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Molecular determinants of Gem protein inhibition of P/Q-type Ca2+ channels
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scholarly article
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
title
Molecular determinants of Gem protein inhibition of P/Q-type Ca2+ channels
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
author
Wei Kevin Zhang
series ordinal
2
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
author name string
Mingming Fan
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1
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Zafir Buraei
series ordinal
3
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Jian Yang
series ordinal
4
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
language of work or name
English
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publication date
15 May 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
number of pages
10
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inferred from page(s)
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
287
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
issue
27
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Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
22749-22758
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3391154/fullTextXML
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cites work
The ß subunit of voltage-gated Ca2+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Regulation of calcium channels by RGK proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Direct inhibition of P/Q-type voltage-gated Ca 2+ channels by Gem does not require a direct Gem/Ca v β interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Rem GTPase interacts with the proximal CaV1.2 C-terminus and modulates calcium-dependent channel inactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
RGK GTPase-dependent CaV2.1 Ca2+ channel inhibition is independent of CaVbeta-subunit-induced current potentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Molecular determinants of Rem2 regulation of N-type calcium channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
The RGK family of GTP-binding proteins: regulators of voltage-dependent calcium channels and cytoskeleton remodeling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Genetically encoded molecules for inducibly inactivating CaV channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Plasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
RGK small GTP-binding proteins interact with the nucleotide kinase domain of Ca2+-channel beta-subunits via an uncommon effector binding domain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Biochemical and structural characterization of the gem GTPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Crystal structure of human Rad GTPase of the RGK-family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Nuclear sequestration of beta-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca2+ channel regulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
The RGK family: a regulatory tail of small GTP-binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Molecular regulation of voltage-gated Ca2+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Roles of 14-3-3 and calmodulin binding in subcellular localization and function of the small G-protein Rem2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
14-3-3 and calmodulin control subcellular distribution of Kir/Gem and its regulation of cell shape and calcium channel activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization from down-regulation of calcium channel activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Regulation of Ca2+ channel expression at the cell surface by the small G-protein kir/Gem
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Structure and regulation of voltage-gated Ca2+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391154
retrieved
2 October 2017
Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without affecting channel surface density
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22589533
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nuclear Transport of Kir/Gem Requires Specific Signals and Importin α5 and Is Regulated by Calmodulin and Predicted Serine Phosphorylations
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22589533
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Calmodulin binds to and inhibits GTP binding of the ras-like GTPase Kir/Gem
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22589533
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M111.291872
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMC publication ID
3391154
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
22589533
1 reference
stated in
Europe PubMed Central
PMC publication ID
3391154
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22589533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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