(Q36154958)

English

N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease (English)

1 reference

Europe PubMed Central

12 August 2017

molecular chaperones

0 references

Gaucher's disease

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

12 August 2017

Christopher P Austin

6

object named as

Christopher P Austin

1 reference

Europe PubMed Central

12 August 2017

Craig J. Thomas

7

object named as

Craig J Thomas

1 reference

Europe PubMed Central

12 August 2017

1

object named as

Wenwei Huang

1 reference

Europe PubMed Central

12 August 2017

author name string

Daniel J Urban

3

1 reference

Europe PubMed Central

12 August 2017

James Inglese

4

1 reference

Europe PubMed Central

12 August 2017

Ellen Sidransky

5

1 reference

Europe PubMed Central

12 August 2017

language of work or name

0 references

publication date

28 August 2007

1 reference

Europe PubMed Central

12 August 2017

Bioorganic & Medicinal Chemistry Letters

1 reference

Europe PubMed Central

12 August 2017

17

1 reference

Europe PubMed Central

12 August 2017

21

1 reference

Europe PubMed Central

12 August 2017

5783-5789

1 reference

Europe PubMed Central

12 August 2017

Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

Pharmacotherapeutic strategies using small molecules for the treatment of glycolipid lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

Therapeutic strategies to ameliorate lysosomal storage disorders--a focus on Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

The cell biology of lysosomal storage disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

A contradictory treatment for lysosomal storage disorders: inhibitors enhance mutant enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 October 2017

Novel inhibitors of Erm methyltransferases from NMR and parallel synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

2 July 2018

Chemical chaperones and permissive temperatures alter localization of Gaucher disease associated glucocerebrosidase variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

23 September 2018

Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

23 September 2018

The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2083578

23 September 2018

Replacement therapy for inherited enzyme deficiency--macrophage-targeted glucocerebrosidase for Gaucher's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17827006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of 2-[3,5-substituted pyrazol-1-yl]-4,6-trisubstituted triazine derivatives as antimalarial agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17827006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational design and synthesis of highly potent beta-glucocerebrosidase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17827006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of adamantan-1-yl-methoxy-functionalized 1-deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/17827006

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMCL.2007.08.050

1 reference

Europe PubMed Central

12 August 2017

release_n6voobgwdzf4rhquycw7h2p2im

1 reference

https://api.fatcat.wiki/v0/release/n6voobgwdzf4rhquycw7h2p2im

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

ResearchGate publication ID

0 references

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