(Q36089515)

12 August 2017

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title

Complex phenotypes and complex genetics: an introduction to genetic studies of complex traits (English)

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12 August 2017

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2

Suzanne M Leal

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12 August 2017

John W Belmont

1

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PubMed ID

15811251

12 August 2017

language of work or name

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1 May 2005

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Current Atherosclerosis Reports

12 August 2017

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12 August 2017

7

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12 August 2017

3

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12 August 2017

180-187

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https://scigraph.springernature.com/pub.10.1007/s11883-005-0004-6

12 August 2017

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cites work

A review of the 'Statistical Analysis for Genetic Epidemiology' (S.A.G.E.) software package

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11883-005-0004-6

Whole genome DNA copy number changes identified by high density oligonucleotide arrays

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11883-005-0004-6

The TDT and other family-based tests for linkage disequilibrium and association

21 January 2018

1 reference

12 December 2020

Multiplex relative risk and estimation of the number of loci underlying an inherited disease

1 reference

12 December 2020

Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis

1 reference

12 December 2020

Multiplexed genotyping with sequence-tagged molecular inversion probes

1 reference

12 December 2020

The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling

1 reference

12 December 2020

Parametric and nonparametric linkage analysis: a unified multipoint approach

1 reference

12 December 2020

Organizational challenges in clinical genomic research

1 reference

12 December 2020

The family based association test method: strategies for studying general genotype--phenotype associations.

1 reference

12 December 2020

Estimating recombination rates from population-genetic data

1 reference

12 December 2020

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

1 reference

12 December 2020

The allelic architecture of human disease genes: common disease-common variant... or not?

1 reference

12 December 2020

Mismatch repair detection (MRD): high-throughput scanning for DNA variations

1 reference

12 December 2020

Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites

1 reference

12 December 2020

Linkage analysis in nuclear families. 1: Optimality criteria for affected sib-pair tests

1 reference

12 December 2020

The fine-scale structure of recombination rate variation in the human genome

1 reference

12 December 2020

BAC microarray-based comparative genomic hybridization

1 reference

12 December 2020

The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping

1 reference

12 December 2020

Association mapping in structured populations

1 reference

12 December 2020

Use of sibling risk ratios and components of genetic variance in the characterization of a simulated oligogenic disease

1 reference

12 December 2020

Whole-genome patterns of common DNA variation in three human populations

1 reference

12 December 2020

Linkage strategies for genetically complex traits. II. The power of affected relative pairs

1 reference

12 December 2020

Review of assumptions and problems in the appropriate conceptualization of effect size

1 reference

12 December 2020

Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics

1 reference

12 December 2020

The endophenotype concept in psychiatry: etymology and strategic intentions

1 reference

12 December 2020

The structure of haplotype blocks in the human genome

1 reference

12 December 2020

Large-scale copy number polymorphism in the human genome

1 reference

12 December 2020

The power to detect linkage disequilibrium with quantitative traits in selected samples

1 reference

12 December 2020

Admixture mapping for hypertension loci with genome-scan markers

1 reference

12 December 2020

Allelic imbalance analysis by high-density single-nucleotide polymorphic allele (SNP) array with whole genome amplified DNA.

1 reference

12 December 2020

Variance component methods for detecting complex trait loci

1 reference

12 December 2020

In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice

1 reference

12 December 2020

Sib-pair collection strategies for complex diseases

1 reference

12 December 2020

Assessing the performance of the haplotype block model of linkage disequilibrium

1 reference

12 December 2020

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)

1 reference

12 December 2020

Population stratification and spurious allelic association

1 reference

12 December 2020

Allele-sharing models: LOD scores and accurate linkage tests

1 reference

12 December 2020

A High-Density Admixture Map for Disease Gene Discovery in African Americans

1 reference

12 December 2020

The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits

1 reference

12 December 2020

Linkage analysis in nuclear families. 2: Relationship between affected sib-pair tests and lod score analysis

1 reference

12 December 2020

Genetics of quantitative variation in human gene expression

1 reference

12 December 2020

Mathematical assumptions versus biological reality: myths in affected sib pair linkage analysis

1 reference

12 December 2020

BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping

1 reference

12 December 2020

Merlin--rapid analysis of dense genetic maps using sparse gene flow trees

1 reference

12 December 2020

Association analysis in a variance components framework

1 reference

12 December 2020

Multipoint quantitative-trait linkage analysis in general pedigrees

1 reference

12 December 2020

Testing for population subdivision and association in four case-control studies

1 reference

12 December 2020

Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design.

1 reference

12 December 2020

Assessing the impact of population stratification on genetic association studies

1 reference

12 December 2020

Genomic Priorities and Public Health

1 reference

12 December 2020

A tournament of linkage tests in complex inheritance.

1 reference

12 December 2020

Haplotype blocks and linkage disequilibrium in the human genome

1 reference

12 December 2020

Statistical tests for admixture mapping with case-control and cases-only data

1 reference

12 December 2020

Human genome sequence variation and the influence of gene history, mutation and recombination

1 reference

12 December 2020

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

1 reference

12 December 2020

Association study designs for complex diseases

1 reference

12 December 2020

General models for segregation analysis

1 reference

12 December 2020

A tiling resolution DNA microarray with complete coverage of the human genome

1 reference

12 December 2020

Linkage and association

1 reference

12 December 2020

Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility Loci

1 reference

12 December 2020

Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps

1 reference

12 December 2020

Mapping quantitative trait loci in the case of a spike in the phenotype distribution.

1 reference

12 December 2020

Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies.

1 reference

12 December 2020

Concurrent analysis of loss of heterozygosity (LOH) and copy number abnormality (CNA) for oral premalignancy progression using the Affymetrix 10K SNP mapping array

1 reference

12 December 2020

Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay

1 reference

12 December 2020

The effects of human population structure on large genetic association studies

1 reference

12 December 2020

Complete multipoint sib-pair analysis of qualitative and quantitative traits

1 reference

12 December 2020

Linkage strategies for genetically complex traits. I. Multilocus models

1 reference

12 December 2020

Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations

1 reference

12 December 2020

A comparison of sib-pair linkage tests for disease susceptibility loci

1 reference

12 December 2020

Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families

1 reference

12 December 2020

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

1 reference

12 December 2020

The Distribution of Long Range Admixture Linkage Disequilibrium in an African-American Population

1 reference

12 December 2020

High-resolution haplotype structure in the human genome

1 reference

12 December 2020

Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation

1 reference

12 December 2020

Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations

1 reference

12 December 2020

The International HapMap Project

1 reference

12 December 2020

The complex interplay among factors that influence allelic association.

1 reference

12 December 2020

Large-scale genotyping of complex DNA.

1 reference

12 December 2020

Case-control studies of association in structured or admixed populations.

1 reference

12 December 2020

10.1007/S11883-005-0004-6

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

15811251