(Q29617084)

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p53 and metabolism

scientific article (publication date: October 2009)

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p53 and metabolism (English)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

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ORCID Public Data File 2021

author name string

Vousden KH

1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

Ryan KM

2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

language of work or name

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

publication date

October 2009

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

Nature Reviews Cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

9

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

691-700

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

On the Origin of Cancer Cells

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Metabolic transformation in cancer.

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Tumor cell metabolism: cancer's Achilles' heel

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31 March 2020

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

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31 March 2020

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

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31 March 2020

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

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31 March 2020

Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.

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31 March 2020

Hypoxia, HIF1 and glucose metabolism in the solid tumour

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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Exploiting the PI3K/AKT pathway for cancer drug discovery

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31 March 2020

The interplay between MYC and HIF in cancer.

1 reference

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31 March 2020

Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

1 reference

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31 March 2020

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

1 reference

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31 March 2020

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

1 reference

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31 March 2020

Coping with stress: multiple ways to activate p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Blinded by the Light: The Growing Complexity of p53

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Regulation of PTEN transcription by p53

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Activation of AMP-activated protein kinase induces p53-dependent apoptotic cell death in response to energetic stress

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

An ATP/ADP-dependent molecular switch regulates the stability of p53-DNA complexes.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The PP2A-associated protein alpha4 is an essential inhibitor of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Hypoxia links ATR and p53 through replication arrest

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Putting a finger on growth surveillance: insight into MDM2 zinc finger-ribosomal protein interactions.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Redox signalling and transition metals in the control of the p53 pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulates mtDNA copy number and mitocheckpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulates mitochondrial respiration

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The coordinate regulation of the p53 and mTOR pathways in cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Autophagosome formation: core machinery and adaptations

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Development by self-digestion: molecular mechanisms and biological functions of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Autophagy in metazoans: cell survival in the land of plenty

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Role of autophagy in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Autophagy mediates the mitotic senescence transition

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53-Dependent and p53-independent activation of autophagy by ARF

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Regulation of autophagy by cytoplasmic p53

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Control of autophagy by oncogenes and tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

PUMA- and Bax-induced autophagy contributes to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Stimulation of autophagy by the p53 target gene Sestrin2.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Mutant p53 protein localized in the cytoplasm inhibits autophagy

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The ARF/p53 pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

ARF induces autophagy by virtue of interaction with Bcl-xl.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The antioxidant function of the p53 tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Transcriptional activation of the human glutathione peroxidase promoter by p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Tumor protein 53-induced nuclear protein 1 is a major mediator of p53 antioxidant function

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Discovery of novel tumor suppressor p53 response elements using information theory

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Reciprocal down-regulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53-induced up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 suppresses the Nrf2-dependent transcription of antioxidant response genes.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Tumor suppressors and cell metabolism: a recipe for cancer growth

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The dark side of a tumor suppressor: anti-apoptotic p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Germline TP53 mutations and Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

TP53 status and response to chemotherapy in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Antagonistic pleiotropy and p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The tumor suppressor p53: cancer and aging

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The Arf/p53 pathway in cancer and aging

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulation orchestrates the TGF-beta response

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 in embryonic development: maintaining a fine balance

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 suppresses the self-renewal of adult neural stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulates hematopoietic stem cell quiescence.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 regulates maternal reproduction through LIF

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Central role of p53 in the suntan response and pathologic hyperpigmentation

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Molecular insights into mechanisms of the cell death program: role in the progression of neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Chemoprotection from p53-dependent apoptosis: potential clinical applications of the p53 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Pifithrin-alpha attenuates p53-mediated apoptosis and improves cardiac function in response to myocardial ischemia/reperfusion in aged rats.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Apoptosis in ischemic renal injury: roles of GTP depletion and p53.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

The role of p53 in neuronal cell death

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Nucleolus, ribosomes, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

1 reference

https://api.crossref.org/works/10.1038%2FNRC2715

31 March 2020

Sugar and fat - that's where it's at: metabolic changes in tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 is a transcriptional activator of the muscle-specific phosphoglycerate mutase gene and contributes in vivo to the control of its cardiac expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A crucial role for adipose tissue p53 in the regulation of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycolytic enzymes can modulate cellular life span

1 reference

https://pubmed.ncbi.nlm.nih.gov/19759539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NRC2715

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=19759539

30 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Springer Nature article ID

10.1038/nrc2715

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