(Q36081610)

English

Structural and functional characterization of H2 haplotype MAPT promoter: unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Structural and functional characterization of H2 haplotype MAPT promoter: unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Alzheimer's disease

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1

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Europe PubMed Central

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22 January 2020

author name string

Debomoy K Lahiri

2

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22 January 2020

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30 January 2012

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22 January 2020

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Europe PubMed Central

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22 January 2020

501

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22 January 2020

1

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22 January 2020

63-78

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22 January 2020

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1 reference

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1 reference

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The world of dementia beyond 2020.

1 reference

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Alzheimer's disease: the challenge of the second century

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Genetic background predicts poor prognosis in frontotemporal lobar degeneration.

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Disease specificity and pathologic progression of tau pathology in brainstem nuclei of Alzheimer's disease and progressive supranuclear palsy

1 reference

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MAPT Isoforms: Differential Transcriptional Profiles Related to 3R and 4R Splice Variants

1 reference

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Tau in Alzheimer disease and related tauopathies

1 reference

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1 reference

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An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.

1 reference

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Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process

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Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells

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The distribution and most recent common ancestor of the 17q21 inversion in humans

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Alzheimer's Disease

1 reference

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Imaging as a strategy for premortem diagnosis and staging of tauopathies

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1 reference

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2 October 2017

Association of the MAPT locus with Parkinson's disease

1 reference

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2 October 2017

Database resources of the National Center for Biotechnology Information

1 reference

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1 reference

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Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice

1 reference

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2 October 2017

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1 reference

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1 reference

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NEANDERTAL GENOMICS: Tales of a Prehistoric Human Genome

1 reference

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Pathological substrates of cognitive decline in Alzheimer's disease

1 reference

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2 October 2017

Evolutionary toggling of the MAPT 17q21.31 inversion region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

Promoter polymorphisms which modulate insulin degrading enzyme expression may increase susceptibility to Alzheimer's disease.

1 reference

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Tau pathology and neurodegeneration: an obvious but misunderstood link.

1 reference

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1 reference

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2 October 2017

Differential regulation of dynein and kinesin motor proteins by tau

1 reference

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2 October 2017

Effect size, confidence interval and statistical significance: a practical guide for biologists

1 reference

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Microcomputers and phylogenetic analysis

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

1 reference

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2 October 2017

Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation

1 reference

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A partial failure of membrane protein turnover may cause Alzheimer's disease: a new hypothesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

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Reelin promoter hypermethylation in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

NF-(kappa)B mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

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A common inversion under selection in Europeans

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2 October 2017

Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

2 October 2017

Tau haplotypes regulate transcription and are associated with Parkinson's disease.

1 reference

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MrBayes 3: Bayesian phylogenetic inference under mixed models

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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2 October 2017

Gaps as characters in sequence-based phylogenetic analyses

1 reference

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TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing

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Efficient DNA transfection in neuronal and astrocytic cell lines

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Electrophoretic mobility shift assay for the detection of specific DNA-protein complex in nuclear extracts from the cultured cells and frozen autopsy human brain tissue

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2 October 2017

Promoter activity of the beta-amyloid precursor protein gene is negatively modulated by an upstream regulatory element

1 reference

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

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Nerve growth factor induces transcription of transforming growth factor-beta 1 through a specific promoter element in PC12 cells

1 reference

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2 October 2017

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

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2 October 2017

Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with tau pathology?

1 reference

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27 July 2018

Gene structure and organization of the human beta-secretase (BACE) promoter.

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27 July 2018

CENSOR--a program for identification and elimination of repetitive elements from DNA sequences

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27 July 2018

An improved sequence assembly program.

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27 July 2018

The promoter activity of the gene encoding Alzheimer β-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences

1 reference

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27 July 2018

Structure and novel exons of the human tau gene

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27 July 2018

2011 Alzheimer's disease facts and figures

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23 September 2018

Dementia risk in Parkinson disease: disentangling the role of MAPT haplotypes

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23 September 2018

Oxidative balance in Alzheimer's disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Disaggregation of tau as a therapeutic approach to tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

The +347 C promoter allele up-regulates MAPT expression and is associated with Alzheimer's disease among the Chinese Han.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Association of the tau haplotype H2 with age at onset and functional alterations of glucose utilization in frontotemporal dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Linkage disequilibrium and haplotype tagging polymorphisms in the Tau H1 haplotype.

1 reference

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23 September 2018

Generalized eta and omega squared statistics: measures of effect size for some common research designs

1 reference

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23 September 2018

Tau protein expression in frontotemporal dementias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

High expression of apolipoprotein E mRNA in the brains with sporadic Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

A tau promoter region without neuronal specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Identification of a tau promoter region mediating tissue-specific-regulated expression in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

23 September 2018

Exploring gene-environment interactions in Parkinson’s disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

21 October 2018

The Effect of MAPT H1 and APOE ε4 on Transition from Mild Cognitive Impairment to Dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391566

5 December 2018

Genomic architecture of human 17q21 linked to frontotemporal dementia uncovers a highly homologous family of low-copy repeats in the tau region

1 reference

https://pubmed.ncbi.nlm.nih.gov/22310385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of insertions, deletions, and alignment errors on the branch-site test of positive selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22310385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using RepeatMasker to identify repetitive elements in genomic sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/22310385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.GENE.2012.01.049

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

release_icg36bqhgfdp7flpsovgw4z2ki

1 reference

https://api.fatcat.wiki/v0/release/icg36bqhgfdp7flpsovgw4z2ki

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22310385%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Sitelinks

Wikipedia(0 entries)

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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