(Q36148378)

12 August 2017

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title

Miniaturization in functional genomics and proteomics (English)

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12 August 2017

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6

Hans Lehrach

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12 August 2017

Sascha Sauer

1

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12 August 2017

Bodo M H Lange

2

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12 August 2017

Johan Gobom

3

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12 August 2017

Lajos Nyarsik

4

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12 August 2017

Harald Seitz

5

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12 August 2017

1 June 2005

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12 August 2017

Nature Reviews Genetics

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12 August 2017

6

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12 August 2017

6

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12 August 2017

465-476

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https://scigraph.springernature.com/pub.10.1038/nrg1618

12 August 2017

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Global analysis of protein activities using proteome chips

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Laser-capture microdissection: opening the microscopic frontier to molecular analysis

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In situ localized amplification and contact replication of many individual DNA molecules

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A sequencing method based on real-time pyrophosphate

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Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase

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Chip-based genotyping by mass spectrometry

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Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry

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Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry

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Molecular haplotyping at high throughput.

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In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes

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Imprinting and disease

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DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project

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A modified and improved method for bisulphite based cytosine methylation analysis

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Tumour class prediction and discovery by microarray-based DNA methylation analysis

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A real-time PCR assay for DNA-methylation using methylation-specific blockers

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Delineation of prognostic biomarkers in prostate cancer

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Global identification of human transcribed sequences with genome tiling arrays

31 March 2020

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Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

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Mutation detection and single-molecule counting using isothermal rolling-circle amplification

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Post-analysis follow-up and validation of microarray experiments

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Microarrays of cells expressing defined cDNAs

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siRNAs: applications in functional genomics and potential as therapeutics

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Overview of structural genomics: from structure to function

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Protein expression systems for structural genomics and proteomics

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An overview of Ensembl

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Macromolecular electron microscopy in the era of structural genomics

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Single-particle imaging of macromolecules by cryo-electron microscopy

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Three-dimensional electron microscopy at molecular resolution

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The rapid identification of intact microorganisms using mass spectrometry

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Current developments in SELDI affinity technology

31 March 2020

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Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues

31 March 2020

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A Nonredundant Human Protein Chip for Antibody Screening and Serum Profiling

31 March 2020

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Current status of protein chip development in terms of fabrication and application

31 March 2020

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Analyzing antibody specificity with whole proteome microarrays

31 March 2020

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Microarrays to characterize protein interactions on a whole‐proteome scale

31 March 2020

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Toward optimized antibody microarrays: a comparison of current microarray support materials.

31 March 2020

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Protein microarray detection strategies: focus on direct detection technologies

31 March 2020

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A novel genetic system to detect protein-protein interactions

31 March 2020

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A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

31 March 2020

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A comprehensive two-hybrid analysis to explore the yeast protein interactome

31 March 2020

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Functional organization of the yeast proteome by systematic analysis of protein complexes

31 March 2020

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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

31 March 2020

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A generic protein purification method for protein complex characterization and proteome exploration

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A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

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Comparative assessment of large-scale data sets of protein-protein interactions

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High-throughput screening of surface displayed gene products

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Searching for DNA-protein interactions by lambda phage display.

31 March 2020

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Dissecting DNA-protein and protein-protein interactions involved in bacterial transcriptional regulation by a sensitive protein array method combining a near-infrared fluorescence detection

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Protein microarray technology and ultraviolet crosslinking combined with mass spectrometry for the analysis of protein-DNA interactions.

31 March 2020

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Regulation of gene expression by a metabolic enzyme

31 March 2020

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Quantifying DNA-protein interactions by double-stranded DNA arrays.

31 March 2020

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Exploring the DNA-binding specificities of zinc fingers with DNA microarrays

31 March 2020

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Quantitative high-throughput analysis of transcription factor binding specificities.

31 March 2020

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Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays.

31 March 2020

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

31 March 2020

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Recent advances in chemical genomics

31 March 2020

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Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays.

31 March 2020

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From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling

31 March 2020

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Profiling protein function with small molecule microarrays

31 March 2020

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SpeedScreen: label-free liquid chromatography-mass spectrometry-based high-throughput screening for the discovery of orphan protein ligands

31 March 2020

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Analysis of yeast protein kinases using protein chips.

31 March 2020

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Subnanoliter enzymatic assays on microarrays.

31 March 2020

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Microfabricated arrays of femtoliter chambers allow single molecule enzymology.

31 March 2020

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Technicolour transgenics: imaging tools for functional genomics in the mouse

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The molecular properties and applications of Anthozoa fluorescent proteins and chromoproteins.

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Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

31 March 2020

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Global analysis of protein localization in budding yeast

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Protein localization in proteomics

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31 March 2020

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Multiplexed protein profiling on microarrays by rolling-circle amplification

31 March 2020

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Protein detection using proximity-dependent DNA ligation assays.

31 March 2020

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Cytokine detection by antibody-based proximity ligation

31 March 2020

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Electrical biochip technology?a tool for microarrays and continuous monitoring

31 March 2020

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The impact of systems approaches on biological problems in drug discovery

31 March 2020

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Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine

31 March 2020

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Biochemical analysis with microfluidic systems

31 March 2020

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The 'right' size in nanobiotechnology

31 March 2020

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Integrated nanoliter systems

31 March 2020

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An integrated microfabricated cell sorter

31 March 2020

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Multichannel microchip electrospray mass spectrometry.

31 March 2020

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An integrated microfluidics-tandem mass spectrometry system for automated protein analysis

31 March 2020

1 reference

Integration of immobilized trypsin bead beds for protein digestion within a microfluidic chip incorporating capillary electrophoresis separations and an electrospray mass spectrometry interface.

31 March 2020

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A microchip-based proteolytic digestion system driven by electroosmotic pumping

31 March 2020

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Electrospray ion source. Another variation on the free-jet theme

31 March 2020

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Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

31 March 2020

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Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry

31 March 2020

1 reference

Translating biomolecular recognition into nanomechanics.

31 March 2020

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Nanowire nanosensors for highly sensitive and selective detection of biological and chemical species

31 March 2020

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Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors.

31 March 2020

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Optical imaging fiber-based single live cell arrays: a high-density cell assay platform

31 March 2020

1 reference

Cell-free protein expression and functional assay in nanowell chip format

31 March 2020

1 reference

Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules

31 March 2020

1 reference

Carbon nanotubes: from macromolecules to nanotechnology

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1618

1 reference

12 August 2017

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