Role of oxidative stress in development of complications in diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Intracellular glycation of nuclear DNA, mitochondrial DNA, and cytosolic proteins during senescence-like growth arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Mutagenesis and repair induced by the DNA advanced glycation end product N2-1-(carboxyethyl)-2'-deoxyguanosine in human cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Impairment of mitochondrial respiratory chain activity in aortic endothelial cells induced by glycated low-density lipoprotein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Mechanisms of maturation and ageing of collagen

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

DNA modifications by the mutagen glyoxal: adduction to G and C, deamination of C and GC and GA cross-linking.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals--evidence for intracellular lipid glycoxidation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Age-dependent accumulation of advanced glycation end-products in adult Drosophila melanogaster.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Carboxymethylethanolamine, a biomarker of phospholipid modification during the maillard reaction in vivo.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Inhibition of electron flow through complex I of the mitochondrial respiratory chain of Ehrlich ascites carcinoma cells by methylglyoxal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

The metabolism of acetone in rat.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Modification of the glyoxalase system in human red blood cells by glucose in vitro

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

11 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

N2-carboxyethyl-2'-deoxyguanosine, a DNA glycation marker, in kidneys and aortas of diabetic and uremic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

The enzymatic defence against glycation in health, disease and therapeutics: a symposium to examine the concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Use of essential and molecular dynamics to study gammaB-crystallin unfolding after non-enzymic post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Ornithine is a novel amino acid and a marker of arginine damage by oxoaldehydes in senescent proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Identification and quantification of phosphatidylethanolamine-derived glucosylamines and aminoketoses from human erythrocytes--influence of glycation products on lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Analysis of glyoxal-induced DNA cross-links by capillary liquid chromatography nanospray ionization tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Influence of the microenvironment of thiol groups in low molecular mass thiols and serum albumin on the reaction with methylglyoxal

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Degradation of glycated bovine serum albumin in microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

The cytotoxic mechanism of glyoxal involves oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Glycoxidative stress-induced mitophagy modulates mitochondrial fates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Neurodegenerative disease: Diabetes, microvascular pathology and Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

Methylglyoxal, protein binding and biological samples: are we getting the true measure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F843505

The Amadori rearrangement.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388455

Chromatographic evidence for Amadori product formation in rat liver aminophospholipids

23 September 2018

1 reference

12 December 2020

High glucose can induce lipid peroxidation in the isolated rat glomeruli

1 reference

12 December 2020

alpha-Hydroxyaldehydes, products of lipid peroxidation

1 reference

12 December 2020

Isolation and identification of glycated aminophospholipids from red cells and plasma of diabetic blood

1 reference

12 December 2020

Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo

1 reference

12 December 2020

Studies on the life prolonging effect of food restriction: glutathione levels and glyoxalase enzymes in rat liver

1 reference

12 December 2020

Methylglyoxal as substrate and inhibitor of human aldehyde dehydrogenase: comparison of kinetic properties among the three isozymes

1 reference

12 December 2020

DNA-glycation leads to depurination by the loss of N2-carboxyethylguanine in vitro

1 reference

12 December 2020

Effect of collagen turnover on the accumulation of advanced glycation end products

1 reference

12 December 2020

Hepatocyte susceptibility to glyoxal is dependent on cell thiamin content

1 reference

12 December 2020

L-Threonine dehydrogenase from goat liver. Feedback inhibition by methylglyoxal

1 reference

12 December 2020

Mitochondria in cancer

1 reference

12 December 2020

Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation

1 reference

12 December 2020

Protein and low molecular mass thiols as targets and inhibitors of glycation reactions

1 reference

12 December 2020

The autoxidation of glyceraldehyde and other simple monosaccharides under physiological conditions catalysed by buffer ions

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/843505

1 reference

12 August 2017

1 reference

PMC publication ID

3388455

12 August 2017

PubMed publication ID

22778743

1 reference

PMC publication ID

3388455