(Q36125476)

English

Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Evaluation of the QT effect of a combination of piperaquine and a novel anti-malarial drug candidate OZ439, for the treatment of uncomplicated malaria (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

0 references

author name string

Borje Darpo

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Georg Ferber

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Peter Siegl

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Bart Laurijssens

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Fiona Macintyre

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Stephen Toovey

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Stephan Duparc

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

13 May 2015

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

80

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

706-715

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over prolonged corrected QT interval

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

The IQ-CSRC prospective clinical Phase 1 study: "Can early QT assessment using exposure response analysis replace the thorough QT study?".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Early QT assessment--how can our confidence in the data be improved?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malariaedit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Malarial cases presenting to a European urban Emergency Department

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

In vitro cardiovascular effects of dihydroartemisin-piperaquine combination compared with other antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Population pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Considerations for clinical trial design and data analyses of thorough QT studies using drug-drug interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Cardiotoxicity of antimalarial drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 October 2017

Blockade of currents by the antimalarial drug chloroquine in feline ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

2 July 2018

Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

23 September 2018

Artemisinin resistance is a clear and present danger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4594707

23 September 2018

Torsades de pointes associated with nonantiarrhythmic drugs and observations on gender and QTc

1 reference

https://pubmed.ncbi.nlm.nih.gov/25966781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictive factors of ventricular fibrillation triggered by pause-dependent torsades de pointes associated with acquired long QT interval: role of QT dispersion and left ventricular function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25966781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of QTc effects in small studies--implications for replacing the thorough QT study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25966781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BCP.12680

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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