(Q36073894)

12 August 2017

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title

Mechanistic insight into osteoclast differentiation in osteoimmunology (English)

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12 August 2017

Hiroshi Takayanagi

1

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12 August 2017

publication date

26 January 2005

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Journal of Molecular Medicine

12 August 2017

published in

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12 August 2017

volume

83

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12 August 2017

issue

3

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12 August 2017

page(s)

170-179

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A novel member of the leukocyte receptor complex regulates osteoclast differentiation

12 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS00109-004-0612-6

Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-004-0612-6

Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1

21 January 2018

1 reference

12 December 2020

Impaired differentiation of osteoclasts in TREM-2-deficient individuals

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12 December 2020

Bone versus immune system

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12 December 2020

Transcription factors of the NFAT family: regulation and function

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12 December 2020

Fra-1 replaces c-Fos-dependent functions in mice

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12 December 2020

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts

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12 December 2020

Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos

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12 December 2020

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

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12 December 2020

Osteoclast differentiation and activation

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12 December 2020

Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice

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12 December 2020

Identification of a putative regulator of early T cell activation genes

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12 December 2020

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

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12 December 2020

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

1 reference

12 December 2020

Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1

1 reference

12 December 2020

Murine matrix metalloproteinase 9 gene. 5'-upstream region contains cis-acting elements for expression in osteoclasts and migrating keratinocytes in transgenic mice.

1 reference

12 December 2020

AP-1/jun is required for early Xenopus development and mediates mesoderm induction by fibroblast growth factor but not by activin

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12 December 2020

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

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12 December 2020

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

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12 December 2020

Mechanism of action of a dominant-negative mutant of c-Jun.

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12 December 2020

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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12 December 2020

DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features

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12 December 2020

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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12 December 2020

Arming the osteoclast

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12 December 2020

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms

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12 December 2020

Suppression of oncogene-induced transformation by a deletion mutant of c-jun.

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12 December 2020

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

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12 December 2020

The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase

1 reference

12 December 2020

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

12 December 2020

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1 reference

12 December 2020

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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12 December 2020

Genetic control of skeletal development

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12 December 2020

Natural killer cells, viruses and cancer

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12 December 2020

Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation

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12 December 2020

Roles of Fc receptors in autoimmunity

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12 December 2020

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

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12 December 2020

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1

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12 December 2020

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

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12 December 2020

Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

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12 December 2020

Large scale gene expression analysis of osteoclastogenesis in vitro and elucidation of NFAT2 as a key regulator

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12 December 2020

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

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12 December 2020

Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice

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12 December 2020

Osteoprotegerin deficiency and juvenile Paget's disease

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12 December 2020

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

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12 December 2020

Osteoblastic cells are involved in osteoclast formation.

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12 December 2020

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

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12 December 2020

Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

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12 December 2020

Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis

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12 December 2020

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1.

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12 December 2020

RANK-L and RANK: T cells, bone loss, and mammalian evolution

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12 December 2020

Reaching a genetic and molecular understanding of skeletal development

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12 December 2020

Requirement for NF-kappaB in osteoclast and B-cell development

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12 December 2020

Genetic regulation of osteoclast development and function

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12 December 2020

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

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12 December 2020

Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis

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12 December 2020

Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation

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12 December 2020

Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.

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12 December 2020

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

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12 December 2020

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

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12 December 2020

Interfering with bone remodelling

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12 December 2020

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

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12 December 2020

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

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12 December 2020

NFAT signaling: choreographing the social lives of cells

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12 December 2020

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

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12 December 2020

Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1

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12 December 2020

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β

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12 December 2020

The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites

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12 December 2020

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

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12 December 2020

The tyrosine phosphatase SHP-1 is a negative regulator of osteoclastogenesis and osteoclast resorbing activity: increased resorption and osteopenia in me(v)/me(v) mutant mice

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12 December 2020

Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice

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12 December 2020

Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis

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12 December 2020

The versatility and universality of calcium signalling

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12 December 2020

High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype

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12 December 2020

10.1007/S00109-004-0612-6

Identifiers

DOI

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12 August 2017

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