(Q36149589)

12 August 2017

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title

Integrins as a distinct subtype of dependence receptors (English)

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12 August 2017

Stupack DG

1

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12 August 2017

1 August 2005

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Cell Death & Differentiation

12 August 2017

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12 August 2017

12

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12 August 2017

1021-1030

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12 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401658

12 August 2017

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cites work

Receptor protein tyrosine kinases and phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

The extracellular matrix as a cell survival factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

Control of motile and invasive cell phenotypes by focal adhesion kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

Increased apoptosis in metastatic human colonic adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

Evolution of protein kinase signaling from yeast to man

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Apoptosis and dependence receptors: a molecular basis for cellular addiction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Insulin-like growth factor receptor-1 as an anti-cancer target: blocking transformation and inducing apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Oncogenic derivatives of platelet-derived growth factor receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Neurotrophin dependence mediated by p75NTR: contrast between rescue by BDNF and NGF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The dependence receptors DCC and UNC5H as a link between neuronal guidance and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrins: bidirectional, allosteric signaling machines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrin signaling: specificity and control of cell survival and cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

1 reference

7 January 2021

Get a ligand, get a life: integrins, signaling and cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrins in vascular development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Perturbation of beta 1 integrin-mediated adhesions results in altered somite cell shape and behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The myofibroblast in wound healing and fibrocontractive diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Role of integrins in regulating epidermal adhesion, growth and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Latency and activation in the control of TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Correlation of overexpression of the low-affinity p75 neurotrophin receptor with augmented invasion and heparanase production in human malignant melanoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Comparative role of phosphotyrosine kinase domains of c-ros and c-ret protooncogenes in metanephric development with respect to growth factors and matrix morphogens.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Engineering cell shape and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrin signaling to the actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The tumor microenvironment as a determinant of drug response and resistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrin alpha2beta1 inhibits Fas-mediated apoptosis in T lymphocytes by protein phosphatase 2A-dependent activation of the MAPK/ERK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor-α-induced Apoptosis via the AKT/Survivin Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

1 reference

7 January 2021

Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Osteopontin deficiency in rat vascular smooth muscle cells is associated with an inability to adhere to collagen and increased apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Osteoprotegerin Is an αvβ3-induced, NF-κB-dependent Survival Factor for Endothelial Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Focal adhesion motility revealed in stationary fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires alphavbeta3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrin alpha(v)beta(3)-mediated activation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Inhibition of endothelial cell survival and angiogenesis by protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

FLICE/caspase-8 activation triggers anoikis induced by beta1-integrin blockade in human keratinocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Netrin-1 controls colorectal tumorigenesis by regulating apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Functional role of death-associated protein 3 (DAP3) in anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Extracellular matrix regulates glomerular epithelial cell survival and proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Caspase cleavage of members of the amyloid precursor family of proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Regulation of cell migration by the calcium-dependent protease calpain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Calpain cleavage of the cytoplasmic domain of the integrin beta 3 subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Cleavage of p130Cas in anoikis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Disruption of focal adhesions mediates detachment during neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Diverse roles of integrins in human T lymphocyte biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Structures of integrin domains and concerted conformational changes in the bidirectional signaling mechanism of alphaIIbbeta3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Mechanisms contributing to the activity of integrins on leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Periodic lamellipodial contractions correlate with rearward actin waves

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The relationship between force and focal complex development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

In vitro angiogenesis is modulated by the mechanical properties of fibrin gels and is related to alpha(v)beta3 integrin localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Dimensions and dynamics in integrin function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Anchorage-dependent ERK signaling--mechanisms and consequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Akt is an endogenous inhibitor toward tumor necrosis factor-related apoptosis inducing ligand-mediated apoptosis in rheumatoid synovial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Protein kinase B inhibits apoptosis induced by actinomycin D in ECV304 cells through phosphorylation of caspase 8.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Human cancer, PTEN and the PI-3 kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The integrin-linked kinase (ILK) suppresses anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Blockade of signaling via the very late antigen (VLA-4) and its counterligand vascular cell adhesion molecule-1 (VCAM-1) causes increased T cell apoptosis in experimental autoimmune neuritis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

The CD11/CD18 (beta2) integrins modulate neutrophil caspase activation and survival following TNF-alpha or endotoxin induced transendothelial migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Apoptotic cues from the extracellular matrix: regulators of angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Axis of evil: molecular mechanisms of cancer metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

New insights into the role of extracellular matrix during tumor onset and progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Differential inactivation of caspase-8 in lung cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401658

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401658

1 reference

PubMed ID

15933741

Dimensions Publication ID

12 August 2017

0 references

1 reference

PubMed ID

15933741