(Q39466509)

English

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study

scientific article published on 31 July 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

object named as

Jinghui Luo

4

0 references

Christian R Kowol

object named as

Christian R Kowol

2

0 references

object named as

Eva A Enyedy

6

0 references

Astrid Gräslund

8

object named as

Astrid Gräslund

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

author name string

Ana Popović-Bijelić

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Maria E S Lind

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Fahmi Himo

5

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Vladimir B Arion

7

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

publication date

31 July 2011

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Journal of Inorganic Biochemistry

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

105

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

1422-1431

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Interaction of Triapine and related thiosemicarbazones with iron(III)/(II) and gallium(III): a comparative solution equilibrium study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

A phase II trial of triapine (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

A semiempirical free energy force field with charge-based desolvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

12 September 2017

Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

Fluorescence properties and cellular distribution of the investigational anticancer drug triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) and its zinc(II) complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

Reduction of Ribonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

Initial reaction of 3-ethyoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) copper(II) with Ehrlich ascites tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

14 September 2017

The iron-chelating drug triapine causes pronounced mitochondrial thiol redox stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

17 June 2018

Glutathione redox potential in response to differentiation and enzyme inducers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

17 June 2018

Increased ferritin gene expression is associated with increased ribonucleotide reductase gene expression and the establishment of hydroxyurea resistance in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

17 June 2018

Purification and characterization of recombinant mouse and herpes simplex virus ribonucleotide reductase R2 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

17 June 2018

Reduced forms of the iron-containing small subunit of ribonucleotide reductase from Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

17 June 2018

Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

21 August 2018

Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

21 August 2018

Biological activity of complexes derived from pyridine-2-carbaldehyde thiosemicarbazone. Structure of.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

21 August 2018

Coordination of heavy metals by dithiothreitol, a commonly used thiol group protectant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

21 August 2018

Characterization of the free radical of mammalian ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374975

21 August 2018

Studies of the reaction of 2-formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the biochemical mechanism of action of alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of 3-AP Triapine in patients with recurrent or metastatic head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of mammalian ribonucleotide reductase by the iron chelate of 1-formylisoquinoline thiosemicarbazone. Destruction of the tyrosine free radical of the enzyme in an oxygen-requiring reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltammetric evaluation of the effective acidities (pKa') for Broensted acids in aprotic solvents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction and loss of the iron center in the reaction of the small subunit of mouse ribonucleotide reductase with hydroxyurea

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ribonucleotide reductase in inhibition of mammalian cell growth by potent iron chelators

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of Triapine in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21955844

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JINORGBIO.2011.07.003

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

ResearchGate publication ID

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