(Q36117745)

12 August 2017

SecY alterations that impair membrane protein folding and generate a membrane stress (English)

1 reference

12 August 2017

0 references

1 reference

4

H Ronald Kaback

1 reference

12 August 2017

Nobuyuki Shimohata

1

1 reference

12 August 2017

Shushi Nagamori

series ordinal

2

1 reference

12 August 2017

Yoshinori Akiyama

series ordinal

3

1 reference

12 August 2017

Koreaki Ito

series ordinal

5

1 reference

12 August 2017

language of work or name

English

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publication date

22 January 2007

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12 August 2017

11

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

176

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12 August 2017

3

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12 August 2017

307-317

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Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Manipulating phospholipids for crystallization of a membrane transport protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Structure of the E. coli protein-conducting channel bound to a translating ribosome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Peculiar properties of DsbA in its export across the Escherichia coli cytoplasmic membrane

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Recognition of transmembrane helices by the endoplasmic reticulum translocon.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Proteolysis as a regulatory mechanism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Quality control in the bacterial periplasm

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Sec-translocase mediated membrane protein biogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

SRP-mediated protein targeting: structure and function revisited

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Fine-tuning of the Escherichia coli sigmaE envelope stress response relies on multiple mechanisms to inhibit signal-independent proteolysis of the transmembrane anti-sigma factor, RseA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

RseP (YaeL), an Escherichia coli RIP protease, cleaves transmembrane sequences

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Membrane-protein integration and the role of the translocation channel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

YidC family members are involved in the membrane insertion, lateral integration, folding, and assembly of membrane proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Mutational analysis of transmembrane regions 3 and 4 of SecY, a central component of protein translocase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Regulation of the Escherichia coli sigma-dependent envelope stress response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Role of YidC in folding of polytopic membrane proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Sec61p contributes to signal sequence orientation according to the positive-inside rule

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

X-ray structure of a protein-conducting channel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Secretion defects that activate the phage shock response of Escherichia coli.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

The DsbA signal sequence directs efficient, cotranslational export of passenger proteins to the Escherichia coli periplasm via the signal recognition particle pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Structure and mechanism of the lactose permease of Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Molecular mechanism of signal sequence orientation in the endoplasmic reticulum

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Biochemical characterization of a mutationally altered protein translocase: proton motive force stimulation of the initiation phase of translocation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

The Sec protein-translocation pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

The targeting pathway of Escherichia coli presecretory and integral membrane proteins is specified by the hydrophobicity of the targeting signal

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Physiological basis for conservation of the signal recognition particle targeting pathway in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

A mutation in secY that causes enhanced SecA insertion and impaired late functions in protein translocation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

The Cpx two-component signal transduction pathway is activated in Escherichia coli mutant strains lacking phosphatidylethanolamine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Identification of the epitope for monoclonal antibody 4B1 which uncouples lactose and proton translocation in the lactose permease of Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Determinants of the quantity of the stable SecY complex in the Escherichia coli cell

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Characterization of an amber mutation in the structural gene for ribosomal protein L15, which impairs the expression of the protein export gene, secY, in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

secD, a new gene involved in protein export in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Characterization and functional reconstitution of a soluble form of the hydrophobic membrane protein lac permease from Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Characterization of cold-sensitive secY mutants of Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

SecY, a multispanning integral membrane protein, contains a potential leader peptidase cleavage site

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Dissecting the translocase and integrase functions of the Escherichia coli SecYEG translocon

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Phospholipid-assisted protein folding: phosphatidylethanolamine is required at a late step of the conformational maturation of the polytopic membrane protein lactose permease

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Genetic analysis of SecY: additional export-defective mutations and factors affecting their phenotypes.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

A low-copy-number vector utilizing beta-galactosidase for the analysis of gene control elements.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Export of Escherichia coli alkaline phosphatase attached to an integral membrane protein, SecY.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

SecY protein, a membrane-embedded secretion factor of E. coli, is cleaved by the ompT protease in vitro

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

In vivoanalysis of integration of membrane proteins inEscherichia coli

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2063957

Translocation, folding, and stability of the HflKC complex with signal anchor topogenic sequences

2 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

Membrane topology inversion of SecG detected by labeling with a membrane-impermeable sulfhydryl reagent that causes a close association of SecG with SecA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

In vitro synthesis of lactose permease to probe the mechanism of membrane insertion and folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

SecDFyajC forms a heterotetrameric complex with YidC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

Proteolytic activity of HtpX, a membrane-bound and stress-controlled protease from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

The Cpx stress response system of Escherichia coli senses plasma membrane proteins and controls HtpX, a membrane protease with a cytosolic active site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

Product of a new gene, syd, functionally interacts with SecY when overproduced in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

The last two cytoplasmic loops in the lactose permease of Escherichia coli comprise a discontinuous epitope for a monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

Different regions of the nonconserved large periplasmic domain of Escherichia coli YidC are involved in the SecF interaction and membrane insertase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

The Protein Translocation Apparatus Contributes to Determining the Topology of an Integral Membrane Protein inEscherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200611121

A mutation in the Escherichia coli secY gene that produces distinct effects on inner membrane protein insertion and protein export

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17242069

12 December 2020

inferred from PubMed ID database lookup

YidC mediates membrane protein insertion in bacteria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17242069

12 December 2020

inferred from PubMed ID database lookup

The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17242069

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200611121

1 reference

12 August 2017

1 reference

12 August 2017

1 reference