(Q36115910)

12 August 2017

1 reference

title

Clinical pharmacokinetics of calcium antagonists. An update (English)

1 reference

12 August 2017

1 reference

Kelly JG

1

1 reference

PubMed ID

1587055

12 August 2017

O'Malley K

series ordinal

2

1 reference

12 August 2017

1 June 1992

1 reference

Clinical Pharmacokinetics

12 August 2017

1 reference

12 August 2017

22

1 reference

12 August 2017

6

1 reference

12 August 2017

416-433

1 reference

https://scigraph.springernature.com/pub.10.2165/00003088-199222060-00002

12 August 2017

0 references

cites work

The pharmacokinetics of amlodipine in healthy volunteers after single intravenous and oral doses and after 14 repeated oral doses given once daily

1 reference

12 December 2020

Plasma protein binding of nilvadipine, a new dihydropyridine calcium antagonist, in man and dog

1 reference

12 December 2020

Pharmacokinetics of nifedipine slow release tablet in Mexican subjects: further evidence for an oxidation polymorphism

1 reference

12 December 2020

The effect of dihydropyridine calcium antagonists in hypertensive patients with impaired renal function

1 reference

12 December 2020

Pharmacokinetic studies of nifedipine tablet. Correlation with antihypertensive effects

1 reference

12 December 2020

Study of the influence of nifedipine on the pharmacokinetics and pharmacodynamics of propranolol, metoprolol and atenolol

1 reference

12 December 2020

Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

1 reference

12 December 2020

Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity

1 reference

12 December 2020

Nisoldipine: kinetics and effects on blood pressure and heart rate in patients with liver cirrhosis after intravenous and oral administration

1 reference

12 December 2020

Influence of nicardipine on the pharmacokinetics and pharmacodynamics of propranolol in healthy volunteers

1 reference

12 December 2020

High-performance liquid chromatography of nifedipine, its metabolites and photochemical degradation products

1 reference

12 December 2020

Influence of nisoldipine on haemodynamic effects and plasma levels of digoxin

1 reference

12 December 2020

Clinical pharmacokinetics of verapamil, nifedipine and diltiazem

1 reference

12 December 2020

Pharmacokinetics, bioavailability, metabolism and acute and chronic antihypertensive effects of nitrendipine in patients with chronic renal failure and moderate to severe hypertension.

1 reference

12 December 2020

Acute antiischaemic properties of high dosages of intravenous diltiazem in humans in relation to its coronary and systemic haemodynamic effects.

1 reference

12 December 2020

Nitrendipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of hypertension

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of two formulations of verapamil

1 reference

12 December 2020

Diltiazem and desacetyldiltiazem analysis in human plasma using high-performance liquid chromatography: improved sensitivity without derivation

1 reference

12 December 2020

Interaction of H2-receptor antagonists with drug-metabolizing enzymes

1 reference

12 December 2020

Nimodipine disposition and haemodynamic effects in patients with cirrhosis and age-matched controls

1 reference

12 December 2020

Gas chromatographic determination of nisoldipine and one of its metabolites in plasma

1 reference

12 December 2020

Pharmacokinetics and hemodynamic effects of nisoldipine and its interaction with cimetidine

1 reference

12 December 2020

Felodipine kinetics in healthy men.

1 reference

12 December 2020

Nifedipine: kinetics and dynamics in healthy subjects

1 reference

12 December 2020

1 reference

12 December 2020

Rapid high-performance liquid chromatographic method for the measurement of verapamil and norverapamil in blood plasma or serum

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of nitrendipine in healthy subjects and patients with kidney and liver disease

1 reference

12 December 2020

Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition

1 reference

12 December 2020

Pharmacokinetics of calcium antagonists

1 reference

12 December 2020

Pharmacokinetics of amlodipine in renal impairment

1 reference

12 December 2020

Determination of nifedipine in human plasma by capillary gas chromatography with nitrogen detection

