(Q36104835)

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The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

uterine cervix neoplasm

1 reference

based on heuristic

inferred from title

author name string

Prashanthi Javvadi

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Andrew T Segan

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Stephen W Tuttle

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Constantinos Koumenis

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

5 February 2008

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

73

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1491-1501

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3400533/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Radiation-induced cell signaling: inside-out and outside-in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Radiation-induced PARP activation is enhanced through EGFR-ERK signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

The concurrent chemoradiation paradigm--general principles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Reactive oxygen species-induced activation of the MAP kinase signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Radiosensitizers in cervical cancer. Cisplatin and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Increased expression of pAKT is associated with radiation resistance in cervical cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Dose escalation of a curcuminoid formulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Chemopreventive and therapeutic effects of curcumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin: a new radio-sensitizer of squamous cell carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Nuclear factor-kappaB: the enemy within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Phosphatidylinositide 3-kinase/AKT in radiation responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

A systematic review of acute and late toxicity of concomitant chemoradiation for cervical cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

MAPK pathways in radiation responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Mitogen-activated protein kinases and their role in regulation of cellular processes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Epidermal growth factor family receptors and inhibitors: radiation response modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Cancer chemoprevention by dietary constituents: a tale of failure and promise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Putative mechanism for anticancer and apoptosis-inducing properties of plant-derived polyphenolic compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Requirement for ERK activation in cisplatin-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Persistent oxidative stress in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 October 2017

Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 July 2018

Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

2 July 2018

Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubule epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.

1 reference

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23 September 2018

Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400533

23 September 2018

Lack of involvement of ataxia telangiectasia mutated (ATM) in regulation of nuclear factor-kappaB (NF-kappaB) in human diploid fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SYNTHESIS OF DIACETYLDICHLOROFLUORESCIN: A STABLE REAGENT FOR FLUOROMETRIC ANALYSIS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase as a target for the selective killing of cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.107.043554

1 reference

https://api.fatcat.wiki/v0/release/7isjs6pw2ngtjpzrwbfbof4wha

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_7isjs6pw2ngtjpzrwbfbof4wha

1 reference

https://api.fatcat.wiki/v0/release/7isjs6pw2ngtjpzrwbfbof4wha

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/7isjs6pw2ngtjpzrwbfbof4wha

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/7isjs6pw2ngtjpzrwbfbof4wha

30 July 2022

based on heuristic

mapped directly with Wikidata item

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