(Q36143388)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

review article

1 reference

title

Foundation Review: Transgenic animals and their impact on the drug discovery industry (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

David A Dunn

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

David L Kooyman

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

publication date

1 June 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

757-767

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15922934%20AND%20SRC:MED&resulttype=core&format=json

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

12 January 2020

cites work

1 reference

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7 January 2021

Recovery and Culture of Tubal Mouse Ova

1 reference

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7 January 2021

STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. I. THE EFFECT OF OSMOLARITY AND HYDROGEN ION CONCENTRATION.

1 reference

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7 January 2021

STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. II. THE EFFECT OF ENERGY SOURCE.

1 reference

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7 January 2021

STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. 3. THE EFFECT OF FIXED-NITROGEN SOURCE

1 reference

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7 January 2021

Studies on the development of mouse embryos in vitro. IV. Interaction of energy sources

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7 January 2021

Microinjection of mouse eggs

1 reference

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7 January 2021

Genetic transformation of mouse embryos by microinjection of purified DNA

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7 January 2021

Somatic expression of herpes thymidine kinase in mice following injection of a fusion gene into eggs

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7 January 2021

Introduction of a rabbit beta-globin gene into the mouse germ line

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7 January 2021

Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal.

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7 January 2021

The human beta-globin gene and a functional viral thymidine kinase gene in developing mice.

1 reference

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7 January 2021

Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring

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7 January 2021

DNA Restriction Enzyme from E. coli

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7 January 2021

Cleavage of DNA by R 1 restriction endonuclease generates cohesive ends

1 reference

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7 January 2021

Recircularization and Autonomous Replication of a Sheared R-Factor DNA Segment in Escherichia coli Transformants

1 reference

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7 January 2021

Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage

1 reference

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7 January 2021

Construction of Biologically Functional Bacterial Plasmids In Vitro

1 reference

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7 January 2021

Efficient insertion of genes into the mouse germ line via retroviral vectors

1 reference

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7 January 2021

Altering the genome by homologous recombination

1 reference

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7 January 2021

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

1 reference

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7 January 2021

Full-term development after transplantation of parthenogenetic embryonic nuclei into fertilized mouse eggs

1 reference

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7 January 2021

Nuclear transplantation in the mouse embryo by microsurgery and cell fusion

1 reference

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7 January 2021

Viable offspring derived from fetal and adult mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Monoclonal mice generated by nuclear transfer from mature B and T donor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Germ cell transplantation in pigs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Aging of animals produced by somatic cell nuclear transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

A species of small antisense RNA in posttranscriptional gene silencing in plants

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Killing the messenger: short RNAs that silence gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Varying the Nucleic Acid Composition of siRNA Molecules Dramatically Varies the Duration and Degree of Gene Silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Small interfering RNA and gene silencing in transgenic mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

siRNA-directed inhibition of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Sperm cells as vectors for introducing foreign DNA into eggs: genetic transformation of mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

No simple solution for making transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Germline transmission of donor haplotype following spermatogonial transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Growth factors essential for self-renewal and expansion of mouse spermatogonial stem cells

1 reference

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7 January 2021

Production of homoplasmic xenomitochondrial mice

1 reference

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7 January 2021

Production of transmitochondrial mice.

1 reference

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7 January 2021

Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice

1 reference

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7 January 2021

Formation of beta-amyloid protein deposits in brains of transgenic mice

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7 January 2021

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

1 reference

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7 January 2021

Mouse models of obesity

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7 January 2021

Mouse models for the study of Crohn's disease

1 reference

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7 January 2021

Transgenic mouse models of dopamine deficiency

1 reference

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7 January 2021

Transgenic models of ovarian failure

1 reference

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7 January 2021

Modelling haematopoietic malignancies in the mouse and therapeutical implications

1 reference

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7 January 2021

The use of the uromodulin promoter to target production of recombinant proteins into urine of transgenic animals

1 reference

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7 January 2021

The bladder as a bioreactor: urothelium production and secretion of growth hormone into urine

1 reference

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7 January 2021

Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice

1 reference

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7 January 2021

Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody

1 reference

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7 January 2021

Transgenic mice expressing a chimaeric anti-E. coli immunoglobulin alpha heavy chain gene.

1 reference

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7 January 2021

Humanized IgG1 and IgG4 anti-CD4 monoclonal antibodies: effects on lymphocytes in the blood, lymph nodes, and renal allografts in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Production of fully human antibodies by transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Strategies for expressing human antibody repertoires in transgenic mice

1 reference

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7 January 2021

Cloned transchromosomic calves producing human immunoglobulin

1 reference

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7 January 2021

Transplantation of discordant xenografts: a review of progress

1 reference

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7 January 2021

Prolongation of cardiac xenograft survival by depletion of complement

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7 January 2021

The regulators of complement activation (RCA) gene cluster

1 reference

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7 January 2021

Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium

1 reference

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7 January 2021

Glaxo/MRS Young Investigator Prize. Xenotransplantation: immune barriers beyond hyperacute rejection

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7 January 2021

Immunology of xenotransplantation

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7 January 2021

Combined transgenic expression of alpha-galactosidase and alpha1,2-fucosyltransferase leads to optimal reduction in the major xenoepitope Galalpha(1,3)Gal

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

The role of natural anti-Gal alpha 1-3Gal antibodies in hyperacute rejection of pig-to-baboon cardiac xenotransplants

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7 January 2021

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

1 reference

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7 January 2021

Production of alpha 1,3-galactosyltransferase-knockout cloned pigs expressing human alpha 1,2-fucosylosyltransferase.

1 reference

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7 January 2021

Lack of galactose-alpha-1,3-galactose expression on porcine endothelial cells prevents complement-induced lysis but not direct xenogeneic NK cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Protective effects of recombinant human antithrombin III in pig-to-primate renal xenotransplantation

1 reference

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7 January 2021

Last chance to stop and think on risks of xenotransplants

1 reference

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7 January 2021

The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF-transgenic pig-to-primate life-supporting kidney xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903452-5

7 January 2021