(Q36105767)

12 August 2017

1 reference

title

Muscarinic receptor subtype pharmacology and physiology (English)

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12 August 2017

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Richard M Eglen

1

1 reference

12 August 2017

1 January 2005

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Progress in medicinal chemistry

12 August 2017

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12 August 2017

43

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12 August 2017

105-136

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Muscarinic receptors--characterization, coupling and function

12 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Therapeutic opportunities for muscarinic receptors in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic receptor ligands and their therapeutic potential

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Selective muscarinic receptor agonists and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Direct binding studies on ileal and cardiac muscarinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Molecular biology of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

M1-M5 muscarinic receptor knockout mice as novel tools to study the physiological roles of the muscarinic cholinergic system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Tolterodine: selectivity for the urinary bladder over the eye (as measured by visual accommodation) in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Structure and activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-o

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Monomers and oligomers of the M2 muscarinic cholinergic receptor purified from Sf9 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The paired activation of the two components of the muscarinic M3 receptor dimer is required for induction of ERK1/2 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Site of Action of the General Anesthetic Propofol in Muscarinic M1 Receptor-Mediated Signal Transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Cellular signaling mechanisms for muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic regulation of cardiac ion channels

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The anti-apoptotic response of the Gq/11-coupled muscarinic receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

M<sub>1</sub> Muscarinic Agonists Can Modulate Some of the Hallmarks in Alzheimer's Disease: Implications in Future Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The cholinergic hypothesis of geriatric memory dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Treatment of dementia with neurotransmission modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Novel insights into muscarinic acetylcholine receptor function using gene targeting technology

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Activation of muscarinic receptors inhibits beta-amyloid peptide-induced signaling in cortical slices.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Impact of muscarinic agonists for successful therapy of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Neuroprotective strategies in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Xanomeline and the antipsychotic potential of muscarinic receptor subtype selective agonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Discovery of an ectopic activation site on the M(1) muscarinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Association of muscarinic m1 receptor genetic polymorphisms with psychiatric symptoms and cognitive function in schizophrenic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl- d -aspartate receptor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Acetylcholine synthesis and muscarinic receptor subtype mRNA expression in T-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Roles of muscarinic acetylcholine receptors in interleukin-2 synthesis in lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic cholinergic receptors on intact human lymphocytes. Properties and subclass characterization.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Immunochemical and immunocytochemical characterization of cholinergic markers in human peripheral blood lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The presence and functions of muscarinic receptors in human T cells: the involvement in IL-2 and IL-2 receptor system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Role of the cholinergic muscarinic 2 receptor (CHRM2) gene in cognition.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Long-term effects of BIBN-99, a selective muscarinic M2 receptor antagonist, on improving spatial memory performance in aged cognitively impaired rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Intrastriatal infusions of methoctramine improve memory in cognitively impaired aged rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Cholinergic drugs in pharmacotherapy of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane .

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Cortisol, stress and depression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic agonist-mediated increases in serum corticosterone levels are abolished in m(2) muscarinic acetylcholine receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic inhibition of single KCa channels in smooth muscle cells by a pertussis-sensitive G protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The M2 muscarinic G-protein-coupled receptor is voltage-sensitive

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Changes in morphology and inward rectifier currents in human atrial myocytes depend on culture conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Human chagasic IgGs bind to cardiac muscarinic receptors and impair L-type Ca2+ currents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Relationship of myocardial remodeling to the genesis of serum autoantibodies to cardiac beta(1)-adrenoceptors and muscarinic type 2 acetylcholine receptors in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Cruzipain induces autoantibodies against cardiac muscarinic acetylcholine receptors. Functional and pathological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Structure/activity relationships of M2 muscarinic allosteric modulators

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

A model of the human M2 muscarinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Demonstration of functional M3-muscarinic receptors in ventricular cardiomyocytes of adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Differential alterations of receptor densities of three muscarinic acetylcholine receptor subtypes and current densities of the corresponding K+ channels in canine atria with atrial fibrillation induced by experimental congestive heart failure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Contractile role of M2 and M3 muscarinic receptors in gastrointestinal, airway and urinary bladder smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Development of ovine fetal ileal motility: role of muscarinic receptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Gender comparison of muscarinic receptor expression and function in rat and human urinary bladder: differential regulation of M2 and M3 receptors?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic receptor subtypes in the human colon: lack of evidence for atypical subtypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

G-protein-gated TRP-like cationic channel activated by muscarinic receptors: effect of potential on single-channel gating

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic agonist potencies at three different effector systems linked to the M(2) or M(3) receptor in longitudinal smooth muscle of guinea-pig small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Phospholipase C, but not InsP3 or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Pharmacological analysis of the contractile role of M2 and M3 muscarinic receptors in smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

M(3)-receptor knockout mice: muscarinic receptor function in atria, stomach fundus, urinary bladder, and trachea

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Tolterodine--a new bladder selective muscarinic receptor antagonist: preclinical pharmacological and clinical data

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Pharmacological Effects of Darifenacin on Human Isolated Urinary Bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Retrospective analysis of efficacy and tolerability of tolterodine in children with overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic receptor antagonists in the treatment of overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Randomized, double-blind placebo- and tolterodine-controlled trial of the once-daily antimuscarinic agent solifenacin in patients with symptomatic overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Update on overactive bladder: Pharmacologic approaches on the horizon

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Trospium chloride: A quaternary amine with unique pharmacologic properties

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic receptors of the urinary bladder: detrusor, urothelial and prejunctional.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Irritable bowel syndrome neuropharmacology. A review of approved and investigational compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Otilonium bromide inhibits muscle contractions via L-type calcium channels in the rat colon.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Tolterodine use for symptoms of overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Role of muscarinic receptor subtypes in the constriction of peripheral airways: studies on receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

A Mechanism for Rapacuronium-induced Bronchospasm

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Eosinophil and airway nerve interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic Receptor Agonists and Antagonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Tiotropium bromide: a novel once-daily anticholinergic bronchodilator for the treatment of COPD.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Pharmacologic Treatment of Chronic Obstructive Pulmonary Disease: Past, Present, and Future

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

1 reference

7 January 2021

Development of selective antisera for muscarinic cholinergic receptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: a study with M2- and M4-receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic M2 receptors on peripheral nerve endings: a molecular target of antinociception.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Localization of m5 muscarinic receptor mRNA in rat brain examined by in situ hybridization histochemistry.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

The muscarinic M(5) receptor: a silent or emerging subtype?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Functional acetylcholine muscarinic receptor subtypes in human brain microcirculation: identification and cellular localization.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Muscarinic--but not nicotinic--acetylcholine receptors mediate a nitric oxide-dependent dilation in brain cortical arterioles: a possible role for the M5 receptor subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Localization of the m5 muscarinic cholinergic receptor in rat circle of Willis and pial arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Cholinergic dilation of cerebral blood vessels is abolished in M(5) muscarinic acetylcholine receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Increased drinking in mutant mice with truncated M5 muscarinic receptor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

Functional selectivity of muscarinic receptor antagonists for inhibition of M3-mediated phosphoinositide responses in guinea pig urinary bladder and submandibular salivary gland.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2805%2943004-0

7 January 2021

10.1016/S0079-6468(05)43004-0

Identifiers

DOI

1 reference

release_42zvmf4wgrge3kaltb2jwrgzuq

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/42zvmf4wgrge3kaltb2jwrgzuq

24 November 2022

mapped directly with Wikidata item

PubMed ID

15850824

1 reference

PubMed ID

15850824