1 reference

12 December 2020

Pharmacokinetics of felodipine in patients with liver disease

1 reference

12 December 2020

Verapamil kinetics in normal subjects and patients with coronary artery spasm

1 reference

12 December 2020

Pharmacokinetics of the enantiomers of felodipine in the dog after oral and intravenous administration of a pseudoracemic mixture

1 reference

12 December 2020

Pharmacokinetics of felodipine after intravenous and chronic oral administration in patients with congestive heart failure

1 reference

12 December 2020

Elimination and haemodynamic effects of nitrendipine in patients with chronic renal failure

1 reference

12 December 2020

Plasma protein binding and erythrocyte partitioning of nicardipine in vitro

1 reference

12 December 2020

Nimodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in cerebrovascular disease

1 reference

12 December 2020

Plasma Concentration vs. Effect Relationship for Felodipine

1 reference

12 December 2020

Haemodialysis does not affect the pharmacokinetics of nifedipine

1 reference

12 December 2020

Determination of nimodipine by gas chromatography using electron-capture detection; external factors influencing nimodipine concentrations during intravenous administration

1 reference

12 December 2020

Pharmacokinetics of nifedipine

1 reference

12 December 2020

Pharmacokinetics of verapamil in patients with renal failure.

1 reference

12 December 2020

Diltiazem. A reappraisal of its pharmacological properties and therapeutic use.

1 reference

12 December 2020

Lack of a pharmacokinetic interaction between nifedipine and the beta-adrenoceptor blockers metoprolol and atenolol

1 reference

12 December 2020

Rapid GC method for quantitation of nifedipine in serum using electron capture detection

1 reference

12 December 2020

Pharmacokinetic Properties and Antihypertensive Efficacy of Once-Daily Diltiazem

1 reference

12 December 2020

Inhibitory effect of uraemia on the hepatic clearance and metabolism of nicardipine

1 reference

12 December 2020

Determination of (+)- and (-)-nilvadipine in human plasma using chiral stationary-phase liquid chromatography and gas chromatography-mass spectrometry, and a preliminary pharmacokinetic study in humans

1 reference

12 December 2020

Pharmacokinetics of (+)-, (-)- and (+/-)-verapamil after intravenous administration

1 reference

12 December 2020

Pharmacokinetic interactions between felodipine and metoprolol

1 reference

12 December 2020

Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients. Altered electrocardiographic and hypotensive responses

1 reference

12 December 2020

Acute and long-term hypotensive effects and plasma concentrations of nifedipine in patients with essential hypertension

1 reference

12 December 2020

A population study of the pharmacokinetics of felodipine

1 reference

12 December 2020

Effects of (-), (+/- ), and (+) verapamil on coronary occlusion-induced mortality and infarct size.

1 reference

12 December 2020

A comparison of the pharmacokinetics of nisoldipine in elderly and young subjects

1 reference

12 December 2020

Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension

1 reference

12 December 2020

Nicardipine does not influence the pharmacokinetics and pharmacodynamics of atenolol

1 reference

12 December 2020

Circadian variation in the pharmacokinetics of verapamil

1 reference

12 December 2020

Pharmacokinetics of diltiazem in severe renal failure

1 reference

12 December 2020

Clinical pharmacokinetics of felodipine. A summary

1 reference

12 December 2020

Effect of the calcium channel blocker diltiazem on cyclosporine A blood levels and dose requirements

1 reference

12 December 2020

Clearance-based oral drug interaction between verapamil and metoprolol and comparison with atenolol

1 reference

12 December 2020

The effects of renal function on the disposition of isradipine

1 reference

12 December 2020

Acute and chronic effects of nifedipine in arterial hypertension

1 reference

12 December 2020

Importance of oral dosing rate on the hemodynamic and pharmacokinetic profile on nilvadipine

1 reference

12 December 2020

Pharmacokinetics of oral diltiazem and five of its metabolites in patients with chronic renal failure

