(Q36114536)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Vinay Bulusu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Jurre J Kamphorst

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Francesca Schiavi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Karen Blyth

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Eyal Gottlieb

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Simone Cardaci

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Liang Zheng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Gillian MacKay

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Niels J F van den Broek

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Elaine D MacKenzie

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Colin Nixon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

David Stevenson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Alexei Vazquez

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Stewart Fleming

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Gabriela Kalna

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Douglas Strathdee

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

24 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

1317-1326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

22 February 2020

0 references

0 references

0 references

1 reference

22 June 2022

https://europepmc.org/article/PMC/4591470

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Defects in mitochondrial metabolism and cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Predicting selective drug targets in cancer through metabolic networks.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Inborn and acquired metabolic defects in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

SDHA is a tumor suppressor gene causing paraganglioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

The Warburg effect is genetically determined in inherited pheochromocytomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Germline SDHB mutations and familial renal cell carcinoma.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Structure, function and regulation of pyruvate carboxylase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

SDH mutations establish a hypermethylator phenotype in paraganglioma.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Renal carcinoma with giant mitochondria associated with germ-line mutation and somatic loss of the succinate dehydrogenase B gene

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591470

Calorie restriction and cancer prevention: a mechanistic perspective

23 September 2018

1 reference

Predicting selective drug targets in cancer through metabolic networks

21 January 2018

1 reference

A highly efficient recombineering-based method for generating conditional knockout mutations

21 January 2018

1 reference

Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals.

21 January 2018

1 reference

A transgenic mouse strain expressing four drug-selectable marker genes

21 January 2018

1 reference

Immortalized mouse epithelial cell models to study the role of apoptosis in cancer

21 January 2018

1 reference

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells.

21 January 2018

1 reference

Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells.

21 January 2018

1 reference

Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

21 January 2018

1 reference

Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate.

21 January 2018

1 reference

Analytical platform for metabolome analysis of microbial cells using methyl chloroformate derivatization followed by gas chromatography-mass spectrometry.

21 January 2018

1 reference

What is principal component analysis?

21 January 2018

1 reference

Renal Tumors and Hereditary Pheochromocytoma-Paraganglioma Syndrome Type 4

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26302408

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Null and conditionalsemaphorin 3B alleles using a flexiblepuro?tk loxP/FRT vector

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB3233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26302408%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26302408

1 reference