(Q36158251)

English

Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Koji Shiraishi

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Mario Ascoli

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

5 April 2007

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

148

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

3214-3225

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation

1 reference

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2 October 2017

Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

A delayed gonadotropin-dependent and growth factor-mediated activation of the extracellular signal-regulated kinase 1/2 cascade negatively regulates aromatase expression in granulosa cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Activation of the lutropin/choriogonadotropin receptor in MA-10 cells stimulates tyrosine kinase cascades that activate ras and the extracellular signal regulated kinases (ERK1/2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Activation of the lutropin/choriogonadotropin receptor in MA-10 cells leads to the tyrosine phosphorylation of the focal adhesion kinase by a pathway that involves Src family kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Follicle-stimulating hormone-induced aromatase in immature rat Sertoli cells requires an active phosphatidylinositol 3-kinase pathway and is inhibited via the mitogen-activated protein kinase signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

What have we learned about gonadotropin function from gonadotropin subunit and receptor knockout mice?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

What have gonadotrophin overexpressing transgenic mice taught us about gonadal function?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

An update of the pathophysiology of human gonadotrophin subunit and receptor gene mutations and polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

The differential effects of the gonadotropin receptors on aromatase expression in primary cultures of immature rat granulosa cells are highly dependent on the density of receptors expressed and the activation of the inositol phosphate cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Multiple sites of tumorigenesis in transgenic mice overproducing hCG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Multiple signaling pathways regulating steroidogenesis and steroidogenic acute regulatory protein expression: more complicated than we thought

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Quest for selectivity in inhibition of matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

The Lutropin/Choriogonadotropin Receptor, A 2002 Perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

MA-10 cells transfected with the human lutropin/choriogonadotropin receptor (hLHR): a novel experimental paradigm to study the functional properties of the hLHR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Differentiation of the adult Leydig cell population in the postnatal testis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Mammalian MAP kinase signalling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Targeted disruption of luteinizing hormone/human chorionic gonadotropin receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Direct luteinizing hormone action triggers adrenocortical tumorigenesis in castrated mice transgenic for the murine inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Decreased cyclin A2 and increased cyclin G1 levels coincide with loss of proliferative capacity in rat Leydig cells during pubertal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Differentiation of adult Leydig cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Developmental changes in levels of luteinizing hormone receptor and androgen receptor in rat Leydig cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Epidermal Growth Factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 October 2017

Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 July 2018

Molecular mechanisms of reappearance of luteinizing hormone receptor expression and function in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 July 2018

Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 July 2018

Growth factor requirements for DNA synthesis by Leydig cells from the immature rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

2 July 2018

Extracellular signal-regulated kinases are involved in the acute activation of steroidogenesis in immature rat Leydig cells by human chorionic gonadotropin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

EGF-like growth factors as mediators of LH action in the ovulatory follicle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Development of leydig cells in the insulin-like growth factor-I (igf-I) knockout mouse: effects of igf-I replacement and gonadotropic stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Epac: a new cAMP target and new avenues in cAMP research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

The lutropin/choriogonadotropin receptor-induced phosphorylation of the extracellular signal-regulated kinases in leydig cells is mediated by a protein kinase a-dependent activation of ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Age-related decreases in Leydig cell testosterone production are not restored by exposure to LH in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Male LH-independent sexual precocity in a 3.5-year-old boy caused by a somatic activating mutation of the LH receptor in a Leydig cell tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Mutational analysis of the luteinizing hormone receptor gene in two individuals with Leydig cell tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Age-dependent stimulation of Leydig cell steroidogenesis by interleukin-1 isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

23 September 2018

Repopulation of Leydig Cells in Mature Rats after Selective Destruction of the Existent Leydig Cells with Ethylene Dimethane Sulfonate Is Dependent on Luteinizing Hormone and Not Follicle-Stimulating Hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2085235

5 December 2018

Variations in serum FSH, LH and testosterone levels in male rats from birth to sexual maturity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human epidermal growth factor and the proliferation of human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of the proliferation and differentiation of rat Leydig cell precursor cells after EDS administration or daily HCG treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the proliferation and differentiation of Leydig cell precursors after the destruction of existing Leydig cells with ethane dimethyl sulphonate (EDS) can take place in the absence of LH

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of Leydig cell precursors in vitro: a role for androgen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroidogenesis-inducing protein promotes deoxyribonucleic acid synthesis in Leydig cells from immature rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 stimulates deoxyribonucleic acid synthesis in immature rat Leydig cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leydig cell hyperplasia and adenomas in mice treated with finasteride, a 5 alpha-reductase inhibitor: a possible mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinases by gonadotropins and cyclic adenosine 5'-monophosphates in porcine granulosa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of gonadotrophins in regulating numbers of Leydig and Sertoli cells during fetal and postnatal development in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute signaling by the LH receptor is independent of protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lutropin/choriogonadotropin receptor, a 2002 perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/17412805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2007-0160

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

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