1 reference

12 December 2020

Clinical pharmacokinetics of nimodipine in normal and impaired renal function

1 reference

12 December 2020

Absorption, distribution and elimination of felodipine in man

1 reference

12 December 2020

Calcium antagonists in the treatment of hypertension and angina pectoris in the elderly

1 reference

12 December 2020

High-performance liquid chromatographic analysis of verapamil. II. Simultaneous quantitation of verapamil and its active metabolite, norverapamil

1 reference

12 December 2020

Serum concentrations and effects of (+/-)-nicardipine compared with nifedipine in a population of healthy subjects

1 reference

12 December 2020

Pharmacokinetics of felodipine and effect on digoxin plasma levels in patients with heart failure

1 reference

12 December 2020

The metabolism and pharmacokinetics of nicardipine hydrochloride in man.

1 reference

12 December 2020

Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of verapamil in combination with atenolol, metoprolol and propranolol.

1 reference

12 December 2020

Variability in the pharmacokinetics of nisoldipine as caused by differences in liver blood flow response

1 reference

12 December 2020

Effects of impaired renal function on the pharmacokinetics of felodipine

1 reference

12 December 2020

Pharmacokinetics of nisoldipine in renal dysfunction

1 reference

12 December 2020

Total and free steady-state plasma levels and pharmacokinetics of nifedipine in patients with terminal renal failure

1 reference

12 December 2020

Commentary: a physiological approach to hepatic drug clearance

1 reference

12 December 2020

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview

1 reference

12 December 2020

Drug interactions with nitrendipine

1 reference

12 December 2020

Chronopharmacological study of nitrendipine in healthy subjects

1 reference

12 December 2020

The long-term effect of verapamil on plasma digoxin concentration and renal digoxin clearance in healthy subjects

1 reference

12 December 2020

Plasma concentration-response relationships for some cardiovascular effects of dihydropyridines in healthy subjects.

1 reference

12 December 2020

The effect of verapamil on antipyrine pharmacokinetics and metabolism in man.

1 reference

12 December 2020

Drug interactions with the calcium-entry blockers

1 reference

12 December 2020

Nifedipine kinetics and bioavailability after single intravenous and oral doses in normal subjects

1 reference

12 December 2020

Simple sensitive and specific gas chromatographic method for the quantification of diltiazem human body fluids

1 reference

12 December 2020

Verapamil disposition--effects of sulphinpyrazone and cimetidine

1 reference

12 December 2020

Steady-state pharmacokinetics of nitrendipine in hepatic insufficiency

1 reference

12 December 2020

Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis

1 reference

12 December 2020

Pharmacokinetics of diltiazem in patients with liver cirrhosis

1 reference

12 December 2020

Pharmacokinetics, pharmacodynamics, and minimum effective clinical dose of intravenous nicardipine

1 reference

12 December 2020

The comparative effects of verapamil and a new dihydropyridine calcium channel blocker on digoxin pharmacokinetics

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic interactions between nisoldipine and propranolol.

1 reference

12 December 2020

Application of stable isotope methodology to study the pharmacokinetics, bioavailability and metabolism of nitrendipine after i.v. and p.o. administration

1 reference

12 December 2020

The influence of verapamil on serum digoxin concentration

1 reference

12 December 2020

Intragastric behavior and absorption kinetics of a normal and "floating" modified-release capsule of isradipine under fasted and fed conditions.

1 reference

12 December 2020

Improved gas chromatographic determination of diltiazem and deacetyldiltiazem in human plasma

1 reference

12 December 2020

Analysis of amlodipine in human plasma by gas chromatography

1 reference

12 December 2020

Use of calcium entry blockers in elderly patients. Special considerations

1 reference

12 December 2020

Pharmacokinetics of diltiazem and its metabolites after repeated multiple-dose treatments in healthy volunteers

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic studies of felodipine in healthy subjects after various single, oral and intravenous doses.

