(Q36135032)

12 August 2017

DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumour cells (English)

1 reference

12 August 2017

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5

Patterson LH

1 reference

12 August 2017

2

McKeown SR

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12 August 2017

Hejmadi MV

1

1 reference

12 August 2017

Friery OP

series ordinal

3

1 reference

12 August 2017

McIntyre IA

series ordinal

4

1 reference

12 August 2017

Hirst DG

series ordinal

6

1 reference

12 August 2017

language of work or name

English

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publication date

1 February 1996

1 reference

British Journal of Cancer

12 August 2017

1 reference

12 August 2017

73

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12 August 2017

4

1 reference

12 August 2017

499-505

1 reference

https://scigraph.springernature.com/pub.10.1038/bjc.1996.87

12 August 2017

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cites work

The experimental development of bioreductive drugs and their role in cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

EO9: relationship between DT-diaphorase levels and response in vitro and in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

The single cell gel electrophoresis assay (comet assay): a European review

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

A simple technique for quantitation of low levels of DNA damage in individual cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Molecular assays of radiation-induced DNA damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Definitive evidence for hypoxic cells influencing cure in cancer therapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

The dynamics of tumor cords in an irradiated mouse mammary carcinoma with a large hypoxic cell component.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Hypobaric hypoxia: A method for testing bioreductive drugs in vivo

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074454

Growth fraction measured using the comet assay

2 July 2018

1 reference

12 December 2020

Oxygen tension distributions are sufficient to explain the local response of human breast tumors treated with radiation alone

1 reference

12 December 2020

Radiation-induced reoxygenation in the SCCVII murine tumour: evidence for a decrease in oxygen consumption and an increase in tumour perfusion

1 reference

12 December 2020

Aliphatic amine N-oxides of DNA binding agents as bioreductive drugs

1 reference

12 December 2020

Variability in the expression of xenobiotic-metabolizing enzymes during the growth cycle of rat hepatoma cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1996.87

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

8595165

1 reference