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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.
scientific article published in November 2001
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1 reference
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Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
title
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
author
Shermali Gunawardena
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
author name string
L S Goldstein
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2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
language of work or name
English
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publication date
1 November 2001
1 reference
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Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
published in
Neuron
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Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
volume
32
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
page(s)
389-401
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
cites work
Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis
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Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein
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GFP in Drosophila.
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Expression of APP in brains of transgenic mice containing the entire human APP gene.
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Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.
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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
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apl-1, a Caenorhabditis elegans gene encoding a protein related to the human beta-amyloid protein precursor
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Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the beta-amyloid precursor protein
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Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
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A Drosophila model of Parkinson's disease
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Identification of genes that modify ataxin-1-induced neurodegeneration.
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Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.
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7 January 2021
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Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype
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Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice
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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
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Kinesin light chains are essential for axonal transport in Drosophila
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Transduction. When worlds collide--trafficking in JNK.
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Microtubule-based transport systems in neurons: the roles of kinesins and dyneins
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Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction
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Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.
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Crossref
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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
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Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.
1 reference
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Crossref
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7 January 2021
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Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), and apolipoprotein E receptor, with late-onset Alzheimer's disease
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7 January 2021
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Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
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Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor
1 reference
stated in
Crossref
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Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene
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Crossref
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Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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inferred from DOI database lookup
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Alzheimer's disease: genetic studies and transgenic models
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Dynein, dynactin, and kinesin II's interaction with microtubules is regulated during bidirectional organelle transport
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
A Drosophila gene encoding a protein resembling the human beta-amyloid protein precursor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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inferred from DOI database lookup
The amyloid precursor protein of Alzheimer's disease and the Abeta peptide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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inferred from DOI database lookup
Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
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Search for the genes responsible for familial Alzheimer's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900496-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0896-6273(01)00496-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
PubMed publication ID
11709151
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11709151
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11709151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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