(Q36112585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Charles Kunos

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Fadi W Abdul-Karim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

James Fanning

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Ovadia Abulafia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Albert J Bonebrake

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Lydia Usha

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

publication date

27 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

Journal of Translational Medicine

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

30 January 2020

copyright license

start time

27 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1479-5876-10-79

0 references

cites work

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study

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Deoxynucleoside salvage facilitates DNA repair during ribonucleotide reductase blockade in human cervical cancers

2 October 2017

1 reference

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Ribonucleotide reductase inhibition enhances chemoradiosensitivity of human cervical cancers

2 October 2017

1 reference

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Phase I trial of pelvic radiation, weekly cisplatin, and 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) for locally advanced cervical cancer

2 October 2017

1 reference

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Modulating radiation resistance by inhibiting ribonucleotide reductase in cancers with virally or mutationally silenced p53 protein

2 October 2017

1 reference

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Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins

2 October 2017

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A phase II trial of triapine (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503

2 October 2017

1 reference

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A phase I study of Triapine in combination with doxorubicin in patients with advanced solid tumors

2 October 2017

1 reference

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Methemoglobinemia: from diagnosis to treatment

2 October 2017

1 reference

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Kinetics of H2AX phosphorylation after exposure to cisplatin

2 October 2017

1 reference

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A phase II study of cisplatin preceded by a 12-h continuous infusion of concurrent hydroxyurea and cytosine arabinoside (Ara-C) for adult patients with malignant gliomas (Southwest Oncology Group S9149)

2 October 2017

1 reference

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Phase II study of gemcitabine combined with platinum chemotherapy for recurrent epithelial ovarian cancer.

2 October 2017

1 reference

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Proton-coupled electron transfer: the mechanistic underpinning for radical transport and catalysis in biology

2 October 2017

1 reference

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Cellular processing of platinum anticancer drugs

2 October 2017

1 reference

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Phosphorylation of histone H2AX as a measure of radiosensitivity

2 October 2017

1 reference

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Phase I and pharmacokinetic study of triapine, a potent ribonucleotide reductase inhibitor, administered daily for five days in patients with advanced solid tumors

2 October 2017

1 reference

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Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Cisplatin, doxorubicin and paclitaxel induce mdr1 gene transcription in ovarian cancer cell lines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Phase I and pharmacokinetic study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) using a single intravenous dose schedule

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Concise review: methemoglobinemia

2 October 2017

1 reference

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Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Hydroxyurea or placebo combined with radiation to treat stages iiib and iv cervical cancer confined to the pelvis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks

2 October 2017

1 reference

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Intraperitoneal cisplatin and paclitaxel in ovarian cancer.

2 July 2018

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Phase III trial of carboplatin plus paclitaxel with or without gemcitabine in first-line treatment of epithelial ovarian cancer

21 January 2018

1 reference

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Cisplatin plus gemcitabine in platinum-refractory ovarian or primary peritoneal cancer: a phase II study of the Gynecologic Oncology Group

21 January 2018

1 reference

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Phase I and pharmacokinetic study of the ribonucleotide reductase inhibitor, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, administered by 96-hour intravenous continuous infusion

21 January 2018

1 reference

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A phase I trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in combination with gemcitabine for patients with advanced cancer

21 January 2018

1 reference

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Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403898

Combination chemotherapy with carboplatin and docetaxel in the treatment of cancers of the ovary and fallopian tube and primary carcinoma of the peritoneum

23 September 2018

1 reference

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Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group stud

23 September 2018

1 reference

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Long-term follow-up of a randomized trial comparing concurrent single agent cisplatin, cisplatin-based combination chemotherapy, or hydroxyurea during pelvic irradiation for locally advanced cervical cancer: a Gynecologic Oncology Group Study

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22541066

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A phase I study of gemcitabine followed by cisplatin concurrent with whole pelvic radiation therapy in locally advanced cervical cancer: a Gynecologic Oncology Group study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22541066

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase III, open-label, randomized study comparing concurrent gemcitabine plus cisplatin and radiation followed by adjuvant gemcitabine and cisplatin versus concurrent cisplatin and radiation in patients with stage IIB to IVA carcinoma of the cervix

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22541066

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1479-5876-10-79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22541066%20AND%20SRC:MED&resulttype=core&format=json