(Q48172460)

English

Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Moechars D

1

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

Lorent K

2

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

Van Leuven F

3

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

language of work or name

0 references

publication date

1 January 1999

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

91

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

3

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

819-830

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

Synaptic pathology in Alzheimer's disease: relation to severity of dementia, but not to senile plaques, neurofibrillary tangles, or the ApoE4 allele.

1 reference

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

1 reference

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7 January 2021

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The amyloid β protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reported

1 reference

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7 January 2021

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Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

1 reference

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7 January 2021

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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A heparin binding protein whose expression increases during differentiation of embryonal carcinoma cells to parietal endoderm cells: cDNA cloning and sequence analysis

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

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The mouse low density lipoprotein receptor gene: cDNA sequence and exon-intron structure

1 reference

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7 January 2021

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Structure and expression of mouse apolipoprotein E gene

1 reference

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7 January 2021

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inferred from DOI database lookup

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

1 reference

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein receptor-related protein gene.

1 reference

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Immunolocalization of cathepsin D in pneumocytes of normal human lung and in pulmonary fibrosis

1 reference

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The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

1 reference

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Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

1 reference

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Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues

1 reference

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7 January 2021

based on heuristic

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Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein li

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mouse heparin binding protein-44 (HBP-44) associates with brushin, a high-molecular-weight glycoprotein antigen common to the kidney and teratocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunocytochemical localization of amyloid precursor protein in rat brain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0306-4522%2898%2900599-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E and Alzheimer disease

1 reference

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based on heuristic

inferred from DOI database lookup

Synapsin I, synapsin II, and synaptophysin: marker proteins of synaptic vesicles

1 reference

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Immunohistochemical study of alpha 2 macroglobulin receptor in Alzheimer and control postmortem human brain.

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alpha 2-Macroglobulin expression in neuritic-type plaques in patients with Alzheimer's disease

1 reference

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Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA.

1 reference

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based on heuristic

inferred from DOI database lookup

A murine sequence-specific DNA binding protein shows extensive local similarities to the amyloid precursor protein

1 reference

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Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

1 reference

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Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles.

1 reference

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Evidence that A beta 42 is the real culprit in Alzheimer's disease.

1 reference

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Identifiers

10.1016/S0306-4522(98)00599-5

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10391465

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