(Q35723358)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Streffer JR

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

David D

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Schild A

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Hoerndli F

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Pennanen L

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Kurosinski P

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Chen F

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

0 references

publication date

1 July 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

664-683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.mp.4001508

26 December 2019

exact match

0 references

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An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde".

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7 January 2021

Alzheimer Disease in the US Population

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7 January 2021

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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7 January 2021

Amyloid plaque core protein in Alzheimer disease and Down syndrome

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7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

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7 January 2021

Reconstitution of gamma-secretase activity

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7 January 2021

Tau and transgenic animal models

1 reference

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7 January 2021

Neurodegenerative tauopathies

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7 January 2021

Subunit structure of paired helical filaments in Alzheimer's disease

1 reference

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7 January 2021

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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7 January 2021

Association of mitogen-activated protein kinase with the microtubule cytoskeleton

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7 January 2021

The pool of map kinase associated with microtubules is small but constitutively active

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7 January 2021

The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau

1 reference

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7 January 2021

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

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7 January 2021

Tau complexes with phospholipase C-gamma in situ

1 reference

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7 January 2021

Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies.

1 reference

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7 January 2021

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?

1 reference

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7 January 2021

Wnt signaling function in Alzheimer's disease

1 reference

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7 January 2021

Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments

1 reference

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7 January 2021

Somatodendritic localization of phosphorylated tau in neonatal and adult rat cerebral cortex.

1 reference

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7 January 2021

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

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7 January 2021

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

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7 January 2021

Structure and elasticity of microtubule-associated protein tau

1 reference

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7 January 2021

Heritability for Alzheimer's disease: the study of dementia in Swedish twins

1 reference

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7 January 2021

Causative and susceptibility genes for Alzheimer's disease: a review.

1 reference

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7 January 2021

The molecular and genetic basis of AD: the end of the beginning: the 2000 Wartenberg lecture.

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7 January 2021

Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease.

1 reference

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Sporadic and familial cerebral amyloid angiopathies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau gene mutation in familial progressive subcortical gliosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuropathological stageing of Alzheimer-related changes

1 reference

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7 January 2021

Staging of Alzheimer's disease-related neurofibrillary changes

1 reference

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7 January 2021

Phases of A beta-deposition in the human brain and its relevance for the development of AD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

1 reference

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7 January 2021

Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups

1 reference

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7 January 2021

Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria

1 reference

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7 January 2021

Familial presenile dementia with psychosis associated with cortical neurofibrillary tangles and degeneration of the amygdala

1 reference

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7 January 2021

Autosomal dominant dementia with widespread neurofibrillary tangles.

1 reference

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7 January 2021

A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)

1 reference

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7 January 2021

Tau pathology in a family with dementia and a P301L mutation in tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Phenotypic variation in hereditary frontotemporal dementia with tau mutations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Rapidly progressive autosomal dominant parkinsonism and dementia with pallido-ponto-nigral degeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Quantitative neuropathologic analysis of Pick's disease cases: cortical distribution of Pick bodies and coexistence with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Accuracy of clinical criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Corticodentatonigral Degeneration With Neuronal Achromasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Corticobasal degeneration. A clinical study of 36 cases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Glial inclusions in CNS degenerative diseases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau-positive glial inclusions in progressive supranuclear palsy, corticobasal degeneration and Pick's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alzheimer's disease is a synaptic failure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuron loss in APP transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Skeletal and CNS defects in Presenilin-1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Apolipoprotein E and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Role of apoE/Abeta interactions in Alzheimer's disease: insights from transgenic mouse models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Frontotemporal dementia: neuropil spheroids and presynaptic terminal degeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau filament formation in transgenic mice expressing P301L tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Oligodendroglial tau filament formation in transgenic mice expressing G272V tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Coexpression of human cdk5 and its activator p35 with human protein tau in neurons in brain of triple transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Transgenic and knockout models of PP2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Glial cells under physiologic and pathologic conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Proline-directed phosphorylation and isomerization in mitotic regulation and in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Emotion circuits in the brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Conditioned taste aversion as a learning and memory paradigm.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Impaired fear conditioning in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Gustatory and olfactory dysfunction in dementia: not specific to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Identification of 3'UTR region implicated in tau mRNA stabilization in neuronal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alzheimer's and Parkinson's disease--overlapping or synergistic pathologies?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Hyperphosphorylated tau and paired helical filament-like structures in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Stereologic analysis of neurofibrillary tangle formation in prefrontal cortex area 9 in aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Extensive dendritic sprouting induced by close axotomy of central neurons in the lamprey.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Analysis of Protein Domain Families inCaenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

The worm in us - Caenorhabditis elegans as a model of human disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Presenilin is required for proper morphology and function of neurons in C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alzheimer's disease: the cholesterol connection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Calpain inhibitors: a treatment for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Transgenic mouse models with tau pathology to test therapeutic agents for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Prevention and reduction of AD-type pathology in PDAPP mice immunized with A beta 1-42.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

The generation and characterization of potentially therapeutic Abeta antibodies in mice: differences according to strain and immunization protocol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Nerve inflammation halts trial for Alzheimer's drug.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Dosing in phase II trial of Alzheimer's vaccine suspended

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Cerebral hemorrhage after passive anti-Abeta immunotherapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001508

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001508

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15052274%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference