(Q36132575)

12 August 2017

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title

Combined lipoxygenase/cyclo-oxygenase inhibition in the elderly: the example of licofelone (English)

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12 August 2017

Giuseppe Derosa

2

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author name string

Arrigo F G Cicero

series ordinal

1

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12 August 2017

Antonio Gaddi

series ordinal

3

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12 August 2017

publication date

1 January 2005

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12 August 2017

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12 August 2017

volume

22

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12 August 2017

issue

5

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12 August 2017

page(s)

393-403

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https://scigraph.springernature.com/pub.10.2165/00002512-200522050-00004

12 August 2017

exact match

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cites work

Renal tolerance of selective inhibitors of cyclooxygenase type 2

1 reference

12 December 2020

Cyclooxygenase 2-implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives

1 reference

12 December 2020

Pros and cons of selective inhibition of cyclooxygenase-2 versus dual lipoxygenase/cyclooxygenase inhibition: is two better than one?

1 reference

12 December 2020

Studies on the in vitro and in vivo genotoxicity of [2,2-dimethyl-6- (4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid

1 reference

12 December 2020

The effects of ML 3000 on antigen-induced responses in sheep

1 reference

12 December 2020

In vivo protective effects of prophylactic treatment with tiaprofenic acid or intraarticular corticosteroids on osteoarthritic lesions in the experimental dog model

1 reference

12 December 2020

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study

1 reference

12 December 2020

NSAIDS and selective COX-2 inhibitors: competition between gastroprotection and cardioprotection

1 reference

12 December 2020

A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure

1 reference

12 December 2020

In vivo dual inhibition of cyclooxygenase and lipoxygenase by ML-3000 reduces the progression of experimental osteoarthritis: suppression of collagenase 1 and interleukin-1beta synthesis

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12 December 2020

Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition

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12 December 2020

Relative contribution of acetylated cyclooxygenase (COX)‐2 and 5‐lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin

1 reference

12 December 2020

Risk of cardiovascular events and rofecoxib: cumulative meta-analysis

1 reference

12 December 2020

NSAID induced gastrointestinal complications: the ARAMIS perspective--1997. Arthritis, Rheumatism, and Aging Medical Information System.

1 reference

12 December 2020

Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib

1 reference

12 December 2020

General pharmacology of [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3- dihydro-1H-pyrrolizine-5-yl]-acetic acid in experimental animals.

1 reference

12 December 2020

Renal effects of cyclooxygenase-2 selective inhibitors

1 reference

12 December 2020

Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving a low-salt diet. A randomized, controlled trial.

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12 December 2020

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12 December 2020

Selective COX-2 Inhibitors and Dual Acting Anti-inflammatory Drugs: Critical Remarks

1 reference

12 December 2020

Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey

1 reference

12 December 2020

What are the goals and principles of management in the early treatment of rheumatoid arthritis?

1 reference

12 December 2020

Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults

1 reference

12 December 2020

Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation

1 reference

12 December 2020

In vivo effect of aspirin on canine osteoarthritic cartilage

1 reference

12 December 2020

The mechanism of action of the new antiinflammatory compound ML3000: inhibition of 5-LOX and COX-1/2.

1 reference

12 December 2020

New trends in dual 5-LOX/COX inhibition

1 reference

12 December 2020

Leukotrienes and lipoxins: lipoxygenase-derived modulators of leukocyte recruitment and vascular tone in glomerulonephritis

1 reference

12 December 2020

Carprofen simultaneously reduces progression of morphological changes in cartilage and subchondral bone in experimental dog osteoarthritis

1 reference

12 December 2020

Acute and chronic anti-inflammatory properties of [2,2-dimethyl-6-(4- chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid

1 reference

12 December 2020

ML 3000 reduces gastric prostaglandin synthesis without causing mucosal injury

1 reference

12 December 2020

Gastroprotective therapy and risk of gastrointestinal ulcers: risk reduction by COX-2 therapy.

1 reference

12 December 2020

Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?

1 reference

12 December 2020

Clinical perspectives of anti-inflammatory therapy in the elderly: the lipoxigenase (LOX)/cycloxigenase (COX) inhibition concept

1 reference

12 December 2020

Blood pressure, stroke, and coronary heart disease

1 reference

12 December 2020

Adverse drug events in high risk older outpatients

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs and acute renal failure in the elderly. A risk-benefit assessment

1 reference

12 December 2020

The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial.

1 reference

12 December 2020

1 reference

12 December 2020

Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response

1 reference

12 December 2020

Differential effects of aspirin and non-aspirin nonsteroidal antiinflammatory drugs in the primary prevention of myocardial infarction in postmenopausal women

1 reference

12 December 2020

Polypharmacy, adverse drug-related events, and potential adverse drug interactions in elderly patients presenting to an emergency department

1 reference

12 December 2020

1 reference

12 December 2020

Rofecoxib: clinical pharmacology and clinical experience

1 reference

12 December 2020

Pain and quality of life among older people with rheumatoid arthritis and/or osteoarthritis: a literature review

1 reference

12 December 2020

COX-2 inhibitors and the kidney

1 reference

12 December 2020

Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors

1 reference

12 December 2020

Dual inhibition of 5-lipoxygenase and cyclooxygenases 1 and 2 by ML3000 reduces joint destruction in adjuvant arthritis.

1 reference

12 December 2020

Gastrointestinal tolerability of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib compared with nonselective COX-1 and COX-2 inhibitors in osteoarthritis.

1 reference

12 December 2020

Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side

1 reference

12 December 2020

Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs

1 reference

12 December 2020

Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs.

1 reference

12 December 2020

Non-steroidal anti-inflammatory drugs and hypertension in the elderly: a community-based cross-sectional study

1 reference

12 December 2020

The in vivo effects of intraarticular corticosteroid injections on cartilage lesions, stromelysin, interleukin-1, and oncogene protein synthesis in experimental osteoarthritis

1 reference

12 December 2020

Underestimation of Risk Associations Due to Regression Dilution in Long-term Follow-up of Prospective Studies

1 reference

12 December 2020

Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept.

1 reference

12 December 2020

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

1 reference

12 December 2020

Licofelone, a dual lipoxygenase-cyclooxygenase inhibitor, downregulates polymorphonuclear leukocyte and platelet function

1 reference

12 December 2020

Pharmacological therapy of osteoarthritis

1 reference

12 December 2020

Pharmacological profile of a new pyrrolizine derivative inhibiting the enzymes cyclo-oxygenase and 5-lipoxygenase

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12 December 2020

Raising the safety bar--the FDA's coxib meeting

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12 December 2020

10.2165/00002512-200522050-00004

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

1019014442

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