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Insulin resistance and Alzheimer's disease
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Insulin resistance and Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
main subject
Alzheimer's disease
0 references
preproinsulin
1 reference
based on heuristic
inferred from title
insulin resistance
1 reference
based on heuristic
inferred from title
author name string
Suzanne M de la Monte
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
publication date
1 August 2009
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
published in
BMB Reports
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
volume
42
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
page(s)
475-481
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stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
cites work
Alzheimer's disease is type 3 diabetes-evidence reviewed
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PubMed Central
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2 October 2017
Epidemilogical trends strongly suggest exposures as etiologic agents in the pathogenesis of sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis.
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2 October 2017
Insulin resistance and steatosis in humans
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PubMed Central
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2 October 2017
Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism
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2 October 2017
Cognitive dysfunction in chronic hepatitis C: a review
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2 October 2017
Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells
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2 October 2017
Therapeutic use of agonists of the nuclear receptor PPARgamma in Alzheimer's disease
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2 October 2017
Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment
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PubMed Central
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2 October 2017
Diabetes mellitus and dementia.
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PubMed Central
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2 October 2017
Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease
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PubMed Central
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2 October 2017
Apolipoprotein E, cholesterol metabolism, diabetes, and the convergence of risk factors for Alzheimer's disease and cardiovascular disease.
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PubMed Central
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2 October 2017
Ceramides in insulin resistance and lipotoxicity
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2 October 2017
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine
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2 October 2017
The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease
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2 October 2017
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?
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2 October 2017
Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
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PubMed Central
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2 October 2017
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
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2 October 2017
GSK-3: tricks of the trade for a multi-tasking kinase
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
The aging brain. Changes in the neuronal insulin/insulin receptor signal transduction cascade trigger late-onset sporadic Alzheimer disease (SAD). A mini-review
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Does insulin dysfunction play a role in Alzheimer's disease?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19712582
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
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PubMed Central
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2 October 2017
Caspase cleavage enhances the apoptosis-inducing effects of BAD.
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2 October 2017
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway.
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PubMed Central
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2 October 2017
Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update
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PubMed Central
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2 October 2017
Structural and functional characterization of insulin receptor substrate proteins and the molecular mechanisms of their interaction with insulin superfamily tyrosine kinase receptors and effector proteins
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Mitochondria and cell death.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Regulation of neuronal survival by the serine-threonine protein kinase Akt
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
The role of the insulin-like growth factors in the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
The cellular and physiological actions of insulin in the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
retrieved
2 October 2017
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 October 2017
Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 July 2018
Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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2 July 2018
Intranasal insulin improves cognition and modulates beta-amyloid in early AD.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Depression, anxiety, and nonalcoholic steatohepatitis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection.
1 reference
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PubMed Central
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23 September 2018
Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Amyloid beta peptide processing, insulin degrading enzyme, and butyrylcholinesterase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
retrieved
23 September 2018
Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4600067
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23 September 2018
Wnt signaling function in Alzheimer's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19712582
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19712582
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19712582
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by Wortmannin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19712582
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
PMCID
4600067
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
PubMed ID
19712582
1 reference
stated in
Europe PubMed Central
PMCID
4600067
retrieved
12 August 2017
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