(Q36108056)

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Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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author name string

Joshua P Fessel

1

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Europe PubMed Central

PMC publication ID

12 August 2017

Rizwan Hamid

2

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12 August 2017

Bryan M Wittmann

3

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Europe PubMed Central

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12 August 2017

Linda J Robinson

4

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12 August 2017

Tom Blackwell

5

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12 August 2017

Yuji Tada

6

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Europe PubMed Central

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12 August 2017

Nobuhiro Tanabe

7

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12 August 2017

Koichiro Tatsumi

8

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12 August 2017

Anna R Hemnes

9

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12 August 2017

James D West

10

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12 August 2017

publication date

1 April 2012

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12 August 2017

Pulmonary circulation

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12 August 2017

2

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Europe PubMed Central

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12 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

201-213

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Europe PubMed Central

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12 August 2017

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1 reference

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1 reference

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1 reference

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1 reference

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Oxidative injury is a common consequence of BMPR2 mutations

1 reference

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1 reference

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Physiologic and molecular consequences of endothelial Bmpr2 mutation

1 reference

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1 reference

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Unrecognized glucose intolerance is common in pulmonary arterial hypertension

1 reference

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Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome

1 reference

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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

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Organization of GC/MS and LC/MS metabolomics data into chemical libraries

1 reference

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Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure

1 reference

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Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

1 reference

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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension

1 reference

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Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells

1 reference

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1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

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Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension

1 reference

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IDH1 and IDH2 mutations in gliomas

1 reference

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

1 reference

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Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

1 reference

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Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

1 reference

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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

1 reference

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Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-alpha and anticancer drugs

1 reference

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Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

1 reference

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Establishment and characterization of Fabry disease endothelial cells with an extended lifespan.

1 reference

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Alterations of cellular bioenergetics in pulmonary artery endothelial cells

1 reference

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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

1 reference

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Maintenance of differentiation potential of human bone marrow mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene despite [corrected] extensive proliferation.

1 reference

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Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis

1 reference

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Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Primary pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22837861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22837861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial NADPH, transhydrogenase and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22837861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22837861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4103/2045-8932.97606

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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