1 reference

12 December 2020

Felodipine ER formulation in the treatment of mild hypertension: efficacy and tolerability vs placebo

1 reference

12 December 2020

Pharmacokinetics of nitrendipine in terminal renal failure

1 reference

12 December 2020

The antihypertensive efficacy of verapamil in the elderly evaluated by ambulatory blood pressure measurement.

1 reference

12 December 2020

Plasma nifedipine levels and fall in blood pressure in a 53 year old woman

1 reference

12 December 2020

Reduction of bioavailability of verapamil by rifampin

1 reference

12 December 2020

The effects of age and race on nitrendipine pharmacokinetics and pharmacodynamics.

1 reference

12 December 2020

A high-performance liquid chromatographic method for the simultaneous determination of nicardipine and its pyridine metabolite II in plasma

1 reference

12 December 2020

Pharmacodynamic aspects of intravenous diltiazem administration

1 reference

12 December 2020

Disposition of nitrendipine in patients with chronic liver diseases

1 reference

12 December 2020

Pharmacokinetics and hemodynamic effects of long-term nisoldipine treatment in hypertensive patients

1 reference

12 December 2020

Application of pharmacokinetic-pharmacodynamic modelling for the comparison of quinazoline alpha-adrenoceptor agonists in normotensive volunteers.

1 reference

12 December 2020

Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders

1 reference

12 December 2020

Influence of renal function on the pharmacokinetics and cardiovascular effects of nisoldipine after single and multiple dosing

1 reference

12 December 2020

Ranitidine and cimetidine; drug interactions with single dose and steady-state nifedipine administration

1 reference

12 December 2020

Pharmacokinetics of nitrendipine in patients with renal failure: comparison to normal subjects

1 reference

12 December 2020

Diltiazem. A review of its pharmacological properties and therapeutic efficacy

1 reference

12 December 2020

Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function

1 reference

12 December 2020

The effect of hepatic cirrhosis on the pharmacokinetics and blood pressure response to nicardipine

1 reference

12 December 2020

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

1 reference

12 December 2020

Nifedipine: influence of renal function on pharmacokinetic/hemodynamic relationship

1 reference

12 December 2020

Sustained-release diltiazem compared with atenolol monotherapy for mild to moderate systemic hypertension

1 reference

12 December 2020

The binding of drugs to plasma proteins from patients with poor renal function

1 reference

12 December 2020

Determination of felodipine in plasma by capillary gas chromatography with electron capture detection

1 reference

12 December 2020

Ethnic differences in the pharmacokinetics of oral nifedipine

1 reference

12 December 2020

A comparison of the disposition of single oral doses of amlodipine in young and elderly subjects

1 reference

12 December 2020

Differences in oral verapamil absorption as a function of time of day.

1 reference

12 December 2020

Pharmacokinetics of nilvadipine in healthy volunteers.

1 reference

12 December 2020

Changes in antipyrine and indocyanine green kinetics during nifedipine, verapamil, and diltiazem therapy

1 reference

12 December 2020

Determination of a new cerebral vasodilator 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ethyl ester 5-methyl ester hydrochloride (YC-93) in plasma by electron capture gas chromatography

1 reference

12 December 2020

Bioavailability and elimination of nitrendipine in liver disease

1 reference

12 December 2020

Effect of nicardipine in elderly hypertensive patients

1 reference

12 December 2020

Plasma concentrations of nifedipine in patients with renal failure

1 reference

12 December 2020

Overview on pharmacokinetics of nimodipine in healthy volunteers and in patients with subarachnoid hemorrhage.

1 reference

12 December 2020

The effect of ranitidine and cimetidine on single-dose diltiazem pharmacokinetics

1 reference

12 December 2020

Aging alters verapamil elimination and dynamics: single dose and steady-state responses.

1 reference

12 December 2020

Pharmacokinetics of calcium antagonists under development

1 reference

12 December 2020

10.2165/00003088-199222060-00002

Identifiers

DOI

1 reference

PubMed ID

1587055

Dimensions Publication ID

12 August 2017

0 references

1 reference

PubMed ID

1587055