(Q36140753)

English

Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

James Greenaway

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jack Lawler

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Roger Moorehead

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Paul Bornstein

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jonathan Lamarre

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jim Petrik

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

publication date

1 March 2007

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

Journal of Cellular Physiology

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

210

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

807-818

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

VEGF induces proliferation, migration, and TGF-beta1 expression in mouse glomerular endothelial cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase

1 reference

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2 October 2017

Endogenous inhibitors of angiogenesis.

1 reference

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2 October 2017

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

1 reference

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2 October 2017

Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia

1 reference

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2 October 2017

Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Vascular endothelial growth factor: basic science and clinical progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells

1 reference

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2 October 2017

The anti-angiogenic basis of metronomic chemotherapy

1 reference

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2 October 2017

Angiogenic and antiangiogenic balance regulates concomitant antitumoral resistance

1 reference

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2 October 2017

Tumor progression: the effects of thrombospondin-1 and -2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondins 1 and 2 function as inhibitors of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Angiogenesis in the primate ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin-1, vascular endothelial growth factor expression and their relationship with p53 status in prostate cancer and benign prostatic hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Diverse roles for the LDL receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Divergent Pseudomonas exotoxin A sensitivity in normal and transformed liver cells is correlated with low-density lipoprotein receptor-related protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Role of rap in the biogenesis of lipoprotein receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Short-term administration of antivascular endothelial growth factor antibody in the late follicular phase delays follicular development in the rhesus monkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Ovulation as a tissue remodelling process. Proteolysis and cumulus expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Thrombospondins: structure and regulation of expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

The role of angiogenesis in tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 October 2017

Effects of angiogenic growth factor combinations on retinal endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 July 2018

Increased expression of low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor in human malignant astrocytomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 July 2018

Relationship between blood flow and steroidogenesis in the rabbit corpus luteum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 July 2018

Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

2 July 2018

Regulation of apoptosis in the atresia of dominant bovine follicles of the first follicular wave following ovulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

The vascular endothelial growth factor (VEGF)/VEGF receptor 2 pathway is critical for blood vessel survival in corpora lutea of pregnancy in the rodent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Thombospondin-1 disrupts estrogen-induced endothelial cell proliferation and migration and its expression is suppressed by estradiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Vascular endothelial growth factor and its receptor, Flk-1/KDR, are cytoprotective in the extravascular compartment of the ovarian follicle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Thrombospondin-1-deficient mice exhibit increased vascular density during retinal vascular development and are less sensitive to hyperoxia-mediated vessel obliteration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Expression and localization of thrombospondin-1 and -2 and their cell-surface receptor, CD36, during rat follicular development and formation of the corpus luteum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Prevention of thecal angiogenesis, antral follicular growth, and ovulation in the primate by treatment with vascular endothelial growth factor Trap R1R2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

Expression and localisation of vascular endothelial growth factor and basic fibroblast growth factor during the final growth of bovine ovarian follicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

23 September 2018

The thrombospondins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412056

21 October 2018

Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin and vascular endothelial growth factor are cyclically expressed in an inverse pattern during bovine ovarian follicle development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revisiting the ovarian volume as a diagnostic criterion for polycystic ovaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular Endothelial Growth Factor Production in Growing Pig Antral Follicles1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microvessel quantification in benign and malignant ovarian tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human breast tumors override the antiangiogenic effect of stromal thrombospondin-1 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Second and Fourth Cluster of Class A Cysteine-rich Repeats of the Low Density Lipoprotein Receptor-related Protein Share Ligand-binding Properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural organization of the receptor associated protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neovascularization of the corpus luteum of rats during the estrus cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative effects of VEGF-A and VEGF-C on endothelial cell proliferation, migration and PAF synthesis: Role of neuropilin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low Density Lipoprotein Receptor-related Protein/[IMAGE][IMAGE]-Macroglobulin Receptor Mediates the Cellular Internalization and Degradation of Thrombospondin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shift in the balance between circulating thrombospondin-1 and vascular endothelial growth factor in cancer patients: relationship to platelet alpha-granule content and primary activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted overexpression of the angiogenesis inhibitor thrombospondin-1 in the epidermis of transgenic mice prevents ultraviolet-B-induced angiogenesis and cutaneous photo-damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17154366

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JCP.20904

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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