(Q36135586)

12 August 2017

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title

The implications of P-glycoprotein in HIV: friend or foe? (English)

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12 August 2017

Andrew Owen

1

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author name string

Becky Chandler

series ordinal

2

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12 August 2017

David J Back

series ordinal

3

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12 August 2017

language of work or name

1 reference

1 June 2005

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Fundamental and Clinical Pharmacology

12 August 2017

published in

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12 August 2017

volume

19

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12 August 2017

issue

3

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12 August 2017

page(s)

283-296

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The mechanisms that control intracellular penetration of the HIV protease inhibitors

12 August 2017

cites work

1 reference

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Multidrug resistance protein 1-mediated transport of saquinavir by microglia

21 January 2018

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Differences in the intracellular accumulation of HIV protease inhibitors in vitro and the effect of active transport

21 January 2018

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P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

21 January 2018

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Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).

21 January 2018

1 reference

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Expression of P-glycoprotein, multidrug-resistance proteins 1 and 2 in CEM, CEM(VBL), CEM(E1000), MDCKII(MRP1) and MDCKII(MRP2) cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs

21 January 2018

1 reference

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Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4.

21 January 2018

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HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

21 January 2018

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MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

21 January 2018

1 reference

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Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus

21 January 2018

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A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

21 January 2018

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P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

21 January 2018

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Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture

21 January 2018

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

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Basal expression of the multidrug resistance gene 1 (MDR-1) is associated with the TT genotype at the polymorphic site C3435T in mammary and ovarian carcinoma cell lines

21 January 2018

1 reference

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Naturally occurring mutations and functional polymorphisms in multidrug resistance 1 gene: correlation with microsatellite instability and lymphoid infiltration in colorectal cancers

21 January 2018

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Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

21 January 2018

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Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease

21 January 2018

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

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Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

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Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein

21 January 2018

1 reference

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Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

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Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture.

21 January 2018

1 reference

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Saquinavir induces stable and functional expression of the multidrug transporter P-glycoprotein in human CD4 T-lymphoblastoid CEMrev cells.

21 January 2018

1 reference

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Transcriptional regulation of ABC drug transporters

21 January 2018

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

21 January 2018

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Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.

21 January 2018

1 reference

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Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection

21 January 2018

1 reference

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MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Differential expression of human immunodeficiency virus coreceptors, by CEM, CEMVBL, and CEM E1000 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Caveolin-1 gene is coordinately regulated with the multidrug resistance 1 gene in normal and leukemic bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Caveolae: from cell biology to animal physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Exclusion of a Transmembrane-Type Peptide from Ordered-Lipid Domains (Rafts) Detected by Fluorescence Quenching: Extension of Quenching Analysis to Account for the Effects of Domain Size and Domain Boundaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

How proteins move lipids and lipids move proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Emerging themes in lipid rafts and caveolae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Polarity and lipid raft association of the components of the ciliary neurotrophic factor receptor complex in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Lipid rafts mediate the interaction between myelin-associated glycoprotein (MAG) on myelin and MAG-receptors on neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Overexpression of caveolin-1 increases plasma membrane fluidity and reduces P-glycoprotein function in Hs578T/Dox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Overexpression of caveolin-1 induces alteration of multidrug resistance in Hs578T breast adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Blockade of human immunodeficiency virus type 1 expression by caveolin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors in vivo correlates with HIV-1 disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Modulation of cellular cholesterol alters P-glycoprotein activity in multidrug-resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

The expression of P-glycoprotein and cellular kinases is modulated at the transcriptional level by infection and highly active antiretroviral therapy in a primate model of AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2005.00324.X

10.1111/J.1472-8206.2005.00324.X

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference