(Q35215557)

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The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

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scholarly article

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Europe PubMed Central

7 August 2017

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels (English)

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Europe PubMed Central

7 August 2017

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10

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Benoit Viollet

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Europe PubMed Central

7 August 2017

Suh Young Jeong

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Suh Young Jeong

4

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Rachid Sougrat

8

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13

object named as

Jane Trepel

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7 August 2017

Carole Sourbier

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Carole Sourbier

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Europe PubMed Central

7 August 2017

William Linehan

17

object named as

W Marston Linehan

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7 August 2017

author name string

Wing-Hang Tong

1

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7 August 2017

Gennady Kovtunovych

3

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7 August 2017

Manish Vira

5

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Europe PubMed Central

7 August 2017

Manik Ghosh

6

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Europe PubMed Central

7 August 2017

Vladimir Valera Romero

7

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7 August 2017

Sophie Vaulont

9

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Europe PubMed Central

7 August 2017

Yeong-Sang Kim

11

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Europe PubMed Central

7 August 2017

Sunmin Lee

12

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Europe PubMed Central

7 August 2017

Ramaprasad Srinivasan

14

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7 August 2017

Gennady Bratslavsky

15

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7 August 2017

Youfeng Yang

16

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7 August 2017

Tracey A Rouault

18

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7 August 2017

publication date

1 September 2011

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7 August 2017

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7 August 2017

20

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7 August 2017

3

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7 August 2017

315-327

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7 August 2017

describes a project that uses

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Hypoxic regulation of erythropoiesis and iron metabolism

1 reference

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Tumorigenic properties of iron regulatory protein 2 (IRP2) mediated by its specific 73-amino acids insert

1 reference

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Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree?

1 reference

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13 July 2018

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

1 reference

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13 July 2018

p53 and metabolism

1 reference

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1 reference

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Histological evaluation of AMPK signalling in primary breast cancer

1 reference

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SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma

1 reference

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Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

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1 reference

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Tumor suppressors and cell metabolism: a recipe for cancer growth

1 reference

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Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

1 reference

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Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing

1 reference

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Post-transcriptional modulation of iron homeostasis during p53-dependent growth arrest

1 reference

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13 July 2018

Cooperation of two mRNA-binding proteins drives metabolic adaptation to iron deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

1 reference

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

1 reference

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Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

1 reference

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

1 reference

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

1 reference

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Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

1 reference

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Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

Hypoxia-inducible factors: central regulators of the tumor phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

The role of iron regulatory proteins in mammalian iron homeostasis and disease

1 reference

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5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

Divalent metal transporter 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

13 July 2018

Crystal structure of mitochondrial respiratory membrane protein complex II

1 reference

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Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

1 reference

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13 July 2018

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

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Metformin and reduced risk of cancer in diabetic patients

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AMPK, the metabolic syndrome and cancer

1 reference

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AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms

1 reference

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Akt stimulates aerobic glycolysis in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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On the Origin of Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3174047

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AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1016/J.CCR.2011.07.018

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Europe PubMed Central

7 August 2017

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Europe PubMed Central

7 August 2017

1 reference

Europe PubMed Central

7 August 2017

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